Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Michael J. Eppihimer"'
Autor:
Kimberly A. Robertson, Angela Marks, Kimberly J. Berg, Douglas E. Pennington, Natalia Sushkova, Gregory J. Wilson, Yen-Lane Chen, David Knapp, Aaron Foss, Keith D. Dawkins, Barbara Huibregtse, Steve P Hawley, Michael J. Eppihimer
Publikováno v:
Catheterization and Cardiovascular Interventions. 86:E247-E257
Aims SYNERGY is a novel platinum chromium alloy stent that delivers abluminal everolimus from an ultrathin poly-lactide-co-glycide (PLGA) biodegradable polymer. This study evaluated the in vivo degradation of the polymer coating, everolimus release t
Autor:
Jennifer McGregor, Steven P Hawley, Gregory J. Wilson, Masahiko Shibuya, Gerard Conditt, Keith D. Dawkins, Serge D Rouselle, Michael J. Eppihimer, Juan F. Granada, Barbara Huibregtse, Natalia Sushkova
Publikováno v:
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. 13(14)
AIMS Drug-eluting stents (DES) have evolved to using bioresorbable polymers as a method of drug delivery. The impact of bioresorbable polymer on long-term neointimal formation, inflammation, and healing has not been fully characterised. This study ai
Autor:
Cory Hitzman, Gordon Kocur, Dongming Hou, Michael J. Eppihimer, John Heil, William Conrad Stoffregen, Barbara Huibregtse, Elizabeth Stejskal, Keith D. Dawkins
Publikováno v:
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. 12(6)
Aims Our aim was to evaluate arterial responses to paclitaxel and a novel fluorocopolymer-coated nitinol low-dose paclitaxel-eluting stent (FP-PES). Methods and results Human smooth muscle cell (SMC) migration was assessed after exposure to paclitaxe
Autor:
Dawn Winsor-Hines, Dongming Hou, Nicolas Chronos, Michael J. Eppihimer, Spencer B. King, Natalia Sushkova, Keith D. Dawkins, Xinhua Yin, Jack P. Chen, Takamitsu Nakamura, Barbara Huibregtse
Publikováno v:
EuroIntervention. 8:493-500
AIMS To evaluate the time-course of vasomotor function and re-endothelialisation after implantation of a novel platinum-chromium (PtCr) abluminal biodegradable polymer-coated paclitaxel-eluting stent (PES, Labcoat Element) in rabbit iliac arteries. M
Autor:
Aloke V. Finn, Tucker Ezell, Chitra Raghunathan, Talina Davis, Frank D. Kolodgie, Michael J. Eppihimer, Xin Xu, Scott Lajoie, Gaku Nakazawa, Herman K. Gold, Michael C. John, Renu Virmani, Vinit Karmali, Rohini Polavarapu, Eduardo Acampado, Qi Cheng
Publikováno v:
Circulation Research. 105:1003-1012
Rationale: Sirolimus-eluting coronary stents (SESs) and paclitaxel-eluting coronary stents (PESs) are used to reduce restenosis but have different sites of action. The molecular targets of sirolimus overlap with those of the peroxisome proliferator-a
Publikováno v:
Microcirculation. 11:655-668
To delineate the relative contributions of alpha4 and alphaL to mediate interleukin-4 (IL-4) induced leukocyte rolling, and the subsets of leukocytes that use these pathways to adhere.Intravital microscopy was used to examine leukocytes in venules of
Autor:
Michael J. Grusby, Wood Nancy L, Samuel J. Goldman, Joann S. Witek, Unger Michelle J, Takashi Tanaka, Marion T. Kasaian, Michael J. Eppihimer, Bruce A. Jacobson, Debra D. Donaldson, Joseph P. Sypek, Matthew J. Whitters, Mary Collins
Publikováno v:
The Journal of Experimental Medicine
Interleukin (IL)-13 has recently been shown to play important and unique roles in asthma, parasite immunity, and tumor recurrence. At least two distinct receptor components, IL-4 receptor (R)α and IL-13Rα1, mediate the diverse actions of IL-13. We
Autor:
Robert G. Schaub, Michael J. Eppihimer
Publikováno v:
Microcirculation. 8:15-24
Objective:Leukocyte rolling is recognized as an important event in facilitating the extravasation of leukocytes from the vascular to the interstitial compartment, and is mediated by the selectin family of cell adhesion molecules. The aim of this stud
Autor:
Robert G. Schaub, Michael J. Eppihimer
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 20:2483-2488
Abstract —Leukocyte adhesion, transendothelial migration, and stasis are important components in the pathogenesis of deep vein thrombosis. Anesthetized cats were treated with saline, a recombinant soluble form of P-selectin glycoprotein ligand-1 (r
Publikováno v:
Shock. 11:93-97
Tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma), potent inflammatory cytokines, are released by macrophages during endotoxin shock. However, the contribution of these cytokines to endotoxin-induced inflammation has not been d