Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Michael J. Ingeno"'
Publikováno v:
Biochemical and Biophysical Research Communications. 136:273-280
The microbial iron chelator vibriobactin, N-[3-(2,3-dihydroxybenzamido)propyl]-1,3-bis[2-(2, 3-dihydroxyphenyl)-trans-5-methyl-2-oxazoline-4-carboxamido]-propane, is shown to inhibit the growth of L1210 cells in culture, with an IC50 value of 2 micro
Autor:
Allen H. Neims, Michael J. Ingeno, Thomas R. Hawthorne, John R. T. Vinson, Raymond J. Bergeron, James S. McManis, Rita Bortell
Publikováno v:
Journal of medicinal chemistry. 31(6)
In this paper, we report on the synthesis and biological activity of a number of N-alkylated spermine compounds. The dialkylspermines N1,N12-dimethylspermine (DMSPM-2), N1,N12-diethylspermine (DESPM-3), and N1,N12-dipropylspermine (DPSPM-4) are all s