Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Michael J. Cipriano"'
Autor:
Anat Florentin, David W. Cobb, Jillian D. Fishburn, Michael J. Cipriano, Paul S. Kim, Manuel A. Fierro, Boris Striepen, Vasant Muralidharan
Publikováno v:
Cell Reports, Vol 21, Iss 7, Pp 1746-1756 (2017)
Summary: The deadly malaria parasite Plasmodium falciparum contains a nonphotosynthetic plastid, known as the apicoplast, that functions to produce essential metabolites, and drugs that target the apicoplast are clinically effective. Several prokaryo
Externí odkaz:
https://doaj.org/article/0f3599c3e4b7484ba41d8cb4b81500a6
Publikováno v:
mBio, Vol 8, Iss 3 (2017)
ABSTRACT Apicomplexan parasites cause a variety of important infectious diseases, including malaria, toxoplasma encephalitis, and severe diarrhea due to Cryptosporidium. Most apicomplexans depend on an organelle called the apicoplast which is derived
Externí odkaz:
https://doaj.org/article/6c5f476588964f2392f13d54fb255032
Autor:
Maude F. Lévêque, Laurence Berry, Michael J. Cipriano, Hoa-Mai Nguyen, Boris Striepen, Sébastien Besteiro
Publikováno v:
mBio, Vol 6, Iss 6 (2015)
ABSTRACT Autophagy is a catabolic process widely conserved among eukaryotes that permits the rapid degradation of unwanted proteins and organelles through the lysosomal pathway. This mechanism involves the formation of a double-membrane structure cal
Externí odkaz:
https://doaj.org/article/677d0c1f546e4c2da1ccfd48aca86707
Autor:
Michael J. Cipriano, Umaer Khan, Terry K. Smith, Peter J. Bush, Stephen L. Hajduk, Aakash Sur, Peter J. Myler, Jacquelyn R McDonald, Paige Garrison, James D. Bangs
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
mBio
mBio
This work was supported by United States Public Health Service grant R01 AI035739 and funds from the Jacobs School of Medicine and Biomedical Sciences to J.D.B. and from United States Public Health Service grant 1S10OD021719-01A1 to the University of
Autor:
Allan L. Chen, Marjorie Maynadier, Boris Striepen, Michael J. Cipriano, Laurence Berry-Sterkers, Catherine Suarez, Peter J. Bradley, Gaelle Lentini, Eleonora Aquilini, Martin J. Boulanger, Raghavendran Ramaswamy, Maryse Lebrun
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Members of the Apicomplexa phylum, including Plasmodium and Toxoplasma, have two types of secretory organelles (micronemes and rhoptries) whose sequential release is essential for invasion and the intracellular lifestyle of these eukaryotes. During i
Autor:
Barbara J Davids, David S Reiner, Shanda R Birkeland, Sarah P Preheim, Michael J Cipriano, Andrew G McArthur, Frances D Gillin
Publikováno v:
PLoS ONE, Vol 1, p e44 (2006)
Since the Giardia lamblia cyst wall is necessary for survival in the environment and host infection, we tested the hypothesis that it contains proteins other than the three known cyst wall proteins. Serial analysis of gene expression during growth an
Externí odkaz:
https://doaj.org/article/2961da6c476e4f1facbd079c6ec13eac
Autor:
Paul S Kim, Anat Florentin, Michael J. Cipriano, Manuel A. Fierro, Boris Striepen, Jillian D Fishburn, David W. Cobb, Vasant Muralidharan
Publikováno v:
Cell Reports, Vol 21, Iss 7, Pp 1746-1756 (2017)
Summary: The deadly malaria parasite Plasmodium falciparum contains a nonphotosynthetic plastid, known as the apicoplast, that functions to produce essential metabolites, and drugs that target the apicoplast are clinically effective. Several prokaryo
Autor:
Michael J. Cipriano, Stephen L. Hajduk
Publikováno v:
Essays in biochemistry. 62(2)
Extracellular vesicles (EVs) are produced by invading pathogens and also by host cells in response to infection. The origin, composition, and function of EVs made during infection are diverse and provide effective vehicles for localized and broad dis
Autor:
Yael Bar-Peled, Caleb J. Studstill, Adam Sateriale, Sumiti Vinayak, Boris Striepen, Mattie C. Pawlowic, Carrie F. Brooks, Michael J. Cipriano
Publikováno v:
Nature
Recent studies into the global causes of severe diarrhoea in young children have identified the protozoan parasite Cryptosporidium as the second most important diarrhoeal pathogen after rotavirus. Diarrhoeal disease is estimated to be responsible for
Autor:
Simon E. Prochnik, Chandler Fulton, Scott C. Dawson, Hank Tu, Michael J. Cipriano, Joel B. Dacks, Alan Kuo, Joel Mancuso, Shengqiang Shu, W. Zacheus Cande, Igor V. Grigoriev, Alexander R. Paredez, Lillian K. Fritz-Laylin, Susan Lucas, Mark C. Field, Erika Lindquist, Daniel S. Rokhsar, Meredith L. Carpenter, Asaf Salamov, Rochak Neupane, Harris Shapiro, Jarrod Chapman, Michael L. Ginger, Jonathan K Pham
Publikováno v:
Cell. 140(5):631-642
SummaryGenome sequences of diverse free-living protists are essential for understanding eukaryotic evolution and molecular and cell biology. The free-living amoeboflagellate Naegleria gruberi belongs to a varied and ubiquitous protist clade (Heterolo