Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michael J. Bickerdike"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Glioblastoma is an aggressive brain cancer, usually of unknown etiology, and with a very poor prognosis. Survival from diagnosis averages only 3 months if left untreated and this only increases to 12–15 months upon treatment. Tr
Externí odkaz:
https://doaj.org/article/222c2913c9164cf8b68cb094bfbedce6
Autor:
Ivaylo V. Dimitrov, Martyn G. Harvey, Logan J. Voss, James W. Sleigh, Michael J. Bickerdike, William A. Denny
Publikováno v:
Molecules, Vol 25, Iss 12, p 2950 (2020)
A series of benzene ring substituted ketamine N-alkyl esters were prepared from the corresponding substituted norketamines. Few of the latter have been reported since they have not been generally accessible via known routes. We report a new general r
Externí odkaz:
https://doaj.org/article/9e9cb9e271fb4f0b893a650b6528e6c1
Autor:
Ivaylo Dimitrov, Logan J. Voss, Michael J. Bickerdike, James W. Sleigh, Martyn Harvey, William A. Denny
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:1226-1231
N-Aliphatic ester analogues of the non-opioid ketamine (1) retain effective anaesthetic/analgesic properties while minimising ketamine's psychomimetic side-effects. We show that the anaesthetic/analgesic properties of these ester analogues depend cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41cfbb9bfd03258ef957026dac01fe59
https://doi.org/10.1016/j.bmc.2019.02.010
https://doi.org/10.1016/j.bmc.2019.02.010
Autor:
Frank Sieg, Michael J. Bickerdike, Ernest Stephen Sirimanne, Margaret A. Brimble, Gregory Brian Thomas, Peter David Gluckman, Hai Lin, Wing Leong, David Charles Batchelor, Jingyuan Wen, Paul W. R. Harris
Publikováno v:
Journal of the neurological sciences. 278(1-2)
The N-terminal cleavage product of human insulin-like growth factor-1 (IGF-1) in the brain is the tripeptide molecule Glypromate ® (Gly–Pro–Glu). Glypromate ® has demonstrated neuroprotective effects in numerous in vitro and in vivo models of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3dddcb28587577d439e7f5f9a20e85
https://pubmed.ncbi.nlm.nih.gov/19157421
https://pubmed.ncbi.nlm.nih.gov/19157421
Publikováno v:
Neuroreport. 10(1)
Behavioral sensitization to chronic amphetamine develops in parallel with an enhancement of amphetamine-stimulated efflux of acetylcholine (ACh) in striatum. The present study investigated the role of NMDA receptors in the latter phenomenon. Rats wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c375f1e7a3545b25c4c68c9c129528
https://pubmed.ncbi.nlm.nih.gov/10094137
https://pubmed.ncbi.nlm.nih.gov/10094137
Publikováno v:
Schizophrenia Research. 24:73
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bab0c9925d57059af1c9aa2e961785e6
https://doi.org/10.1016/s0920-9964(97)82197-4
https://doi.org/10.1016/s0920-9964(97)82197-4