Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Michael J. Cronce"'
Autor:
Anna Herland, Ben Swenor, Daniel Levner, Olivier Y.F. Henry, Sasan Jalili-Firoozinezhad, Angeliki Chalkiadaki, Henry Sanchez, Andrzej Przekwas, Sauveur S. F. Jeanty, Rachelle Prantil-Baun, Josiah Sliz, Youngjae Choe, Kyung-Jin Jang, Moran Yadid, Susan Marquez, Chris Hinojosa, Thomas C. Ferrante, Blakely B. O'Connor, Tiama Hamkins-Indik, Rachel Fleming, Stephanie Dauth, Janna Nawroth, Morgan Burt, Ben M. Maoz, David B. Chou, Aaron Delahanty, John P. Ferrier, Anthony Bahinski, Jose Fernandez-Alcon, Bret Nestor, Guy Robert Thompson, Lian Leng, Robert Mannix, Michael J. Cronce, Yuka Milton, Mahadevabharath R. Somayaji, Alexandra Sontheimer-Phelps, Tae-Eun Park, Miles Ingram, Edward A. FitzGerald, Debarun Das, Ville J. Kujala, Josue A. Goss, George J. Touloumes, Toni Divic, Carlos F. Ng, Oren Levy, Zachary Tranchemontagne, Elizabeth Calamari, Geraldine A. Hamilton, Alexander Cho, Thomas Grevesse, Norman Wen, Tessa Huffstater, Donald E. Ingber, Kevin Kit Parker, Richard M. Novak
Publikováno v:
Nature Biomedical Engineering. 4:407-420
Organ chips can recapitulate organ-level (patho)physiology, yet pharmacokinetic and pharmacodynamic analyses require multi-organ systems linked by vascular perfusion. Here, we describe an 'interrogator' that employs liquid-handling robotics, custom s
Autor:
David B. Chou, Rachelle Prantil-Baun, Ben Swenor, Sasan Jalili-Firoozinezhad, Andrzej Przekwas, Susan Marquez, Tessa Huffstater, Donald E. Ingber, Ben M. Maoz, Anna Herland, Michael J. Cronce, Yuka Milton, Angeliki Chalkiadaki, Miles Ingram, Mahadevabharath R. Somayaji, Alexandra Sontheimer-Phelps, Oren Levy, Sauveur S. F. Jeanty, Richard M. Novak, Aaron Delahanty, Kevin Kit Parker, Debarun Das
Publikováno v:
Nature Biomedical Engineering. 4:421-436
Analyses of drug pharmacokinetics (PKs) and pharmacodynamics (PDs) performed in animals are often not predictive of drug PKs and PDs in humans, and in vitro PK and PD modelling does not provide quantitative PK parameters. Here, we show that physiolog
Autor:
Olive Mwizerwa, Renea Faulknor, Michael J. Cronce, Xiang-Hong Liu, Emmanuel C. Ekwueme, Craig M. Neville, Irina Pomerantseva, Scott M. Goldman, Cathryn A. Sundback
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 106:716-725
Biological surgical scaffolds are used in plastic and reconstructive surgery to support structural reinforcement and regeneration of soft tissue defects. Macrophage and fibroblast cell populations heavily regulate scaffold integration into host tissu
Autor:
Remi Villenave, Donald E. Ingber, Michael J. Cronce, William D. Leineweber, Maximilian A. Benz, Olivier Y.F. Henry
Publikováno v:
Lab on a Chip. 17:2264-2271
Trans-Epithelial Electrical Resistance (TEER) is broadly used as an experimental readout and a quality control assay for measuring the integrity of epithelial monolayers cultured under static conditions in vitro, however, there is no standard methodo
Autor:
Ben M. Maoz, Sasan Jalili-Firoozinezhad, Andrzej Przekwas, Carlos F. Ng, Alexander Cho, Anna Herland, Jose Fernandez-Alcon, Daniel Levner, Olivier Y.F. Henry, Janna Nawroth, Blakely B. O'Connor, Debarun Das, David B. Chou, Kevin Kit Parker, Anthony Bahinski, Morgan Burt, Ville J. Kujala, Susan Clauson, Mahadevabharath R. Somayaji, Thomas C. Ferrante, Ben Swenor, Henry Sanchez, Lian Leng, Tessa Huffstater, Angeliki Chalkiadaki, Miles Ingram, Donald E. Ingber, Tiama Hamkins-Indik, Norman Wen, Rachelle Prantil-Baun, Youngjae Choe, Josiah Sliz, Zachary Tranchemontagne, Bret Nestor, George J. Touloumes, Rachel Fleming, Guy Robert Thompson, Alexandra Sontheimer-Phelps, Josue A. Goss, Oren Levy, Toni Divic, Elizabeth Calamari, Sauveur S. F. Jeanty, Kyung-Jin Jang, Michael J. Cronce, Yuka Milton, Richard M. Novak, Geraldine A. Hamilton, Thomas Grevesse, Chris Hinojosa, Moran Yadid, Stephanie Dauth, John P. Ferrier, Tae-Eun Park, Robert Mannix, Edward A. FitzGerald, Aaron Delahanty
