Výsledky vyhledávání - "Michael J Wald"

Cerebral Edema in Patients With Large Hemispheric Infarct Undergoing Reperfusion Treatment A HERMES Meta-Analysis

Publikováno v: Stroke
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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Stroke, 52(11), 3450-3458. Lippincott Williams & Wilkins
Stroke, 3450-3458. Lippincott Williams and Wilkins
STARTPAGE=3450;ENDPAGE=3458;ISSN=0039-2499;TITLE=Stroke

Background and Purpose: Whether reperfusion into infarcted tissue exacerbates cerebral edema has treatment implications in patients presenting with extensive irreversible injury. We investigated the effects of endovascular thrombectomy and reperfusio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c900106d6a56254514d57602b511820e
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=1899

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Safety and efficacy of anti-tau monoclonal antibody gosuranemab in progressive supranuclear palsy: a phase 2, randomized, placebo-controlled trial

Publikováno v: Nature medicine 27(8), 1451-1457 (2021). doi:10.1038/s41591-021-01455-x
Nature medicine, vol 27, iss 8

A randomized, double-blind, placebo-controlled, 52-week study (no. NCT03068468) evaluated gosuranemab, an anti-tau monoclonal antibody, in the treatment of progressive supranuclear palsy (PSP). In total, 486 participants dosed were assigned to either

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fe1078c6e1b9326ff9a1875799321f
https://pubmed.ncbi.nlm.nih.gov/36253611

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Automated Calculation of Alberta Stroke Program Early CT Score: Validation in Patients With Large Hemispheric Infarct

Autor: Michael Mlynash, Michael J Wald, Andreas Maier, Juergen Endres, Bradley J. Molyneaux, Matus Straka, Gregory W. Albers, Roland Bammer, Kevin N. Sheth, W. Taylor Kimberly, Holly E. Hinson

Publikováno v: Stroke. 50(11)

Background and Purpose— We compared the Alberta Stroke Program Early CT Score (ASPECTS), calculated using a machine learning-based automatic software tool, RAPID ASPECTS, as well as the median score from 4 experienced readers, with the diffusion-we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b0915e7821e86fedfffa844046019a
https://pubmed.ncbi.nlm.nih.gov/31500555

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Predicting trabecular bone elastic properties from measures of bone volume fraction and fabric on the basis of micromagnetic resonance images

Autor: Jeremy F. Magland, Yusuf A. Bhagat, Michael J. Wald, Felix W. Wehrli, Chamith S. Rajapakse

Publikováno v: Magnetic Resonance in Medicine. 68:463-473

The relationship between fabric (a measure of structural anisotropy) and elastic properties of trabecular bone was examined by invoking morphology and homogenization theory on the basis of micromagnetic resonance images from the distal tibia in speci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9a3ffb7ca034b205fa1588cf9172efe
https://doi.org/10.1002/mrm.23253

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On the Significance of Motion Degradation in High-resolution 3D μMRI of Trabecular Bone

Autor: Jeremy F. Magland, Felix W. Wehrli, Michael J. Wald, Hee Kwon Song, Chamith S. Rajapakse, Mary B. Leonard, Yusuf A. Bhagat

Publikováno v: Academic Radiology. 18:1205-1216

Subtle subject movement during high-resolution three-dimensional micro-magnetic resonance imaging of trabecular bone (TB) causes blurring, thereby rendering the data unreliable for quantitative analysis. In this work, the effects of translational and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f8288c5b245d649e3439fc87d5c183
https://doi.org/10.1016/j.acra.2011.06.006

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Reduced bone mineral density is not associated with significantly reduced bone quality in men and women practicing long-term calorie restriction with adequate nutrition

Autor: Michael Kleerekoper, Luigi Fontana, John J. Kotyk, Reina Armamento-Villareal, Dennis T. Villareal, Venkata Kenguva, Pamela Seaman, Allon Shahar, Michael J. Wald

Publikováno v: Aging Cell. 10:96-102

Calorie restriction (CR) reduces bone quantity but not bone quality in rodents. Nothing is known regarding the long-term effects of CR with adequate intake of vitamin and minerals on bone quantity and quality in middle-aged lean individuals. In this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d05a598f5eafb34d161aabc2a6e02b69
https://doi.org/10.1111/j.1474-9726.2010.00643.x

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Computational biomechanics of the distal tibia from high-resolution MR and micro-CT images

Autor: X. Henry Zhang, Jeremy F. Magland, X. Sherry Liu, Michael J. Wald, X. Edward Guo, Felix W. Wehrli, Chamith S. Rajapakse

Publikováno v: Bone. 47:556-563

The mechanical properties of bone estimated by micro-finite element (microFE) analysis on the basis of in vivo micro-MR images (microMRIs) of the distal extremities provide a new tool for direct assessment of the mechanical consequences of interventi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d31027b7d9999e45182b1939f11a59d
https://doi.org/10.1016/j.bone.2010.05.039

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Accuracy of high-resolution in vivo micro magnetic resonance imaging for measurements of microstructural and mechanical properties of human distal tibial bone

Autor: Chamith S. Rajapakse, X. Henry Zhang, X. Sherry Liu, Jeremy F. Magland, Felix W. Wehrli, Michael J. Wald, Mark F Adam, Paul Sajda, Kiranjit K Sekhon, X. Edward Guo

Publikováno v: Journal of Bone and Mineral Research. 25:2039-2050

Micro magnetic resonance imaging (µMRI) is an in vivo imaging method that permits 3D quantification of cortical and trabecular bone microstructure. µMR images can also be used for building microstructural finite element (µFE) models to assess bone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197d71a3c7c57fa23ebbcc21fad537b6
https://doi.org/10.1002/jbmr.92

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Spin-echo micro-MRI of trabecular bone using improved 3D fast large-angle spin-echo (FLASE)

Autor: Jeremy F. Magland, Michael J. Wald, Felix W. Wehrli

Publikováno v: Magnetic Resonance in Medicine. 61:1114-1121

Fast Large-Angle Spin Echo (FLASE) is a common pulse sequence designed for quantitative imaging of trabecular bone micro-architecture. However, imperfections in the nonselective phase-reversal pulse render it prone to stimulated echo artifacts. The p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28c5bddc25ab5cc1007a6cf5db962adf
https://doi.org/10.1002/mrm.21905

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Trabecular Structure Quantified With the MRI-Based Virtual Bone Biopsy in Postmenopausal Women Contributes to Vertebral Deformity Burden Independent of Areal Vertebral BMD

Autor: Michael J. Wald, Andra M Popescu, Alexander C. Wright, Branimir Vasilic, Babette S. Zemel, Hee Kwon Song, Louise Loh, Punam K. Saha, Peter J. Snyder, Glenn A. Ladinsky, Felix W. Wehrli

Publikováno v: Journal of Bone and Mineral Research. 23:64-74

In postmenopausal women with a wide range of vertebral deformities, MRI-based structural measures of topology and scale at the distal radius are shown to account for as much as 30% of vertebral deformity, independent of integral vertebral BMD. Introd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fedfb08d2edfcdbdc5198c8245e9256
https://doi.org/10.1359/jbmr.070815

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