Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Michael J Trimble"'
Autor:
Daniel Pletzer, Evelyn Sun, Caleb Ritchie, Lauren Wilkinson, Leo T Liu, Michael J Trimble, Heidi Wolfmeier, Travis M Blimkie, Robert E W Hancock
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008444 (2020)
Cystic fibrosis (CF) is a genetic disease that affects mucin-producing body organs such as the lungs. Characteristic of CF is the production of thick, viscous mucus, containing the glycoprotein mucin, that can lead to progressive airway obstruction.
Externí odkaz:
https://doaj.org/article/d88ada66a6684776984907b7e6f26fb8
Autor:
Mauricio Gonçalves da Costa Sousa, Gabriela Conceição de Almeida, Danilo César Martins Mota, Rosiane Andrade da Costa, Simoni Campos Dias, Samuel Nunes Limberger, Frank Ko, Li Ting Lin, Evan F. Haney, Hashem Etayash, Beverlie Baquir, Michael J. Trimble, Ya Shen, Zheng Su, Markus Haapasalo, Daniel Pletzer, Letícia Chaves de Souza, Gláucia Schuindt Teixeira, Renato M. Silva, Robert E.W. Hancock, Octavio Luiz Franco, Taia Maria Berto Rezende
Publikováno v:
Bioactive Materials, Vol 16, Iss , Pp 173-186 (2022)
Multifunctional scaffolds with host defense peptides designed for regenerative endodontics are desirable nanobiotechnological tools for dentistry. Here, different scaffolds were tested for use during the pulp revascularization process, including poly
Externí odkaz:
https://doaj.org/article/383fc7caaba444be93bf353d6191ba66
Autor:
Bing (Catherine) Wu, Evan F. Haney, Noushin Akhoundsadegh, Daniel Pletzer, Michael J. Trimble, Alwin E. Adriaans, Peter H. Nibbering, Robert E. W. Hancock
Publikováno v:
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Bacterial biofilms cause 65% of all human infections and are highly resistant to antibiotic therapy but lack specific treatments. To provide a human organoid model for studying host-microbe interplay and enabling screening for novel antibiof
Externí odkaz:
https://doaj.org/article/6edc97ff207d4c43ab33703f19b764a3
Autor:
Antonio Facciuolo, Amy H. Lee, Michael J. Trimble, Neil Rawlyk, Hugh G. G. Townsend, Manjeet Bains, Natasa Arsic, Lucy M. Mutharia, Andrew Potter, Volker Gerdts, Scott Napper, Robert E. W. Hancock, Philip J. Griebel
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Mycobacterial diseases of cattle are responsible for considerable production losses worldwide. In addition to their importance in animals, these infections offer a nuanced approach to understanding persistent mycobacterial infection in native host sp
Externí odkaz:
https://doaj.org/article/e9742af5501a4eeb8a8910cde8d1390c
Publikováno v:
Biomolecules, Vol 8, Iss 2, p 29 (2018)
Biofilms are multicellular communities of bacteria that can adhere to virtually any surface. Bacterial biofilms are clinically relevant, as they are responsible for up to two-thirds of hospital acquired infections and contribute to chronic infections
Externí odkaz:
https://doaj.org/article/d85867efb13c4ff49cace8db74e50331
Autor:
Mauricio Gonçalves da Costa Sousa, Gabriela Conceição de Almeida, Danilo César Martins Mota, Rosiane Andrade da Costa, Simoni Campos Dias, Samuel Nunes Limberger, Frank Ko, Li Ting Lin, Evan F. Haney, Hashem Etayash, Beverlie Baquir, Michael J. Trimble, Ya Shen, Zheng Su, Markus Haapasalo, Daniel Pletzer, Letícia Chaves de Souza, Gláucia Schuindt Teixeira, Renato M. Silva, Robert E.W. Hancock, Octavio Luiz Franco, Taia Maria Berto Rezende
Publikováno v:
Bioactive materials. 16
Multifunctional scaffolds with host defense peptides designed for regenerative endodontics are desirable nanobiotechnological tools for dentistry. Here, different scaffolds were tested for use during the pulp revascularization process, including poly
Publikováno v:
Mol Microbiol
Motile bacteria are proficient at finding optimal environments for colonization. Often, they use chemotaxis to sense nutrient availability and dangerous concentrations of toxic chemicals. For many bacteria, the repertoire of chemoreceptors is large,
Autor:
Robert E. W. Hancock, Kathryn E. Fairfull-Smith, Christopher Barner-Kowollik, Leonie Barner, Vanessa Trouillet, Alexander Welle, Daniel Pletzer, Michael J. Trimble, Hendrik Woehlk, Sarah C. Mansour
Publikováno v:
Polymer Chemistry. 10:4252-4258
Bacterial biofilm formation on medical devices is a threat to healthcare systems worldwide as bacteria within a biofilm are more resistant to standard antimicrobial therapies. Herein, we introduce a nitroxide-based antibiofilm coating strategy, which
Autor:
Noushin Akhoundsadegh, Bing Catherine Wu, Evan F. Haney, Peter H. Nibbering, Daniel Pletzer, Michael J. Trimble, Robert E. W. Hancock, Alwin E Adriaans
Publikováno v:
NPJ Biofilms and Microbiomes
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-13 (2021)
npj Biofilms and Microbiomes, 7(1). NATURE RESEARCH
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-13 (2021)
npj Biofilms and Microbiomes, 7(1). NATURE RESEARCH
Bacterial biofilms cause 65% of all human infections and are highly resistant to antibiotic therapy but lack specific treatments. To provide a human organoid model for studying host-microbe interplay and enabling screening for novel antibiofilm agent
Publikováno v:
RSC advances. 11(5)
Health leaders and scientists worldwide consider antibiotic resistance among the world's most dangerous pathogens as one of the biggest threats to global health. Antibiotic resistance has largely been attributed to genetic changes, but the role and r