Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael J. Keherly"'
Autor:
Michael J. Keherly, Roderic H. Fabian, Vicki M. Soukup, Kimberly W. Schuenke, Christopher J. Lahart, Benjamin B. Gelman, Frances J. Richey, Charles E. Holzer
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 39:422-425
Expansion of the lysosomal apparatus occurs in subcortical white matter in brains from persons with AIDS. This study examined whether HIV-associated subcortical dementia (HAD) is significantly related to this lysosomal anomaly. Brain cortex and adjac
Autor:
Charles E. Holzer, Michael J. Keherly, Kimberly W. Schuenke, Benjamin B. Gelman, Christopher J. Lahart, Frances J. Richey, Vicki M. Soukup
Publikováno v:
Journal of Neuroimmunology. 157:111-119
A gene expression profile of the human brain cortex was performed in people with HIV-1-associated dementia (HAD) using Affymetrix HG-U133 chips. Messenger RNA transcripts in middle frontal gyrus from subjects with HAD or milder neurocognitive dysfunc
Autor:
Antonella Naldini, Fabio Carraro, C. Bernini, Cosima T. Baldari, Silvia Rossi Paccani, Darrell H. Carney, Michael J. Keherly
Publikováno v:
Peptides. 25:1917-1926
The thrombin peptide, TP508, accelerates tissue repair and initiates a cascade of cellular events. We have previously shown that α-thrombin induces cytokine expression in human mononuclear cells. We, therefore, investigated the possibility that TP50
Autor:
Daryl E. Warder, Michael J. Keherly
Publikováno v:
Journal of Biomedical Science. 10:406-417
Autor:
Ching Chyuan Hsieh, John Papaconstantinou, Jerome L. McCombs, Michael J. Keherly, Linda S. Merryman
Publikováno v:
Somatic Cell and Molecular Genetics. 22:119-134
We utilized an AFP-HPRT transgene, i.e. the HPRT coding sequences under the regulation of AFP enhancer and promoter sequences, to localize the AFP extinguisher locus in intertypic somatic cell hybrids (hepatoma X fibroblast). This hybrid gene constru
Autor:
Chuan Ye Tang, Corazon A. Menguito, Paul H. Weigel, John Papaconstantinou, Michael J. Keherly
Publikováno v:
Nucleic Acids Research. 21:615-620
The histidyl-tRNA synthetase gene (hisS) from Streptococcus equisimilis was cloned and sequenced. The gene for this aminoacyl-tRNA synthetase has an open reading frame of 1278 nucleotides. The deduced amino acid sequence encodes a protein of 426 amin
Autor:
Daryl E. Warder, Michael J. Keherly
Publikováno v:
Journal of biomedical science. 10(4)
The matrin 3 family of nuclear proteins consists of members with potentially diverse activities. Matrin 3 and NP220 share RNA-binding domains, and NP220 has been shown to recognize and bind to the DNA sequence, CCCCC (G/C). We have isolated and chara
Autor:
Narayanamma Madamanchi, Todd T. Trier, Michael J. Keherly, Jeff W. Chen, Nageswara R. Madamanchi
Publikováno v:
Journal of biomedical science. 8(4)
Lysosome-associated membrane protein (LAMP)-1, one of the major protein components of the lysosomal membrane, is upregulated in the human glioblastoma cell lines, U-373 MG and LN-Z308, which undergo cisplatin-induced apoptosis. These human brain tumo
Publikováno v:
Journal of neuropathology and experimental neurology. 55(11)
Fragmentation of genomic DNA, a major biochemical feature of programmed cell death (apoptosis), is easily detected when apoptosis is prevalent. In brain tissue apoptotic cells are usually scarce and detection requires more sensitive techniques. We de
Publikováno v:
Experimental cell research. 205(2)
We describe a sequential staining technique for the karyotypic analysis of interspecific mouse × human somatic cell hybrids. Fluorescence in situ hybridization of samples, previously stained using standard trypsin/Giemsa protocols, was instrumental