Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Michael J. Galko"'
Publikováno v:
Biology Open, Vol 12, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/2d750cc0bd3e466384866b2d925be77f
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 5 (2018)
Diabetes-associated nociceptive hypersensitivity affects diabetic patients with hard-to-treat chronic pain. Because multiple tissues are affected by systemic alterations in insulin signaling, the functional locus of insulin signaling in diabetes-asso
Externí odkaz:
https://doaj.org/article/128882a28bf643f3a28c07bab27bd66e
Autor:
Chang-Ru Tsai, Yan Wang, Alec Jacobson, Niki Sankoorikkal, Josue D Chirinos, Sirisha Burra, Nishanth Makthal, Muthiah Kumaraswami, Michael J Galko
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 12, Iss 1 (2021)
AbstractTissue injury is typically accompanied by inflammation. In Drosophila melanogasterspreading in vivoin vitroin vitroin vivo
Externí odkaz:
https://doaj.org/article/7f72aab938a64a36a1d65c116f99169d
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209577 (2018)
Nociceptive sensitization involves an increase in responsiveness of pain sensing neurons to sensory stimuli, typically through the lowering of their nociceptive threshold. Nociceptive sensitization is common following tissue damage, inflammation, and
Externí odkaz:
https://doaj.org/article/22d562d1e0044d61a0051ed8ea26f0d8
Early phase diabetes is often accompanied by pain sensitization. In the fruit fly Drosophila, the insulin receptor (InR) regulates the persistence of injury-induced thermal nociceptive sensitization. Whether Drosophila InR also regulates the persiste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a86bc7337fb3beb3ab2a8097935bb86
https://doi.org/10.1101/2022.04.02.486841
https://doi.org/10.1101/2022.04.02.486841
Autor:
Alec Jacobson, Yan Wang, Sirisha Burra, Chang-Ru Tsai, Muthiah Kumaraswami, Josue D Chirinos, Michael J. Galko, Nishanth Makthal, Niki Sankoorikkal
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 12, Iss 1 (2021)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Tissue injury is typically accompanied by inflammation. In Drosophila melanogaster larvae, wound-induced inflammation involves adhesive capture of hemocytes at the wound surface followed by hemocyte spreading to assume a flat, lamellar morphology. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c22a0f557c9d0f21d3db4b61753c36a
https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkab388
https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkab388
Autor:
Seol Hee Im, Kendra Takle, Juyeon Jo, Daniel T Babcock, Zhiguo Ma, Yang Xiang, Michael J Galko
Publikováno v:
eLife, Vol 4 (2015)
Pain signaling in vertebrates is modulated by neuropeptides like Substance P (SP). To determine whether such modulation is conserved and potentially uncover novel interactions between nociceptive signaling pathways we examined SP/Tachykinin signaling
Externí odkaz:
https://doaj.org/article/522f8d3c8ef9484ba0c3cc37a756b006
Autor:
Yuanxin Wang, Maktal N, Sirisha Burra, Jacobson A, Muthiah Kumaraswami, Michael J. Galko, Chirinos Jd, Sankoorikal N, Chi-Lin Tsai
Tissue injury is typically accompanied by inflammation. In Drosophila melanogaster, wound-induced inflammation involves adhesive capture of hemocytes at the wound surface followed by hemocyte spreading to assume a flat, lamellar morphology. The facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d58f11c0f5f11ad824459e95b6825cd
https://doi.org/10.1101/2021.06.10.447972
https://doi.org/10.1101/2021.06.10.447972
Autor:
Howard B. Gutstein, Heather N. Turner, Michael J. Galko, Chang Ru Tsai, Patrick J. Huang, Roger López-Bellido, Stephanie Puig
Publikováno v:
The Journal of Neuroscience. 39:6012-6030
Mechanical sensitization is one of the most difficult clinical pain problems to treat. However, the molecular and genetic bases of mechanical nociception are unclear. Here we develop a Drosophila model of mechanical nociception to investigate the ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c1610337ef538451393fa600282eb0c
https://doi.org/10.1523/jneurosci.2950-18.2019
https://doi.org/10.1523/jneurosci.2950-18.2019
Autor:
Roger, Lopez-Bellido, Michael J, Galko
Publikováno v:
J Vis Exp
Published assays for mechanical nociception in Drosophila have led to variable assessments of behavior. Here, we fabricated, for use with Drosophila larvae, customized metal nickel-titanium alloy (nitinol) filaments. These mechanical probes are simil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c157acf8c07be88b0d013152b0564b1b
https://pubmed.ncbi.nlm.nih.gov/33191934
https://pubmed.ncbi.nlm.nih.gov/33191934