Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Michael J Wedemeyer"'
Autor:
Christian Berg, Michael J Wedemeyer, Motiejus Melynis, Roman R Schlimgen, Lasse H Hansen, Jon Våbenø, Francis C Peterson, Brian F Volkman, Mette M Rosenkilde, Hans R Lüttichau
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010355 (2022)
Human cytomegalovirus (HCMV) is a major pathogen in immunocompromised patients. The UL146 gene exists as 14 diverse genotypes among clinical isolates, which encode 14 different CXC chemokines. One genotype (vCXCL1GT1) is a known agonist for CXCR1 and
Externí odkaz:
https://doaj.org/article/b58f3e9f294b4bb682ffd33432ab9a5c
Autor:
Michael J. Wedemeyer, Elaine M. Jennings, Hudson R. Smith, Teresa S. Chavera, Raehannah J. Jamshidi, Kelly A. Berg, William P. Clarke
Publikováno v:
Neuropharmacology. 220
Long-term inhibition of kappa opioid receptor (KOR) signaling in peripheral pain-sensing neurons is a potential obstacle for development of peripherally-restricted KOR agonists that produce analgesia. Such a long-term inhibitory mechanism is invoked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc04a03c2e42fe28c0632aef9193591
https://pubmed.ncbi.nlm.nih.gov/36126728
https://pubmed.ncbi.nlm.nih.gov/36126728
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b931fe2b10608a66ca131f4c8b742f3a
https://doi.org/10.1096/fasebj.2022.36.s1.l7464
https://doi.org/10.1096/fasebj.2022.36.s1.l7464
Autor:
Kyler S. Crawford, Anthony E. Getschman, Sarah A. Mahn, John D. McCorvy, Adriano Marchese, Brian F. Volkman, Francis C. Peterson, Michael J. Wedemeyer
Publikováno v:
J Biol Chem
The human chemokine family consists of 46 protein ligands that induce chemotactic cell migration by activating a family of 23 G protein–coupled receptors. The two major chemokine subfamilies, CC and CXC, bind distinct receptor subsets. A sequence m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef22d7126a36b0876f830090ed17953
https://doi.org/10.1074/jbc.ra120.014244
https://doi.org/10.1074/jbc.ra120.014244
Publikováno v:
Biochem Biophys Res Commun
Chemokine receptors are a subset of G protein-coupled receptors defined by the distinct property of binding small protein ligands in the chemokine family. Chemokine receptors recognize their ligands by a mechanism that is distinct from other class A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d797d8fd80ab6774e67c642533c0499b
https://doi.org/10.1016/j.bbrc.2019.12.076
https://doi.org/10.1016/j.bbrc.2019.12.076
Autor:
Wujie Zhang, Junhong Chen, Alexander Dyble, Douglas A. Steeber, Rebecca L. Majewski, Kendra Lehman, M. Kaltchev, Xiaoru Guo, Michael J. Wedemeyer, Samuel Stealey
Publikováno v:
Pharmaceutical Development and Technology. 25:260-265
Pectin-based hydrogel microcarriers have shown promise for drug delivery to the colonic region. Microcarriers must remain stable throughout the upper gastrointestinal tract for effective colonic delivery, an issue that traditional pectin-based microc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccbe201bdeac00d041935bb9d3a9437
https://doi.org/10.1080/10837450.2019.1691591
https://doi.org/10.1080/10837450.2019.1691591
Autor:
Jeanie K. Meckes, Michael J. Wedemeyer, Eva E. Redei, L. C. Solberg Woods, Riyan Cheng, Hong He, A. Kastner, Stephanie L. Wert, Katie Holl, Abraham A. Palmer, L. Clopton
Publikováno v:
Genes, Brain and Behavior. 17:139-148
Major depressive disorder (MDD) is a complex illness caused by both genetic and environmental factors. Antidepressant resistance also has a genetic component. To date, however, very few genes have been identified for major depression or antidepressan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb49aa576fb24fbac50cd3a8734a8e95
https://doi.org/10.1111/gbb.12410
https://doi.org/10.1111/gbb.12410
Chemokines are soluble, secreted proteins that induce chemotaxis of leukocytes and other cells. Migratory cells can sense the chemokine concentration gradient following chemokine binding and activation of chemokine receptors, a subset of the G protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5bba81e203b27b7328c6f88578d483
https://doi.org/10.1016/bs.mcb.2018.09.005
https://doi.org/10.1016/bs.mcb.2018.09.005
Autor:
Michael J. Wedemeyer, Zachary R. Paquin, Gerardo Rubio, Logan R. Readnour, Xiaoru Guo, Joshua N. Clausen, Brock E. Shilling, Ryan P. Dohn, Anna C. O’Donnell, Jung C. Lee, Emily N. Dufner, Junhong Chen, Ian J Pavelich, Wujie Zhang, Tyler F. Brown, Alec L. Polovchak, Emily S. Savela, Charles S Tritt, Matthew J. Bissen, Samantha J. Fredricks, M. Kaltchev
Publikováno v:
The International Journal of Artificial Organs. 39:518-523
Purpose To improve the stability of pectin-oligochitosan hydrogel microcapsules under physiological conditions. Methods Two different approaches were examined: change of the cross-linker length and treatment of the hydrogel microcapsules with 150 Mm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1427f6f1e65f7791e7009b8b7f5ee68d
https://doi.org/10.5301/ijao.5000532
https://doi.org/10.5301/ijao.5000532