Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Michael J Plevin"'
Autor:
Daniel E Foxler, Katherine S Bridge, John G Foster, Paul Grevitt, Sean Curry, Kunal M Shah, Kathryn M Davidson, Ai Nagano, Emanuela Gadaleta, Hefin I Rhys, Paul T Kennedy, Miguel A Hermida, Ting‐Yu Chang, Peter E Shaw, Louise E Reynolds, Tristan R McKay, Hsei‐Wei Wang, Paulo S Ribeiro, Michael J Plevin, Dimitris Lagos, Nicholas R Lemoine, Prabhakar Rajan, Trevor A Graham, Claude Chelala, Kairbaan M Hodivala‐Dilke, Ian Spendlove, Tyson V Sharp
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 8, Pp 1-18 (2018)
Abstract The adaptive cellular response to low oxygen tensions is mediated by the hypoxia‐inducible factors (HIFs), a family of heterodimeric transcription factors composed of HIF‐α and HIF‐β subunits. Prolonged HIF expression is a key contri
Externí odkaz:
https://doaj.org/article/9b04680e29334b599d9575042b42aeeb
Publikováno v:
Biochemical Society Transactions. 50:1555-1567
The study of protein structure, dynamics and function by NMR spectroscopy commonly requires samples that have been enriched (‘labelled') with the stable isotopes 13C and/or 15N. The standard approach is to uniformly label a protein with one or both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5220827a0470ed44a36484d576913b9
https://doi.org/10.1042/bst20210586
https://doi.org/10.1042/bst20210586
Autor:
Katherine S. Bridge, Kunal M. Shah, Yigen Li, Daniel E. Foxler, Sybil C.K. Wong, Duncan C. Miller, Kathryn M. Davidson, John G. Foster, Ruth Rose, Michael R. Hodgkinson, Paulo S. Ribeiro, A. Aziz Aboobaker, Kenta Yashiro, Xiaozhong Wang, Paul R. Graves, Michael J. Plevin, Dimitris Lagos, Tyson V. Sharp
Publikováno v:
Cell Reports, Vol 20, Iss 1, Pp 173-187 (2017)
As core components of the microRNA-induced silencing complex (miRISC), Argonaute (AGO) proteins interact with TNRC6 proteins, recruiting other effectors of translational repression/mRNA destabilization. Here, we show that LIMD1 coordinates the assemb
Externí odkaz:
https://doaj.org/article/dd86764956e7461fbbd192078a7216b7
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 8 (2021)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 8 (2021)
A large number of eukaryotic proteins are processed by single or combinatorial post-translational covalent modifications that may alter their activity, interactions and fate. The set of modifications of each protein may be considered a “regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff5586550965a3fe7be6e7e43f413f5
https://eprints.whiterose.ac.uk/175619/1/fmolb_08_692668.pdf
https://eprints.whiterose.ac.uk/175619/1/fmolb_08_692668.pdf
Autor:
James W. B. Moir, Emanuele Paci, S.C. Griffiths, Huw T. Jenkins, Jennifer R. Potts, Alexander N. St John, Christoph G. Baumann, Aleix Lafita, James Alexander Hinett Gilburt, Clement Degut, Fiona Whelan, Michael J. Plevin, Alex Bateman
Changes at the cell surface enable bacteria to survive in dynamic environments, such as diverse niches of the human host. Here, we reveal “Periscope Proteins” as a widespread mechanism of bacterial surface alteration mediated through protein leng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f88f30ba202f14c837a0057192de86de
https://doi.org/10.1101/2020.12.24.424174
https://doi.org/10.1101/2020.12.24.424174
Autor:
Ewan Parry, Adam Dowle, Tony R. Larson, Pegine B. Walrad, Angela K. Cruz, Tiago R. Ferreira, Michael J. Plevin, Karen Hogg, Foteini Kolokousi, Eliza V. C. Alves-Ferreira
Publikováno v:
Nucleic Acids Research
RNA binding proteins (RBPs) are the primary gene regulators in kinetoplastids as transcriptional control is nearly absent, making Leishmania an exceptional model for investigating methylation of non-histone substrates. Arginine methylation is an evol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f919c07f531766204d67656e73c91d2b
https://pubmed.ncbi.nlm.nih.gov/32365184
https://pubmed.ncbi.nlm.nih.gov/32365184
Autor:
A. Aziz Aboobaker, Paul R. Graves, Kunal Shah, Duncan Miller, Dimitris Lagos, Xiaozhong Wang, Michael R. Hodgkinson, Kathryn M. Davidson, Katherine S. Bridge, Yigen Li, Tyson V. Sharp, Kenta Yashiro, Sybil C.K. Wong, Paulo S. Ribeiro, Michael J. Plevin, John G. Foster, Ruth Sarah Rose, Daniel E. Foxler
Publikováno v:
Cell Reports
Cell Reports, Vol 20, Iss 1, Pp 173-187 (2017)
Cell Reports, Vol 20, Iss 1, Pp 173-187 (2017)
Summary As core components of the microRNA-induced silencing complex (miRISC), Argonaute (AGO) proteins interact with TNRC6 proteins, recruiting other effectors of translational repression/mRNA destabilization. Here, we show that LIMD1 coordinates th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46d797594c0d8570ff6839e422e42e8
http://europepmc.org/articles/PMC5507773
http://europepmc.org/articles/PMC5507773
Autor:
R.J. Spears, James A. Brannigan, Martin A. Fascione, A. Marek Brzozowski, Tessa Keenan, Sophie McKenna, Robin Brabham, Darshita Budhadev, Julia Walton, Michael J. Plevin, Anthony J. Wilkinson
The bioconjugation of proteins with small molecules has proved an invaluable strategy for probing and perturbing dynamic biological mechanisms. The general use of chemical methods for the functionalisation of proteins remains limited however by the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f812031f09948e80a10316a61e59c408
Publikováno v:
Current Opinion in Structural Biology
Current Opinion in Structural Biology, Elsevier, 2015, 32, pp.113-122. ⟨10.1016/j.sbi.2015.03.009⟩
Current Opinion in Structural Biology, 2015, 32, pp.113-122. ⟨10.1016/j.sbi.2015.03.009⟩
Current Opinion in Structural Biology, Elsevier, 2015, 32, pp.113-122. ⟨10.1016/j.sbi.2015.03.009⟩
Current Opinion in Structural Biology, 2015, 32, pp.113-122. ⟨10.1016/j.sbi.2015.03.009⟩
International audience; Nuclear magnetic resonance (NMR) spectroscopy is a uniquely powerful tool for studying the structure, dynamics and interactions of biomolecules at atomic resolution. In the past 15 years, the development of new isotopic labeli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a4c2bad0dc6179fdc8bc29f40a8daf
https://doi.org/10.1016/j.sbi.2015.03.009
https://doi.org/10.1016/j.sbi.2015.03.009
Publikováno v:
Wiley Interdisciplinary Reviews: RNA. 6:271-289
HIV TAR RNA-binding protein (TRBP) and Protein Activator of PKR (PACT) are double-stranded (ds) RNA-binding proteins that participate in both small regulatory RNA biogenesis and the response to viral dsRNA. Despite considerable progress toward unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9c8142889fdf12bb1279ea5b1ea281d
https://doi.org/10.1002/wrna.1272
https://doi.org/10.1002/wrna.1272