Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Michael J. Kimber"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Brugia malayi are thread-like parasitic worms and one of the etiological agents of Lymphatic filariasis (LF). Existing anthelmintic drugs to treat LF are effective in reducing the larval microfilaria (mf) counts in human bloodstream but are
Externí odkaz:
https://doaj.org/article/81dd60d6a3df4058a2811bedc1c87a84
Autor:
Hannah J. Loghry, Hyeogsun Kwon, Ryan C. Smith, Noelle A. Sondjaja, Sarah J. Minkler, Sophie Young, Nicolas J. Wheeler, Mostafa Zamanian, Lyric C. Bartholomay, Michael J. Kimber
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Vector-borne, filarial nematode diseases cause significant disease burdens in humans and domestic animals worldwide. Although there is strong direct evidence of parasite-driven immunomodulation of mammalian host responses, there is less evid
Externí odkaz:
https://doaj.org/article/9904ca224c1d4f2093009ccf32b912f5
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Lymphatic filariasis (LF) is a mosquito-borne disease caused by filarial nematodes including Brugia malayi. Over 860 million people worldwide are infected or at risk of infection in 72 endemic countries. The absence of a protective vaccine means that
Externí odkaz:
https://doaj.org/article/e506f7038f48450d8211849a3214cf47
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Circular RNAs (circRNAs) are a recently identified RNA species with emerging functional roles as microRNA (miRNA) and protein sponges, regulators of gene transcription and translation, and modulators of fundamental biological processes including immu
Externí odkaz:
https://doaj.org/article/35fd1b82af3248e983bbddd3f5884a59
Autor:
Amanda E. Bries, Joe L. Webb, Brooke Vogel, Claudia Carrillo, Timothy A. Day, Michael J. Kimber, Rudy J. Valentine, Matthew J. Rowling, Stephanie Clark, Kevin L. Schalinske, Elizabeth M. McNeill
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
Eggs are protein-rich, nutrient-dense, and contain bioactive ingredients that have been shown to modify gene expression and impact health. To understand the effects of egg consumption on tissue-specific mRNA and microRNA expression, we examined the r
Externí odkaz:
https://doaj.org/article/59446391f23848fcb0ae79b410464e2e
Autor:
Ciaran J. McCoy, Louise E. Atkinson, Mostafa Zamanian, Paul McVeigh, Tim A. Day, Michael J. Kimber, Nikki J. Marks, Aaron G. Maule, Angela Mousley
Publikováno v:
EuPA Open Proteomics, Vol 3, Iss C, Pp 262-272 (2014)
FMRFamide-like peptide (FLP) receptors are appealing as putative anthelmintic targets. To date, 31 flp-encoding genes have been identified in Caenorhabditis elegans and thirteen FLP-activated G-protein coupled receptors (FLP-GPCRs) have been reported
Externí odkaz:
https://doaj.org/article/f284ff25b85a470d9d14b0a507f06864
Publikováno v:
Lab on a Chip. 21:3541-3549
Exosomes have been considered as high-quality biomarkers for disease diagnosis, as they are secreted by cells into extracellular environments as nanovesicles with rich and unique molecular information, and can be isolated and enriched from clinical s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d561194bcec6ee10697776ceb18d5be
https://doi.org/10.1039/d1lc00446h
https://doi.org/10.1039/d1lc00446h
Autor:
Hannah J. Loghry, Hyeogsun Kwon, Ryan C Smith, Noelle A Sondjaja, Sarah J Minkler, Sophie Young, Nicolas J Wheeler, Mostafa Zamanian, Lyric C Bartholomay, Michael J Kimber
Vector-borne, filarial nematode diseases represent a significant and affecting disease burden in humans, domestic animals, and livestock worldwide. Parasitic filarial nematodes require both an intermediate (vector) host and a definitive (mammalian) h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eaebc474c3733d2cbfdc73adaccb7c0
https://doi.org/10.1101/2022.04.11.487926
https://doi.org/10.1101/2022.04.11.487926
Autor:
Lawrance Chandra, Wang Yuan, Martin G. Martin, Martin E. Fernandez-Zapico, Karin Allenspach, Dawn Kingsbury, Elizabeth M. Snella, Michael J. Wannemuehler, Todd Atherly, Qun Wang, Dana C. Borcherding, Yoko M. Ambrosini, Albert E. Jergens, Melissa C. Skala, Mary K. Estes, Yijun Qi, Michael J. Kimber, Jonathan P. Mochel, Agnes Bourgois-Mochel, N. Matthew Ellinwood, David K. Meyerholz
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-21 (2019)
BMC Biology
BMC Biology
Background Large animal models, such as the dog, are increasingly being used for studying diseases including gastrointestinal (GI) disorders. Dogs share similar environmental, genomic, anatomical, and intestinal physiologic features with humans. To b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b232835f770f5ec5d8d56a1f663be2
http://link.springer.com/article/10.1186/s12915-019-0652-6
http://link.springer.com/article/10.1186/s12915-019-0652-6
Autor:
Sarah Minkler, Fabrice Lucien, Chad M Johannes, Igor Frank, Agnes Bourgois-Mochel, Michael J. Kimber, Margaret L. Musser, Dipak Kumar Sahoo, Jonathan P. Mochel, Karin Allenspach, John C. Cheville
Publikováno v:
Cancers
Cancers, Vol 13, Iss 422, p 422 (2021)
Cancers, Vol 13, Iss 422, p 422 (2021)
Simple Summary Urinary bladder cancer (UBC) is one of the most common and deadly cancers worldwide, with many patients not responding to chemotherapy, or presenting with serious adverse effects after chemotherapy. Yet, current bench side assays provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be9fb48c5f52da5c5c3f4062f70b776
https://pubmed.ncbi.nlm.nih.gov/33498666
https://pubmed.ncbi.nlm.nih.gov/33498666