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pro vyhledávání: '"Michael J. Iammarino"'
Autor:
Dmitri A. Pissarnitski, Ahmet Kekec, Lin Yan, Yuping Zhu, Danqing D. Feng, Pei Huo, Christina Madsen-Duggan, Christopher R. Moyes, Ravi P. Nargund, Terri Kelly, Xiaoping Zhang, Ester Carballo-Jane, Judith Gorski, Peter Zafian, Mo Qatanani, Niels Kaarsholm, Fanyu Meng, Xiujuan Jia, Keun-Joong Lee, Weixun Wang, Sherrie Xu, Michael J. Hohn, Michael J. Iammarino, Mark A. McCoy, Grace A. Okoh, Yingkai Liang, Scott A. Hollingsworth, Mark D. Erion, David E. Kelley, Robert M. Garbaccio, Amy Zhang, James Mu, Songnian Lin
Publikováno v:
Journal of Medicinal Chemistry. 65:5593-5605
We have identified a series of novel insulin receptor partial agonists (IRPAs) with a potential to mitigate the risk of hypoglycemia associated with the use of insulin as an antidiabetic treatment. These molecules were designed as dimers of native in