Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Michael J Meehan"'
Autor:
Samantha J Mascuch, Wilna J Moree, Cheng-Chih Hsu, Gregory G Turner, Tina L Cheng, David S Blehert, A Marm Kilpatrick, Winifred F Frick, Michael J Meehan, Pieter C Dorrestein, Lena Gerwick
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119668 (2015)
White-nose syndrome (WNS) caused by the pathogenic fungus Pseudogymnoascus destructans is decimating the populations of several hibernating North American bat species. Little is known about the molecular interplay between pathogen and host in this di
Externí odkaz:
https://doaj.org/article/98305b9b6f1e4535b2dc586698fd1609
Autor:
Wout Bittremieux, Nicole E. Avalon, Sydney P. Thomas, Sarvar A. Kakhkhorov, Alexander A. Aksenov, Paulo Wender P. Gomes, Christine M. Aceves, Andrés Mauricio Caraballo-Rodríguez, Julia M. Gauglitz, William H. Gerwick, Tao Huan, Alan K. Jarmusch, Rima F. Kaddurah-Daouk, Kyo Bin Kang, Hyun Woo Kim, Todor Kondić, Helena Mannochio-Russo, Michael J. Meehan, Alexey V. Melnik, Louis-Felix Nothias, Claire O’Donovan, Morgan Panitchpakdi, Daniel Petras, Robin Schmid, Emma L. Schymanski, Justin J. J. van der Hooft, Kelly C. Weldon, Heejung Yang, Shipei Xing, Jasmine Zemlin, Mingxun Wang, Pieter C. Dorrestein
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Despite the increasing availability of tandem mass spectrometry (MS/MS) community spectral libraries for untargeted metabolomics over the past decade, the majority of acquired MS/MS spectra remain uninterpreted. To further aid in interpretin
Externí odkaz:
https://doaj.org/article/1eb1ab39bd1848068d742dc4af2edb11
Autor:
Julia M. Gauglitz, Kiana A. West, Wout Bittremieux, Candace L. Williams, Kelly C. Weldon, Morgan Panitchpakdi, Francesca Di Ottavio, Christine M. Aceves, Elizabeth Brown, Nicole C. Sikora, Alan K. Jarmusch, Cameron Martino, Anupriya Tripathi, Michael J. Meehan, Kathleen Dorrestein, Justin P. Shaffer, Roxana Coras, Fernando Vargas, Lindsay DeRight Goldasich, Tara Schwartz, MacKenzie Bryant, Gregory Humphrey, Abigail J. Johnson, Katharina Spengler, Pedro Belda-Ferre, Edgar Diaz, Daniel McDonald, Qiyun Zhu, Emmanuel O. Elijah, Mingxun Wang, Clarisse Marotz, Kate E. Sprecher, Daniela Vargas-Robles, Dana Withrow, Gail Ackermann, Lourdes Herrera, Barry J. Bradford, Lucas Maciel Mauriz Marques, Juliano Geraldo Amaral, Rodrigo Moreira Silva, Flavio Protasio Veras, Thiago Mattar Cunha, Rene Donizeti Ribeiro Oliveira, Paulo Louzada-Junior, Robert H. Mills, Paulina K. Piotrowski, Stephanie L. Servetas, Sandra M. Da Silva, Christina M. Jones, Nancy J. Lin, Katrice A. Lippa, Scott A. Jackson, Rima Kaddurah Daouk, Douglas Galasko, Parambir S. Dulai, Tatyana I. Kalashnikova, Curt Wittenberg, Robert Terkeltaub, Megan M. Doty, Jae H. Kim, Kyung E. Rhee, Julia Beauchamp-Walters, Kenneth P. Wright, Maria Gloria Dominguez-Bello, Mark Manary, Michelli F. Oliveira, Brigid S. Boland, Norberto Peporine Lopes, Monica Guma, Austin D. Swafford, Rachel J. Dutton, Rob Knight, Pieter C. Dorrestein
Publikováno v:
Nature biotechnology, vol 40, iss 12
Nat Biotechnol
Nat Biotechnol
Human untargeted metabolomics studies annotate only ~10% of molecular features. We introduce reference-data-driven analysis to match metabolomics tandem mass spectrometry (MS/MS) data against metadata-annotated source data as a pseudo-MS/MS reference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fadcc5a8ebaed4c919d942163887bc61
https://doi.org/10.1038/s41587-022-01368-1
