Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Michael J. Koukourakis"'
Autor:
John Kouvaris, Haralabos Zabatis, Georgios A. Zacharias, Michael J. Koukourakis, Vassilios Kouloulias, Georgios V. Koukourakis
Publikováno v:
Molecules, Vol 13, Iss 8, Pp 1897-1922 (2008)
Abstract: Capecitabine (Xeloda®) was developed as a pro-drug of fluorouracil (FU), with the aim of improving tolerability and intratumor drug concentrations through its tumorspecific conversion to the active drug. The purpose of this paper is
Externí odkaz:
https://doaj.org/article/619f08bf9850499c85baa31f7b0db518
Autor:
Stelios Kakolyris, Loukas Kaklamanis, Adrian L. Harris, Kevin C. Gatter, Helen Turley, Simon Biddolph, Michael J. Koukourakis
Publikováno v:
Angiogenesis. 2:49-55
Tumor angiogenesis, a crucial step in tumor growth and progression, is regulated by an increasing number of angiogenic factors. One of those is platelet-derived endothelial cell growth factor, recently shown to bethymidine phosphorylase (TP), which r
Autor:
Vassilis Georgoulias, Stylianos Kakolyris, Loukas Kaklamanis, Alexandra Giatromanolaki, Kevin C. Gatter, John Souglakos, Despina K. Reppa, Maria Rousomoustakaki, Michael J. Koukourakis, Adrian L. Harris
Publikováno v:
Oncology research. 12(4)
Angiogenesis, the formation of new vessels, is essential for tumor growth and metastasis. Mutations of p53 tumor suppressor gene are frequent and play an important role in colorectal oncogenesis. A role of p53 as an angiogenesis inhibitor has also be