Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Michael J Shelley"'
Autor:
Reza Farhadifar, Che-Hang Yu, Gunar Fabig, Hai-Yin Wu, David B Stein, Matthew Rockman, Thomas Müller-Reichert, Michael J Shelley, Daniel J Needleman
Publikováno v:
eLife, Vol 9 (2020)
The spindle shows remarkable diversity, and changes in an integrated fashion, as cells vary over evolution. Here, we provide a mechanistic explanation for variations in the first mitotic spindle in nematodes. We used a combination of quantitative gen
Externí odkaz:
https://doaj.org/article/eb04c23e32e04443a9ab2e61aafb1e5c
Publikováno v:
New Journal of Physics, Vol 23, Iss 1, p 013012 (2021)
Living matter moves, deforms, and organizes itself. In cells this is made possible by networks of polymer filaments and crosslinking molecules that connect filaments to each other and that act as motors to do mechanical work on the network. For the c
Externí odkaz:
https://doaj.org/article/edab17bb5a344f11991feb8ec098f433
Publikováno v:
eLife, Vol 4 (2015)
Many cellular processes are driven by cytoskeletal assemblies. It remains unclear how cytoskeletal filaments and motor proteins organize into cellular scale structures and how molecular properties of cytoskeletal components affect the large-scale beh
Externí odkaz:
https://doaj.org/article/1d3d11ca81674119af0f8ea6f08399f1
Autor:
Bryan Kaye, Olivia Stiehl, Peter J Foster, Michael J Shelley, Daniel J Needleman, Sebastian Fürthauer
Publikováno v:
New Journal of Physics, Vol 20, Iss 5, p 055012 (2018)
Spindles are self-organized microtubule-based structures that segregate chromosomes during cell division. The mass of the spindle is controlled by the balance between microtubule turnover and nucleation. The mechanisms that control the spatial regula
Externí odkaz:
https://doaj.org/article/ba68759a80fd4b57ae28d8f7a42545eb
Publikováno v:
New Journal of Physics, Vol 19, Iss 12, p 125011 (2017)
The cellular cytoskeleton is an active material, driven out of equilibrium by molecular motor proteins. It is not understood how the collective behaviors of cytoskeletal networks emerge from the properties of the network’s constituent motor protein
Externí odkaz:
https://doaj.org/article/7525c2be15464003bf2eb6ccf844dfef
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-7 (2022)
Rotor-like dynamics is observed in many natural systems, from the rotor proteins in cellular membranes to atmospheric models. Here, the authors uncover geometrical conservation laws that limit distribution of driven rotors in a membrane or a soap fil
Externí odkaz:
https://doaj.org/article/3535e763548147f3a9a7b3ec0327202b
Autor:
Nabila Founounou, Reza Farhadifar, Giovanna M. Collu, Ursula Weber, Michael J. Shelley, Marek Mlodzik
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Ommatidial rotation in the Drosophila eye is a regulated process and a Planar Cell Polarity (PCP) cell motility model. Here, the authors show that tissue fluidity via junctional remodeling, as regulated by the PCP effector kinase Nemo, is critical fo
Externí odkaz:
https://doaj.org/article/e2d76438c92f4084b28793c08567e39a
Publikováno v:
Mathematical Biosciences and Engineering, Vol 18, Iss 3, Pp 2849-2881 (2021)
Active fluids consume fuel at the microscopic scale, converting this energy into forces that can drive macroscopic motions over scales far larger than their microscopic constituents. In some cases, the mechanisms that give rise to this phenomenon hav
Externí odkaz:
https://doaj.org/article/0bc64f55899846948eda71572e358df6
Autor:
Saad Ansari, Wen Yan, Adam Ray Lamson, Michael J. Shelley, Matthew A. Glaser, Meredith D. Betterton
Publikováno v:
Frontiers in Physics, Vol 10 (2022)
Living systems exhibit self-organization, a phenomenon that enables organisms to perform functions essential for life. The interior of living cells is a crowded environment in which the self-assembly of cytoskeletal networks is spatially constrained
Externí odkaz:
https://doaj.org/article/88681f19fd0d4c27a4862ca56de067ca
Autor:
Sayantan Dutta, Reza Farhadifar, Wen Lu, Gokberk Kabacaoğlu, Robert Blackwell, David B. Stein, Margot Lakonishok, Vladimir I. Gelfand, Stanislav Y. Shvartsman, Michael J. Shelley
Life in complex systems, such as cities and organisms, comes to a standstill when global coordination of mass, energy, and information flows is disrupted. Global coordination is no less important in single cells, especially in large oocytes and newly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a57141f5707f5b5bdbce0a12457ec9f5
https://doi.org/10.1101/2023.04.04.534476
https://doi.org/10.1101/2023.04.04.534476