Zobrazeno 1 - 7
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pro vyhledávání: '"Michael J. Bonaduce"'
Autor:
Michael J. Bonaduce, Amar J. S. Klar
Publikováno v:
Chromosome Research. 21:297-309
The base complementarity feature (Watson and Crick in Nature 171(4356):737–738, 1953) and the rule of semi-conservative mode of DNA replication (Messelson and Stahl in Proc Natl Acad Sci U S A 44:671–682, 1958) dictate that two identical replicas
Defining the epigenetic mechanism of asymmetric cell division of Schizosaccharomyces japonicus yeast
Publikováno v:
Genetics
A key question in developmental biology addresses the mechanism of asymmetric cell division. Asymmetry is crucial for generating cellular diversity required for development in multicellular organisms. As one of the potential mechanisms, chromosomally
Publikováno v:
Genetics. 191(1)
A novel mating-type switching-defective mutant showed a highly unstable rearrangement at the mating-type locus (mat1) in fission yeast. The mutation resulted from local amplification of a 134-bp DNA fragment by the mat1-switching phenomenon. We specu
Publikováno v:
Genetics. 190(3)
Schizosaccharomyces pombe, the fission yeast, cells alternate between P- and M-mating type, controlled by the alternate alleles of the mating-type locus (mat1). The mat1 switching occurs by replacing mat1 with a copy derived from a silenced “donor
Autor:
Klavs R. Hansen, Gurjeet Singh, Geneviève Thon, Deepak Sidhu, Amar J. S. Klar, Michael J. Bonaduce, Susagna Padrissa Altes, Janne Verhein-Hansen
Publikováno v:
Genetics. 171(4)
Fission yeast heterochromatin is formed at centromeres, telomeres, and in the mating-type region where it mediates the transcriptional silencing of the mat2-P and mat3-M donor loci and the directionality of mating-type switching. We conducted a genet
Position-effect control at the silent mat2-mat3 interval and at centromeres and telomeres in fission yeast is suggested to be mediated through the assembly of heterochromatin-like structures. Therefore, trans-acting genes that affect silencing may en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edbbee42126389bf1f4e6d58f9b7682a
https://europepmc.org/articles/PMC1460350/
https://europepmc.org/articles/PMC1460350/
Publikováno v:
Nature genetics. 19(2)
Heritable inactivation of specific regions of the genome is a widespread, possibly universal phenomenon for gene regulation in eukaryotes. Self-perpetuating, clonally inherited chromatin structure has been proposed as the explanation for such phenome