Publikováno v:
Nat Biomed Eng
Here we describe of an ‘Interrogator’ instrument that uses liquid-handling robotics, a custom software package, and an integrated mobile microscope to enable automated culture, perfusion, medium addition, fluidic linking, sample collection, andin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91904c828996f1d91cb14b8c52e98514
https://doi.org/10.1101/569541
https://doi.org/10.1101/569541
Autor:
Marinke van der Helm, Mathieu Odijk, Andries D. van der Meer, Olivier Y.F. Henry, Donald E. Ingber, Jan C.T. Eijkel, Amir Bein, William D. Leineweber, Loes I. Segerink, Tiama Hamkins-Indik, Albert van den Berg, Michael J. Cronce
Publikováno v:
Lab on a Chip
Lab on a chip, 19(3), 452-463. Royal Society of Chemistry
Lab on a chip, 19(3), 452-463. Royal Society of Chemistry
Here, we describe methods for combining impedance spectroscopy measurements with electrical simulation to reveal transepithelial barrier function and tissue structure of human intestinal epithelium cultured inside an organ-on-chip microfluidic cultur
Autor:
Michael J. Cronce, Diogo M. Camacho, Alessio Tovaglieri, Cicely W. Fadel, Elizabeth Calamari, David T. Breault, Oren Levy, Richard M. Novak, Cabral Jms, Dennis L. Kasper, Donald E. Ingber, Francesca S. Gazzaniga, Sasan Jalili-Firoozinezhad, Bret Nestor, Katherine E. Gregory
The diverse bacterial populations that comprise the commensal microbiota of the human intestine play a central role in health and disease, yet no method is available to sustain these complex microbial communities in direct contact with living human i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0599728c5b03a1a943e8002f01e3fc59
https://doi.org/10.1101/421404
https://doi.org/10.1101/421404
Autor:
Elizabeth Calamari, Sasan Jalili-Firoozinezhad, Richard M. Novak, Oren Levy, Ben Swenor, Bret Nestor, Amir Bein, Alessio Tovaglieri, Cicely W. Fadel, David T. Breault, Dennis L. Kasper, Francesca S. Gazzaniga, Katherine E. Gregory, Donald E. Ingber, Diogo M. Camacho, Joaquim M. S. Cabral, Michael J. Cronce
Publikováno v:
Nature biomedical engineering. 3(7)
The diverse bacterial populations that comprise the commensal microbiome of the human intestine play a central role in health and disease. A method that sustains complex microbial communities in direct contact with living human intestinal cells and t
Autor:
Cathryn A. Sundback, Michael J. Cronce, Mark A. Randolph, Alan Tseng, Joseph P. Vacanti, Anya M. Kimura, Craig M. Neville, Irina Pomerantseva
Publikováno v:
Cartilage
Objective Our goal was to engineer cartilage in vivo using auricular chondrocytes that underwent clinically relevant expansion and using methodologies that could be easily translated into health care practice. Design Sheep and human chondrocytes were
Autor:
Francesca S. Gazzaniga, Michael J. Cronce, Sasan Jalili-Firoozinezhad, David T. Breault, Oren Levy, Diogo M. Camacho, Alessio Tovaglieri, Ben Swenor, Joaquim M. S. Cabral, Elizabeth Calamari, Richard M. Novak, Dennis L. Kasper, Donald E. Ingber, Bret Nestor, Katherine E. Gregory, Cicely W. Fadel, Amir Bein
Publikováno v:
Nat Biomed Eng
In the version of this Article originally published, the authors mistakenly cited Fig. 5d in the sentence beginning ‘Importantly, the microbiome cultured in these primary Intestine Chips...’; the correct citation is Supplementary Table 2. This ha