https://doi.org/10.1038/s41587-022-01368-1
Autor:
Anupriya Tripathi, Zhenjiang Zech Xu, Jin Xue, Orit Poulsen, Antonio Gonzalez, Gregory Humphrey, Michael J. Meehan, Alexey V. Melnik, Gail Ackermann, Dan Zhou, Atul Malhotra, Gabriel G. Haddad, Pieter C. Dorrestein, Rob Knight
Publikováno v:
mSystems, Vol 4, Iss 2 (2019)
ABSTRACT Studying perturbations in the gut ecosystem using animal models of disease continues to provide valuable insights into the role of the microbiome in various pathological conditions. However, understanding whether these changes are consistent
Externí odkaz:
https://doaj.org/article/360e9ad0df024316b20c5bcfd26a7877
Autor:
Anupriya Tripathi, Alexey V. Melnik, Jin Xue, Orit Poulsen, Michael J. Meehan, Gregory Humphrey, Lingjing Jiang, Gail Ackermann, Daniel McDonald, Dan Zhou, Rob Knight, Pieter C. Dorrestein, Gabriel G. Haddad
Publikováno v:
mSystems, Vol 3, Iss 3 (2018)
ABSTRACT Obstructive sleep apnea (OSA) is a common disorder characterized by episodic obstruction to breathing due to upper airway collapse during sleep. Because of the episodic airway obstruction, intermittently low O2 (hypoxia) and high CO2 (hyperc
Externí odkaz:
https://doaj.org/article/c01326f5b4b0417ba6d9d3532c83605c
Autor:
Leigh-Ana Rossitto, Robert H. Mills, Rebecca Daly, Vivian Hook, Dilip V. Jeste, Toer W. Stevens, Anaamika Campeau, David Gonzalez, Pieter C. Dorrestein, Michael J. Meehan, Tanya T. Nguyen
Publikováno v:
Molecular Psychiatry. 27:1217-1225
Schizophrenia is a devastating psychiatric illness that detrimentally affects a significant portion of the worldwide population. Aging of schizophrenia patients is associated with reduced longevity, but the potential biological factors associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09ae6d11b960fd6ec3caa26f95a3023f
https://doi.org/10.1038/s41380-021-01339-z
https://doi.org/10.1038/s41380-021-01339-z
Autor:
Jiao Song, Xuejun Liu, Tadimeti S. Rao, Leon Chang, Michael J. Meehan, Jonathan M. Blevitt, Jiejun Wu, Pieter C. Dorrestein, Marcos E. Milla
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 8, Pp 1492-1500 (2015)
It is widely accepted that small-molecule drugs, despite their selectivity at primary targets, exert pharmacological effects (and safety liabilities) through a multiplicity of pathways. As such, it has proved extremely difficult to experimentally ass
Externí odkaz:
https://doaj.org/article/9989f770ca9941abb958d69de43d9575
Autor:
Wout Bittremieux, Nicole E. Avalon, Sydney P. Thomas, Sarvar A. Kakhkhorov, Alexander A. Aksenov, Paulo Wender P. Gomes, Christine M. Aceves, Andrés Mauricio Caraballo Rodríguez, Julia M. Gauglitz, William H. Gerwick, Alan K. Jarmusch, Rima F. Kaddurah-Daouk, Kyo Bin Kang, Hyun Woo Kim, Todor Kondić, Helena Mannochio-Russo, Michael J. Meehan, Alexey V. Melnik, Louis-Felix Nothias, Claire O’Donovan, Morgan Panitchpakdi, Daniel Petras, Robin Schmid, Emma L. Schymanski, Justin J. J. van der Hooft, Kelly C. Weldon, Heejung Yang, Jasmine Zemlin, Mingxun Wang, Pieter C. Dorrestein
Despite the increasing availability of tandem mass spectrometry (MS/MS) community spectral libraries for untargeted metabolomics over the past decade, the majority of acquired MS/MS spectra remain uninterpreted. To further aid in interpreting unannot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b11898a0338fd5901f67974b5e7fee1
https://doi.org/10.1101/2022.05.15.490691
https://doi.org/10.1101/2022.05.15.490691
Autor:
