Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Michael J Passineau"'
Autor:
Danielle Wu, Isabelle M. A. Lombaert, Maximilien DeLeon, Swati Pradhan-Bhatt, Robert L Witt, Daniel Anton Harrington, Mark G Trombetta, Michael J Passineau, Mary C. Farach-Carson
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
An urgent need exists to develop large animal models for preclinical testing of new cell therapies designed to replace lost or damaged tissues. Patients receiving irradiation for treatment of head and neck cancers frequently develop xerostomia/dry mo
Externí odkaz:
https://doaj.org/article/b1a7b1ea291e4850b4d36bb97d29470c
Autor:
Ramaz Geguchadze, Zhimin Wang, Lee Zourelias, Paola Perez-Riveros, Paul C Edwards, Laurie Machen, Michael J Passineau
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
In this study, we compared gene transfer efficiency and host response to ultrasound-assisted, nonviral gene transfer with a conventional plasmid and a minicircle vector in the submandibular salivary glands of mice. Initially, we looked at gene transf
Externí odkaz:
https://doaj.org/article/c9e59ba853c0417e86452f58fa2def47
Autor:
Anton V Borovjagin, Juan Dong, Michael J Passineau, Changchun Ren, Ejvis Lamani, Olga A Mamaeva, Hongju Wu, Enid Keyser, Miho Murakami, Shuo Chen, Mary MacDougall
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e24281 (2011)
To explore gene therapy strategies for amelogenesis imperfecta (AI), a human ameloblast-like cell population was established from third molars of an AI-affected patient. These cells were characterized by expression of cytokeratin 14, major enamel pro
Externí odkaz:
https://doaj.org/article/3b833be8d48b4150b0e6af1695327761
Autor:
Isabelle M.A. Lombaert, Vaishali N. Patel, Christina E. Jones, Derrick C. Villier, Ashley E. Canada, Matthew R. Moore, Elsa Berenstein, Changyu Zheng, Corinne M. Goldsmith, John A. Chorini, Daniel Martin, Lee Zourelias, Mark G. Trombetta, Paul C. Edwards, Kathleen Meyer, Dale Ando, Michael J. Passineau, Matthew P. Hoffman
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 839-855 (2020)
Salivary gland hypofunction causes significant morbidity and loss of quality of life for head and neck cancer patients treated with radiotherapy. Preventing hypofunction is an unmet therapeutic need. We used an adeno-associated virus serotype 2 (AAV2
Externí odkaz:
https://doaj.org/article/9043b0d9998246adb36e026172057354
Autor:
Dong Hun Lee, Sarah S. Chang, Minseong Kim, Raham Lee, Andrew J. Jang, Juyoung Kim, Jing Ma, Michael J. Passineau, Raymond L. Benza, Harry Karmouty-Quintana, Wilbur A. Lam, Roy L. Sutliff, C. Michael Hart, Changwon Park, Bum-Yong Kang
Endothelial-to-mesenchymal transition (EndoMT) plays an important role in pulmonary hypertension (PH). Also, the molecular mechanisms regulating EndoMT in PH remain to be defined. In this study, we first showed that reduced expression of the transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca686d31b02ce814867bc409fcfb6411
https://doi.org/10.21203/rs.3.rs-2380412/v1
https://doi.org/10.21203/rs.3.rs-2380412/v1
Autor:
Choon-Myung Lee, Roy L. Sutliff, Jing Ma, Raymond L. Benza, Andrew J. Jang, Sarah S. Chang, Michael J. Passineau, Changwon Park, C. Michael Hart, Bum-Yong Kang, David R. Archer
Publikováno v:
Blood Adv
Sickle cell disease (SCD)-associated pulmonary hypertension (PH) causes significant morbidity and mortality. Here, we defined the role of endothelial specific peroxisome proliferator-activated receptor γ (PPARγ) function and novel PPARγ/HUWE1/miR-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7a258b8b77db798b276d14159cf76e
https://doi.org/10.1182/bloodadvances.2020002754
https://doi.org/10.1182/bloodadvances.2020002754
Autor:
Dong Hun Lee, Minseong Kim, Sarah S. Chang, Andrew J. Jang, Juyoung Kim, Jing Ma, Michael J. Passineau, Raymond L. Benza, Harry Karmouty-Quintana, Wilbur A. Lam, Roy L. Sutliff, C. Michael Hart, Changwon Park, Bum-Yong Kang
Endothelial-to-mesenchymal transition (EndoMT) plays an important role in pulmonary hypertension (PH). Also, the molecular mechanisms regulating EndoMT in PH remain to be defined. In this study, we first showed that reduced expression of the transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dc708b53b824fecb9f589969a9c3084
https://doi.org/10.1101/2022.05.17.492293
https://doi.org/10.1101/2022.05.17.492293
Autor:
Andrew J. Jang, Victor Tseng, Jae Sun Kim, Robert S. Stearman, Yutong Zhao, Jing Zhao, Jiwoong Choi, John Lister, Michael J. Passineau, Wilbur A. Lam, Changwon Park, Raymond J. Benza, Bum-Yong Kang
IntroductionPulmonary arterial hypertension (PAH) is a progressive, lethal, and incurable disease of the pulmonary vasculature. Evolving evidence indicates that the ubiquitin-specific proteases (USPs), play an important role in the pathogenesis of PA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::509b50e89e1334248e4af113850c264b
https://doi.org/10.1101/2022.05.17.492159
https://doi.org/10.1101/2022.05.17.492159
Autor:
Michael S. Halbreiner, Michael J. Passineau, Aman Ladak, Deepika Dixit, Cameron N. Riviere, Srinivas Murali
Publikováno v:
Robotic Surgery: Research and Reviews
Aman Ladak,1 Deepika Dixit,1 Michael S Halbreiner,2 Michael J Passineau,2 Srinivas Murali,2 Cameron N Riviere1 1The Robotics Institute, Carnegie Mellon University, Pittsburgh, PA, USA; 2Cardiovascular Institute, Allegheny Health Network, Pittsburgh,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3203fc797be53f449caf72637a34f7a
https://www.dovepress.com/introducer-design-concepts-for-an-epicardial-parallel-wire-robot-peer-reviewed-fulltext-article-RSRR
https://www.dovepress.com/introducer-design-concepts-for-an-epicardial-parallel-wire-robot-peer-reviewed-fulltext-article-RSRR
Autor:
Eric C. Shiao, Michael S. Halbreiner, Srinivas Murali, Michael J. Passineau, Cameron N. Riviere, Eric T. Rasmussen, Lee Zourelias
Publikováno v:
Int J Med Robot
BACKGROUND: HeartLander is a tethered robot walker that utilizes suction to adhere to the beating heart. HeartLander can be used for minimally invasive administration of cardiac medications or ablation of tissue. In order to administer injections saf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c1348ec28cf37dae348e3c1cb14471
https://europepmc.org/articles/PMC8416707/
https://europepmc.org/articles/PMC8416707/