Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Michael J Roy"'
Autor:
Antony Morgan, Andrew Elders, Cam Donaldson, Julie Fox, Helen Mason, Michael P Kelly, Andrew Paterson, Sam Porter, Sarkis Manoukian, Rachel Mairi Baker, Mohasin Ahmed, Marcello Bertotti, John Cassidy, Rejoice Chipuriro, Emma Clewett, Lee Ann Fenge, Karen Galway, Aideen Gildea, Aileen McGuinness, Jennifer McLean, Jill Mulholland, Liam O'Hare, Jack Rendall, Michael J Roy, Peter Seaman, Merron Simpson, Artur Steiner
Publikováno v:
BMJ Open, Vol 13, Iss 3 (2023)
Introduction This research investigates how community-led organisations’ (CLOs’) use of assets-based approaches improves health and well-being, and how that might be different in different contexts. Assets-based approaches involve ‘doing with
Externí odkaz:
https://doaj.org/article/c9b6ab80c3394cf69986184934daf39e
Autor:
Chelsea Jones, Lorraine Smith-MacDonald, Matthew R G Brown, Jacob VanDehy, Rasmus Grunnet-Jepsen, Vrajeshri P Ordek, Sarah Kruger, Anne Ayres Gerhart, Nancy van Veelen, Mirjam J Nijdam, Lisa Burback, Bo Cao, Michael J Roy, Pinata Sessoms, Eric Vermetten, Suzette Brémault-Phillips
Publikováno v:
JMIR Human Factors, Vol 9, Iss 3, p e33682 (2022)
BackgroundIn recent years, the delivery of evidence-based therapies targeting posttraumatic stress disorder (PTSD) has been the focus of the Departments of Defense in countries such as Canada, the Netherlands, and the United States. More than 66% of
Externí odkaz:
https://doaj.org/article/0b352a8cbe8843dfa9520226cc441c8a
Autor:
Krista Beth Highland, Michelle eCostanzo, Tanja eJovanovic, Seth D. Norrholm, Rochelle B. Ndiongue, Brian J. Reinhardt, Barbara eRothbaum, Albert A. Rizzo, Michael J Roy
Publikováno v:
Frontiers in Psychology, Vol 6 (2015)
PTSD symptoms can result in functional impairment among service members (SMs), even in those without a clinical diagnosis. The variability in outcomes may be related to underlying catecholamine mechanisms. Individuals with PTSD tend to have elevated
Externí odkaz:
https://doaj.org/article/5b065f1689c34ed889608c82797e9456
Autor:
Steven J Durning, Michelle eCostanzo, Anthony R Artino, Liselotte N Dyrbye, Thomas J Beckman, Lambert eSchuwirth, Eric eHolmboe, Michael J Roy, Christopher M Wittich, Rebecca S Lipner, Cees evan der Vleuten
Publikováno v:
Frontiers in Psychiatry, Vol 4 (2013)
Burnout is prevalent in residency training and practice and is linked to medical error and suboptimal patient care. However, little is known about how burnout affects clinical reasoning, which is essential to safe and effective care. The aim of this
Externí odkaz:
https://doaj.org/article/6275568c699f45ef88f924edc7d3111a
Autor:
Michael J. Roy, David O. Keyser, Sheilah S. Rowe, Rene S. Hernandez, Marcia Dovel, Holland Romero, Diana Lee, Matthew Menezes, Elizabeth Magee, Danielle J. Brooks, Chen Lai, Jessica Gill, Suthee Wiri, Elizabeth Metzger, J. Kent Werner, Douglas Brungart, Devon M. Kulinski, Dominic Nathan, Walter S. Carr
Publikováno v:
BMC Medical Research Methodology, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Subconcussive blast exposure during military training has been the subject of both anecdotal concerns and reports in the medical literature, but prior studies have often been small and have used inconsistent methods. Methods This
Externí odkaz:
https://doaj.org/article/ee8b95f0db7a4a8dbccac3089422f894
Autor:
Christiane Kofink, Nicole Trainor, Barbara Mair, Simon Wöhrle, Melanie Wurm, Nikolai Mischerikow, Michael J. Roy, Gerd Bader, Peter Greb, Géraldine Garavel, Emelyne Diers, Ross McLennan, Claire Whitworth, Vesna Vetma, Klaus Rumpel, Maximilian Scharnweber, Julian E. Fuchs, Thomas Gerstberger, Yunhai Cui, Gabriela Gremel, Paolo Chetta, Stefan Hopf, Nicole Budano, Joerg Rinnenthal, Gerhard Gmaschitz, Moriz Mayer, Manfred Koegl, Alessio Ciulli, Harald Weinstabl, William Farnaby
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Protein degraders are an emerging drug modality; however, their properties lie beyond typical drug-like space. Here the authors report optimisation via structure-based exit vector and linker design towards the VHL-recruiting PROTAC ACBI2, an orally b
Externí odkaz:
https://doaj.org/article/3f90550853c6402d8f154d10f8e2a18c
Autor:
JoAnn Difede, Barbara O. Rothbaum, Albert A. Rizzo, Katarzyna Wyka, Lisa Spielman, Christopher Reist, Michael J. Roy, Tanja Jovanovic, Seth D. Norrholm, Judith Cukor, Megan Olden, Charles E. Glatt, Francis S. Lee
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Posttraumatic stress disorder (PTSD) is a significant public health issue. Yet, there are limited treatment options and no data to suggest which treatment will work for whom. We tested the efficacy of virtual reality exposure (VRE) or prolon
Externí odkaz:
https://doaj.org/article/5e8a0e3e727e4599a276f2a89f1693e4
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Patel et al. report crystal structures of the kinase domain of Doublecortin-like kinase 1 (DCLK1) in complex with a potent inhibitor and its precursors. Their structural study reveals insights into the mode of action of the inhibitor DCLK1-IN-1 and s
Externí odkaz:
https://doaj.org/article/6b6a664c847645569a2bc4e72fd9c9cb
Autor:
Michael J. Roy, Paula Bellini, Sarah E. Kruger, Kerri Dunbar, Hannah Atallah, Thaddeus Haight, Eric Vermetten
Publikováno v:
Frontiers in Virtual Reality, Vol 3 (2022)
Background and Purpose: PTSD and mTBI are persistent and frequently comorbid after combat, yet current therapies often achieve only modest impact. A novel exposure-based “walk and talk” cognitive therapy, Motion-Assisted, Multi-Modal Memory Desen
Externí odkaz:
https://doaj.org/article/8695aef25d1f4863bb1a98220249937d
Autor:
Dilorom Sass, Vivian A. Guedes, Ethan G. Smith, Rany Vorn, Christina Devoto, Katie A. Edwards, Sara Mithani, James Hentig, Chen Lai, Chelsea Wagner, Kerri Dunbar, David R. Hyde, Leorey Saligan, Michael J. Roy, Jessica Gill
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Traumatic brain injury (TBI) affects millions of Americans each year and has been shown to disproportionately impact those subject to greater disparities in health. Female sex is one factor that has been associated with disparities in health outcomes
Externí odkaz:
https://doaj.org/article/c50d86c8996749688f062fe7a4ef47b7