Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Michael J. Bruno"'
Publikováno v:
Biotechnology Progress. 37
Yersiniabactin (Ybt) is a hybrid polyketide-nonribosomal complex natural product also known as a siderophore for its iron chelation properties. The native producer of Ybt, Yersinia pestis, is a priority pathogen responsible for the plague in which th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e02b6100cd6756d5a7a88eafa777d5e
https://doi.org/10.1002/btpr.3103
https://doi.org/10.1002/btpr.3103
Autor:
Ajay N. Baindur, Michael J. Bruno, Jinwoo Park, Kathryn A. Hausknecht, Rohan V. Bhimani, Samir Haj-Dahmane, Roh-Yu Shen, Malte Feja, Caroline E. Bass, Ken T. Wakabayashi
Publikováno v:
Neuropsychopharmacology. 44:372-380
Cues predicting rewards can gain motivational properties and initiate reward-seeking behaviors. Dopamine projections from the ventral tegmental area (VTA) to the nucleus accumbens (NAc) are critical in regulating cue-motivated responding. Although, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b60f62346d81bfc671fc5367dee015f
https://doi.org/10.1038/s41386-018-0097-6
https://doi.org/10.1038/s41386-018-0097-6
Publikováno v:
The Analyst. 141:3746-3755
The olfactory tubercle (OT), as a component of the ventral striatum, serves as an important multisensory integration center for reward-related processes in the brain. Recent studies show that dense dopaminergic innervation from the ventral tegmental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722db41fb085fc5861ce9a32cffb02cb
https://doi.org/10.1039/c6an00196c
https://doi.org/10.1039/c6an00196c
Autor:
Erik B. Oleson, Allyn C. Howlett, Michael J. Bruno, Evgeny A. Budygin, Caroline E. Bass, Yun Beom Lee, Lawrence C. Blume, Alexis C. Thompson
Publikováno v:
Frontiers in Behavioral Neuroscience
Recent studies have used conditional knockout mice to selectively delete the D2 autoreceptor; however, these approaches result in global deletion of D2 autoreceptors early in development. The present study takes a different approach using RNA interfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd6c762823a603c8316c7367144f538
Publikováno v:
Faraday Discuss.. 161:461-480
Poly-unsaturated fatty acids (PUFAs) alter the function of many membrane proteins, whereas monounsatured fatty acids generally are inert. We previously showed that docosahexaenoic acid (DHA) at pH 7 decreases the bilayer stiffness, consistent with an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56392c902d4991d10a704c791aa647d0
https://doi.org/10.1039/c2fd20092a
https://doi.org/10.1039/c2fd20092a
Although the importance of a SNARE complex in neurotransmitter release is widely accepted, there exist different views on how the complex promotes fusion. One hypothesis is that the SNARE complex’s ability to bring membranes into contact is suffici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa09dad5f0c2cd1c43ec9082989db7df
Autor:
Henry J. Pernicka, Michael J. Bruno
Publikováno v:
Journal of Spacecraft and Rockets. 42:902-912
Constellations of satellites in Tundra orbits provide an innovative alternative to the increasingly crowded geostationary orbit belt. The Tundra constellation uses three or more spacecraft in inclined geosynchronous orbits. The nominal orbit design f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12b69971b630b07088c1f69bb6344587
https://doi.org/10.2514/1.7765
https://doi.org/10.2514/1.7765
Autor:
Sonya E. Tape, Rikke Søgaard, Olaf S. Andersen, Gwendolyn L. Mattice, Claus Helix Nielsen, Michael J. Bruno, P. Birn, Anker Jon Hansen, Jan Egebjerg, Denise V. Greathouse, Jens A. Lundbæk, Jeffrey Girshman, Roger E. Koeppe
Publikováno v:
The Journal of General Physiology
Membrane proteins are regulated by the lipid bilayer composition. Specific lipid–protein interactions rarely are involved, which suggests that the regulation is due to changes in some general bilayer property (or properties). The hydrophobic coupli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ec3486343a3bc765ff94a02f353fb0
http://europepmc.org/articles/PMC2234500
http://europepmc.org/articles/PMC2234500
Publikováno v:
Biophysical journal. 102(12)
Membrane fusion, essential to eukaryotic life, is broadly envisioned as a three-step process proceeding from contacting bilayers through two semistable, nonlamellar lipidic intermediate states to a fusion pore. Here, we introduced a new, to our knowl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d5a9af8322446fd8f67b6e65a829d7
https://pubmed.ncbi.nlm.nih.gov/22735525
https://pubmed.ncbi.nlm.nih.gov/22735525
Autor:
Michael J. Bruno, Barry R. Lentz
Publikováno v:
Biophysical Journal. 100(3)
During neurotransmitter release, curved synaptic vesicles fuse with the un-curved pre-synaptic plasma membrane, leading to the merger of two lipid bilayers and the release of neurotransmitters, a process that requires SNARE proteins in both membranes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30f9112057f8d89981cc1a0a610b99e