Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Michael J. E. Sternberg"'
Autor:
Luis G. Leal, Clive Hoggart, Marjo‐Riitta Jarvelin, Karl‐Heinz Herzig, Michael J. E. Sternberg, Alessia David
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 6, Pp n/a-n/a (2020)
Abstract Background Severe hypercholesterolemia (HC, LDL‐C > 4.9 mmol/L) affects over 30 million people worldwide. In this study, we validated a new polygenic risk score (PRS) for LDL‐C. Methods Summary statistics from the Global Lipid Genome Con
Externí odkaz:
https://doaj.org/article/c1899659dec54d3393d256b9caa83a51
Autor:
William A. Bryant, Régis Stentz, Gwenaelle Le Gall, Michael J. E. Sternberg, Simon R. Carding, Thomas Wilhelm
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
The interactions between the gut microbiota and its host are of central importance to the health of the host. Outer membrane vesicles (OMVs) are produced ubiquitously by Gram-negative bacteria including the gut commensal Bacteroides thetaiotaomicron.
Externí odkaz:
https://doaj.org/article/9d4359788872456090e0abdf50873756
Autor:
Jake E McGreig, Hannah Uri, Magdalena Antczak, Michael J E Sternberg, Martin Michaelis, Mark N Wass
Publikováno v:
W1=20
W13
W13
3DLigandSite is a web tool for the prediction of ligand-binding sites in proteins. Here, we report a significant update since the first release of 3DLigandSite in 2010. The overall methodology remains the same, with candidate binding sites in protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b018cc9e3240a58405756f11d00321c
https://pubmed.ncbi.nlm.nih.gov/35412635
https://pubmed.ncbi.nlm.nih.gov/35412635
Thailand was the first country outside China to officially report COVID-19 cases. Despite the strict regulations for international arrivals, up until February 2021, Thailand had been hit by two major outbreaks. With a large number of SARS-CoV-2 seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cac5f33f62a470df869823f20b5af799
https://doi.org/10.1101/2022.01.01.474713
https://doi.org/10.1101/2022.01.01.474713
Autor:
Boris, Lenhard, Michael J E, Sternberg
Publikováno v:
Journal of Molecular Biology. 432:3361-3363
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc9fe7f91a2e7139cab97cdc34d9b72
https://doi.org/10.1016/j.jmb.2020.04.010
https://doi.org/10.1016/j.jmb.2020.04.010
Autor:
Boris, Lenhard, Michael J E, Sternberg
Publikováno v:
Journal of Molecular Biology. 431:2395-2397
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d954cbc96435146e087071cda2ad55
https://doi.org/10.1016/j.jmb.2019.05.034
https://doi.org/10.1016/j.jmb.2019.05.034
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 77:C95-C95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a4f67f670f54eb3e7d2136fb0e076f2
https://doi.org/10.1107/s0108767321095842
https://doi.org/10.1107/s0108767321095842
Publikováno v:
Machine Intelligence 15: Intelligent Agents.
Externí odkaz:
https://doi.org/10.1093/oso/9780198538677.003.0018
Publikováno v:
Bioinformatics (Oxford, England). 34(12)
Genome-wide association studies have identified thousands of loci associated with human disease, but identifying the causal genes at these loci is often difficult. Several methods prioritize genes most likely to be disease causing through the integra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7bf87fbbaa81d53a03213845eb15f49
https://pubmed.ncbi.nlm.nih.gov/29360927
https://pubmed.ncbi.nlm.nih.gov/29360927
Autor:
Sandeep, Sundriyal, Sébastien, Moniot, Zimam, Mahmud, Shang, Yao, Paolo, Di Fruscia, Christopher R, Reynolds, David T, Dexter, Michael J E, Sternberg, Eric W-F, Lam, Clemens, Steegborn, Matthew J, Fuchter
Publikováno v:
Journal of Medicinal Chemistry
Sirtuins (SIRTs) are NAD-dependent deacylases, known to be involved in a variety of pathophysiological processes and thus remain promising therapeutic targets for further validation. Previously, we reported a novel thienopyrimidinone SIRT2 inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b21de68a90e9d8619a1f335bd7ea96c
https://pubmed.ncbi.nlm.nih.gov/28135086
https://pubmed.ncbi.nlm.nih.gov/28135086