Zobrazeno 1 - 10
of 406
pro vyhledávání: '"Michael J Strong"'
Autor:
Aqila A Ahmed, Michael J Strong, Xiaofeng Zhou, Tyler Robinson, Sabrina Rocco, Geoffrey W Siegel, Gregory A Clines, Bethany B Moore, Evan T Keller, Nicholas J Szerlip
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0267642 (2022)
Roughly 400,000 people in the U.S. are living with bone metastases, the vast majority occurring in the spine. Metastases to the spine result in fractures, pain, paralysis, and significant health care costs. This predilection for cancer to metastasize
Externí odkaz:
https://doaj.org/article/a60036ad42f9468994f662df7dc31962
Autor:
Patrick McCunn, Kyle M Gilbert, Peter Zeman, Alex X Li, Michael J Strong, Ali R Khan, Robert Bartha
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215974 (2019)
PurposeNeurite Orientation Dispersion and Density Imaging (NODDI) is a diffusion MRI (dMRI) technique used to characterize tissue microstructure by compartmental modelling of neural water fractions. Intra-neurite, extra-neurite, and cerebral spinal f
Externí odkaz:
https://doaj.org/article/ed6fa124a6e64f038c2daa3aa0733100
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
The progressive degeneration of motor neurons in amyotrophic lateral sclerosis (ALS) is accompanied by the formation of a broad array of cytoplasmic and nuclear neuronal inclusions (protein aggregates) largely containing RNA-binding proteins such as
Externí odkaz:
https://doaj.org/article/f05e58e2e4c44623952c03fca6ab3b68
Autor:
Erin Santandrea, Farhang Aliakbari, Emily Truscott, Lynda McCaig, Neil S. Donison, Danielle Graham, Michael J. Strong, Kathryn Volkening
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-6 (2024)
Abstract Ethical animal use follows the 3R’s: Replacement, Reduction and Refinement. Here, we present the use of simultaneous jugular vein and cisterna magna catheterization via a port system in rats for repeated fluid sampling for 14 consecutive d
Externí odkaz:
https://doaj.org/article/3a60acbbf2c14d86bd7a9e0e73227a25
Autor:
Michael J Strong, Guorong Xu, Lisa Morici, Sandra Splinter Bon-Durant, Melody Baddoo, Zhen Lin, Claire Fewell, Christopher M Taylor, Erik K Flemington
Publikováno v:
PLoS Pathogens, Vol 10, Iss 11, p e1004437 (2014)
The high level of accuracy and sensitivity of next generation sequencing for quantifying genetic material across organismal boundaries gives it tremendous potential for pathogen discovery and diagnosis in human disease. Despite this promise, substant
Externí odkaz:
https://doaj.org/article/6e8712d11e804bbf8103a64d95686e14
Autor:
Guorong Xu, Michael J Strong, Michelle R Lacey, Carl Baribault, Erik K Flemington, Christopher M Taylor
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89445 (2014)
High-throughput RNA sequencing (RNA-seq) has become an instrumental assay for the analysis of multiple aspects of an organism's transcriptome. Further, the analysis of a biological specimen's associated microbiome can also be performed using RNA-seq
Externí odkaz:
https://doaj.org/article/69f58e50f5d34b6497cbf177ec720743
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85653 (2014)
Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by progressive motor neuron degeneration and neurofilament aggregate formation. Spinal motor neurons in ALS also show a selective suppression in the levels of low molecular weight n
Externí odkaz:
https://doaj.org/article/ad0918614c60496fa36f4253683dae1c
Autor:
Michael J Strong, Guorong Xu, Joseph Coco, Carl Baribault, Dass S Vinay, Michelle R Lacey, Amy L Strong, Teresa A Lehman, Michael B Seddon, Zhen Lin, Monica Concha, Melody Baddoo, Marybeth Ferris, Kenneth F Swan, Deborah E Sullivan, Matthew E Burow, Christopher M Taylor, Erik K Flemington
Publikováno v:
PLoS Pathogens, Vol 9, Iss 5, p e1003341 (2013)
Epstein-Barr virus (EBV) is associated with roughly 10% of gastric carcinomas worldwide (EBVaGC). Although previous investigations provide a strong link between EBV and gastric carcinomas, these studies were performed using selected EBV gene probes.
Externí odkaz:
https://doaj.org/article/77ca7fdd1bfd4c2d98126764863ee1ab
Autor:
Manuela Basso, Giuseppina Samengo, Giovanni Nardo, Tania Massignan, Giuseppina D'Alessandro, Silvia Tartari, Lavinia Cantoni, Marianna Marino, Cristina Cheroni, Silvia De Biasi, Maria Teresa Giordana, Michael J Strong, Alvaro G Estevez, Mario Salmona, Caterina Bendotti, Valentina Bonetto
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8130 (2009)
BACKGROUND:Amyotrophic lateral sclerosis (ALS) is a progressive and fatal motor neuron disease, and protein aggregation has been proposed as a possible pathogenetic mechanism. However, the aggregate protein constituents are poorly characterized so kn
Externí odkaz:
https://doaj.org/article/3c2c108b06e54b4694839cae0d95622e
Autor:
Joseph R. Linzey, Varun G. Kathawate, Michael J. Strong, Kayla Roche, Peyton E. Goethe, Lila R. Tudrick, Johan Lee, Arushi Tripathy, Sravanthi Koduri, Ayobami L. Ward, Oludotun Ogunsola, Mark M. Zaki, Rushikesh S. Joshi, Grant Weyburne, Charles S. Mayo, Joseph R. Evans, William C. Jackson, Nicholas J. Szerlip
Publikováno v:
Cancer Medicine, Vol 12, Iss 19, Pp 20177-20187 (2023)
Abstract Background As cancer therapies have improved, spinal metastases are increasingly common. Resulting complications have a significant impact on patient's quality of life. Optimal methods of surveillance and avoidance of neurologic deficits are
Externí odkaz:
https://doaj.org/article/2dc5d62a929943719618737080a66a75