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pro vyhledávání: '"Michael J Newbold"'
Autor:
Michael J Newbold, Anurag Paul, Jun-Lin Guan, Megan E Bischoff, Jarek Meller, Nicholas J Talbot, Adam D Price, Yuanwei Zang, Maria F. Czyzyk-Krzeska, Birgit Ehmer, Johnson Chu, David R. Plas
Publikováno v:
The Journal of Cell Biology
The work identifies a noncanonical autophagic program mediated by the hominid-specific LC3C paralog functioning downstream from the von Hippel–Lindau tumor suppressor. The program targets for lysosomal degradation postdivision midbodies in a mechan
Autor:
Megan E. Bischoff, Yuanwei Zang, Johnson Chou, Adam D. Price, Birgit Ehmer, Nicholas J. Talbot, Michael J. Newbold, Anurag Paul, Jun-Lin Guan, David R. Plas, Jarek Meller, Maria F. Czyzyk-Krzeska
LC3s are canonical proteins necessary for the formation of autophagosomes. We have previously established that two paralogs, LC3B and LC3C, have opposite activities in renal cancer, with LC3B playing oncogenic role and LC3C tumor suppressing role. LC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f3b96edef35831b2e84293daab1795e
https://doi.org/10.1101/2021.02.19.431861
https://doi.org/10.1101/2021.02.19.431861