Rodrigo Moreira da Silva, Tara Schwartz, Juliano Geraldo Amaral, Thiago M. Cunha, Scott Jackson, MacKenzie Bryant, Francesca Diottavio, Robert H. Mills, Norberto Peporine Lopes, Robert Terkeltaub, Katrice Lippa, Brigid S. Boland, Christina Jones, Pieter C. Dorrestein, Morgan Panitchpakdi, Mingxun Wang, Megan M. Doty, Christine M. Aceves, Candace L. Williams, Fernando Vargas, Monica Guma, Michael J. Meehan, Lucas Miranda Marques, Renê Donizeti Ribeiro de Oliveira, Rachel J. Dutton, Stephanie Servetas, Nancy Lin, Qiyun Zhu, Paulo Louzada-Junior, Jae H. Kim, Edgar Diaz, Douglas Galasko, Austin D. Swafford, Maria Gloria Dominguez-Bello, Nicole Sikora, Paulina Piotrowski, Wout Bittremieux, Abigail J. Johnson, Cameron Martino, Clarisse Marotz, Rob Knight, Lourdes Herrera, Michelli F. Oliveira, Kate E. Sprecher, Rima Kaddurah Daouk, Elijah Emmanuel, Dana Withrow, Tatyana Kalashnikova, Curt Wittenberg, Kiana West, Pedro Belda-Ferre, Alan K. Jarmusch, Daniela Vargas Robles, Mark Manery, Barry J. Bradford, Kathleen Dorrestein, Flávio Protaso Veras, Kenneth P. Wright, Gail Ackermann, Greg Humphrey, Daniel McDonald, Lindsay DeRight Goldasich, Anupriya Tripathi, Sandra DaSilva, Julia Gauglitz, David Gonzalez, Roxana Coras, Elizabeth Brown, Kyung E. Rhee, Katharina Spengler, Parambir S. Dulai, Julia Beauchamp-Walters, Kelly C. Weldon, Justin P. Shaffer
Human untargeted metabolomics studies succeed in annotating only ~10% of molecular features. We, therefore, introduce reference data-driven analysis that uses the source data as a pseudo-MS/MS reference library to match against human metabolomics MS/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9f8b9788cae579d9220939f069d2709
https://doi.org/10.21203/rs.3.rs-654519/v1
https://doi.org/10.21203/rs.3.rs-654519/v1
Autor:
Hannah Tsunemoto, Nicholas Dillon, Anne Lamsa, Adam M. Feist, Victor Nizet, Jonathan M. Monk, Joseph Sugie, Saugat Poudel, Rob Knight, Yara Seif, Joe Pogliano, Alison Vrbanac, Richard Szubin, Connor A. Olson, Pieter C. Dorrestein, Bernhard O. Palsson, Akanksha Rajput, Samira Dahesh, Michael J. Meehan
Publikováno v:
GigaScience, vol 10, iss 1
Rajput, A, Poudel, S, Tsunemoto, H, Meehan, M, Szubin, R, Olson, C A, Seif, Y, Lamsa, A, Dillon, N, Vrbanac, A, Sugie, J, Dahesh, S, Monk, J M, Dorrestein, P C, Knight, R, Pogliano, J, Nizet, V, Feist, A M & Palsson, B O 2021, ' Identifying the effect of vancomycin on health care-associated methicillin-resistant Staphylococcus aureus strains using bacteriological and physiological media ', GigaScience, vol. 10, no. 1, giaa156 . https://doi.org/10.1093/gigascience/giaa156
GigaScience
Rajput, A, Poudel, S, Tsunemoto, H, Meehan, M, Szubin, R, Olson, C A, Seif, Y, Lamsa, A, Dillon, N, Vrbanac, A, Sugie, J, Dahesh, S, Monk, J M, Dorrestein, P C, Knight, R, Pogliano, J, Nizet, V, Feist, A M & Palsson, B O 2021, ' Identifying the effect of vancomycin on health care-associated methicillin-resistant Staphylococcus aureus strains using bacteriological and physiological media ', GigaScience, vol. 10, no. 1, giaa156 . https://doi.org/10.1093/gigascience/giaa156
GigaScience
Background The evolving antibiotic-resistant behavior of health care–associated methicillin-resistant Staphylococcus aureus (HA-MRSA) USA100 strains are of major concern. They are resistant to a broad class of antibiotics such as macrolides, aminog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c17f7d88df6c641c22fb10d22940b67e
https://escholarship.org/uc/item/7fm6w9gt
https://escholarship.org/uc/item/7fm6w9gt