Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Michael J. Fairchild"'
Autor:
Wenjun Zhu, Guodong Liu, Wenguang Cao, Shihua He, Anders Leung, Ute Ströher, Michael J. Fairchild, Rick Nichols, Joseph Crowell, Joan Fusco, Logan Banadyga
Publikováno v:
Vaccines, Vol 10, Iss 7, p 1004 (2022)
Marburg virus (MARV) is a negative-sense, single-stranded RNA virus that belongs to the Filoviridae family. Despite having caused numerous outbreaks of severe hemorrhagic fever with high case fatality rates, there are still no clinically approved the
Externí odkaz:
https://doaj.org/article/754c6112c51146dcbd11087858918e5e
Autor:
Elliott J. Hagedorn, Julie R. Perlin, Rebecca J. Freeman, Samuel J. Wattrus, Tianxiao Han, Clara Mao, Ji Wook Kim, Inés Fernández-Maestre, Madeleine L. Daily, Christopher D’Amato, Michael J. Fairchild, Raquel Riquelme, Brian Li, Dana A.V.E. Ragoonanan, Khaliun Enkhbayar, Emily L. Henault, Helen G. Wang, Shelby E. Redfield, Samantha H. Collins, Asher Lichtig, Song Yang, Yi Zhou, Balvir Kunar, Jesus Maria Gomez-Salinero, Thanh T. Dinh, Junliang Pan, Karoline Holler, Henry A. Feldman, Eugene C. Butcher, Alexander van Oudenaarden, Shahin Rafii, J. Philipp Junker, Leonard I. Zon
The hematopoietic niche is a supportive microenvironment composed of distinct cell types, including specialized vascular endothelial cells that directly interact with hematopoietic stem and progenitor cells (HSPCs). The molecular factors that specify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b90a91fb7a197e73cc3374b0f18cdb
http://edoc.mdc-berlin.de/23329/7/23329suppl.zip
http://edoc.mdc-berlin.de/23329/7/23329suppl.zip
Autor:
Michael J. Fairchild, Rebecca J. Freeman, Khaliun Enkhbayar, Samantha H. Collins, Samuel J. Wattrus, Eugene C. Butcher, Helen G. Wang, Jesus M. Gomez-Salinero, Elliott J. Hagedorn, Julie R. Perlin, Yi Zhou, Inés Fernández-Maestre, Brian Li, Christopher D’Amato, Emily L. Henault, Henry A. Feldman, Thanh Theresa Dinh, Alexander van Oudenaarden, Leonard I. Zon, Shelby E. Redfield, Raquel Riquelme, Shahin Rafii, Asher Lichtig, Song Yang, Karoline Holler, Junliang Pan, Clara Mao, Balvir Kunar, Tianxiao Han, Dana A.V.E. Ragoonanan, Ji Wook Kim, J. Philipp Junker, Madeleine L. Daily
The hematopoietic niche is a supportive microenvironment comprised of distinct cell types, including specialized vascular endothelial cells that directly interact with hematopoietic stem and progenitor cells (HSPCs). The molecular factors that specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b26e49458391b494ac77ae49a8e22607
https://doi.org/10.1101/2021.11.03.467105
https://doi.org/10.1101/2021.11.03.467105
Autor:
Stephanie J Ellis, Emily Lostchuck, Benjamin T Goult, Mohamed Bouaouina, Michael J Fairchild, Pablo López-Ceballos, David A Calderwood, Guy Tanentzapf
Publikováno v:
PLoS Genetics, Vol 10, Iss 11, p e1004756 (2014)
Talin serves an essential function during integrin-mediated adhesion in linking integrins to actin via the intracellular adhesion complex. In addition, the N-terminal head domain of talin regulates the affinity of integrins for their ECM-ligands, a p
Externí odkaz:
https://doaj.org/article/1b818ca43afb49acb52ce35d0b768eac
Autor:
Karoline Holler, Junliang Pan, Michael J. Fairchild, Julie R. Perlin, Shahin Rafii, Samuel J. Wattrus, Jesus M. Gomez-Salinero, Song Yang, Raquel Riquelme, Elliott J. Hagedorn, Inés Fernández-Maestre, Jan Philipp Junker, Samantha H. Collins, Madeleine L. Daily, Alexander van Oudenaarden, Theresa T. Dinh, Shelby E. Redfield, Tianxiao Han, Rebecca J. Freeman, Clara Mao, Leonard I. Zon, Eugene C. Butcher, Brian Li, Asher Lichtig, Christopher R. D'Amato, Balvir Kunar, Yi Zhou
Publikováno v:
Blood. 134:525-525
The hematopoietic stem and progenitor cell (HSPC) niche is a supportive microenvironment comprised of distinct cell types, including specialized vascular endothelial cells (ECs) that directly interact with HSPCs and promote stem cell function. Utiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aacb34c00c72daac08de1cbab903d08
https://doi.org/10.1182/blood-2019-127219
https://doi.org/10.1182/blood-2019-127219
Autor:
Mark Peifer, Guy Tanentzapf, Benjamin T. Goult, Nathan J. Harris, Paolo A. Lobo, Michael J. Fairchild, Jenny Yanyan Long, Frieder Schöck, Stephanie J. Ellis, Stefan Czerniecki, Filip Van Petegem
Publikováno v:
Current Biology. 23:1825-1833
SummaryThe establishment of a multicellular body plan requires coordinating changes in cell adhesion and the cytoskeleton to ensure proper cell shape and position within a tissue. Cell adhesion to the extracellular matrix (ECM) via integrins plays di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5711feb3b84e1fc8729672a383a467
https://doi.org/10.1016/j.cub.2013.07.054
https://doi.org/10.1016/j.cub.2013.07.054
Publikováno v:
Current biology : CB. 26(18)
Summary Stem cells can be controlled by their local microenvironment, known as the stem cell niche. The Drosophila testes contain a morphologically distinct niche called the hub, composed of a cluster of between 8 and 20 cells known as hub cells, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbebc4c72032ec9535de559f4726a88
https://pubmed.ncbi.nlm.nih.gov/27546574
https://pubmed.ncbi.nlm.nih.gov/27546574
Publikováno v:
Developmental Dynamics. 240:36-51
Cell adhesion must be precisely regulated to enable both dynamic morphogenetic processes and the subsequent transition to stable tissue maintenance. Integrins link the intracellular cytoskeleton and extracellular matrix, relaying bidirectional signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f76eb0435100ca18c0355c4eda9df68
https://doi.org/10.1002/dvdy.22488
https://doi.org/10.1002/dvdy.22488
Autor:
Filip Van Petegem, Tsz Ying Sylvia Cheung, Michael J. Fairchild, Guy Tanentzapf, Raz Zarivach
Publikováno v:
Journal of Molecular Biology. 387:787-793
Integrins are transmembrane receptors that mediate cell adhesion to the extracellular matrix and play essential roles in tissue development and maintenance. The cytoplasmic segment of integrin associates with talin, a large intracellular protein that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8271221b7100e8339539b2ae2cd674a
https://doi.org/10.1016/j.jmb.2009.01.053
https://doi.org/10.1016/j.jmb.2009.01.053
Publikováno v:
Development (Cambridge, England). 142(2)
Interactions between the soma and germline are essential for gametogenesis. In the Drosophila testis, differentiating germ cells are encapsulated by two somatic cells that surround the germline throughout spermatogenesis. chickadee (chic), the fly or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132c07e4ba852d41e212e9b8de2edd87
https://pubmed.ncbi.nlm.nih.gov/25503408
https://pubmed.ncbi.nlm.nih.gov/25503408