Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Michael J. Cobb"'
Publikováno v:
IEEE Journal of Selected Topics in Quantum Electronics. 13:1596-1601
Microendoscope is a critical technology to enable high-resolution imaging of internal luminal organs with optical coherence tomography. This paper reports the development of an achromatic compound microlens and a rapid scanning microendoscope based o
Publikováno v:
Cancer Biomarkers. 2:163-173
Improved diagnostics capable of non-invasive detection of early stage carcinogenesis would benefit basic research, and potentially aid in clinical cancer diagnosis and management. The two-stage carcinogenesis protocol is widely used for studying the
Publikováno v:
Clinical Gastroenterology and Hepatology. 3:S49-S52
A novel, high-resolution, needle-based optical coherence tomography (OCT) device for improving the ability to detect early epithelial dysplasia in solid tissues/organs in vivo is currently in development. An instrument capable of real-time imaging of
Autor:
Xingde Li, Leslie Au, Hu Cang, Jingyi Chen, Michael J. Cobb, Zhi-Yuan Li, Benjamin J. Wiley, Fusayo Saeki, Younan Xia, Hui Zhang, Michael B. Kimmey
Publikováno v:
Nano Letters. 5:473-477
Gold nanocages of40 nm in dimension have been synthesized using the galvanic replacement reaction between Ag nanocubes and HAuCl4 in an aqueous solution. By controlling the molar ratio between Ag and HAuCl4, the gold nanocages could be tuned to displ
Publikováno v:
Optics express. 13(20)
We describe a generic method to optimize the optical spectral throughput of a pair of acousto-optic modulators (AOM) which can be used for introducing a frequency shift in ultrahigh-resolution heterodyne optical coherence tomography. Systematic and q
Autor:
Li Huo, Desheng Zheng, Tae Hee Kim, Xingde Li, Joo Ha Hwang, Yongping Chen, Yicong Wu, Jiefeng Xi, Michael J. Cobb, Suzie H. Pun
Publikováno v:
2009 IEEE/NIH Life Science Systems and Applications Workshop.
This paper reports on our recent development of two-types of all-fiber-optic scanning endomicroscopy technologies for high-resolution optical imaging of internal organs. The first one is an OCT balloon catheter technology that permits systematic imag
Autor:
Joo Ha Hwang, Melissa P. Upton, Brant K. Oelschlager, Douglas E. Wood, Xingde Li, Michael J. Cobb, Yuchuan Chen, Michael B. Kimmey
Publikováno v:
Gastrointestinal endoscopy. 71(2)
Background Optical coherence tomography (OCT) is being developed as a potentially valuable method for high-resolution cross-sectional imaging of the esophageal mucosal and submucosal layers. One potential application of OCT imaging is to identify sub
Publikováno v:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2008
A flexible fiber-optic endomicroscopy system was developed for nonlinear optical imaging of biological samples. Double-clad fiber and photonic bandgap fiber were employed in the endomicroscope for femtosecond pulse delivery, dispersion compensation,
Publikováno v:
Conference on Lasers and Electro-Optics/International Quantum Electronics Conference.
An endomicroscope with enhanced signal collection efficiency was developed using customized double-clad fiber and aspherical compound-lens. Ex vivo two-photon fluorescence imaging of epithelial tissues was demonstrated for the first time with an all-
Publikováno v:
Biomedical Optics.
We show that spectral-domain optical coherence tomography can monitor blood flow in and around the wound bed during the cutaneous wound healing process in a mouse model.