Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Michael J Massare"'
Autor:
Qingqing Xie, Zhao Wang, Fengyun Ni, Xiaorui Chen, Jianpeng Ma, Nita Patel, Hanxin Lu, Ye Liu, Jing-Hui Tian, David Flyer, Michael J Massare, Larry Ellingsworth, Gregory Glenn, Gale Smith, Qinghua Wang
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0210749 (2019)
Globally, human respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections in newborns, young children, and the elderly for which there is no vaccine. The RSV fusion (F) glycoprotein is a major target for vaccine devel
Externí odkaz:
https://doaj.org/article/cfdeb2d3629d4702a3334786e4caba93
Autor:
James Logue, Robert M. Johnson, Nita Patel, Bin Zhou, Sonia Maciejewski, Bryant Foreman, Haixia Zhou, Alyse D. Portnoff, Jing-Hui Tian, Asma Rehman, Marisa E. McGrath, Robert E. Haupt, Stuart M. Weston, Lauren Baracco, Holly Hammond, Mimi Guebre-Xabier, Carly Dillen, M. Madhangi, Ann M. Greene, Michael J. Massare, Greg M. Glenn, Gale Smith, Matthew B. Frieman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Current SARS-CoV-2 variants evade immune responses induced by approved vaccines. In this study, the authors find that a recombinant prefusion-stabilized Beta spike protein vaccine confers broad neutralization capacity in mice and non-human primates a
Externí odkaz:
https://doaj.org/article/6b9ab71cb4bd4f84b8cc8463a5dfad83
Autor:
Joyce S. Plested, Mingzhu Zhu, Shane Cloney-Clark, Edmond Massuda, Urvashi Patel, Andrew Klindworth, Michael J. Massare, Rongman Cai, Louis Fries, Greg Glenn, Raj Kalkeri
Publikováno v:
Microorganisms, Vol 11, Iss 2, p 368 (2023)
Emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) show immune evasion of vaccine-derived immunity, highlighting the need for better clinical immunogenicity biomarkers. To address this need, an enzyme-linked immunosorbe
Externí odkaz:
https://doaj.org/article/eccebede663c4ad0a28cb35070d10ef6
Autor:
Nita Patel, Jing-Hui Tian, Rhonda Flores, Kelsey Jacobson, Michelle Walker, Alyse Portnoff, Mimi Gueber-Xabier, Michael J. Massare, Greg Glenn, Larry Ellingsworth, Gale Smith
Publikováno v:
Vaccines, Vol 8, Iss 4, p 607 (2020)
Human respiratory syncytial virus (RSV) is a cause of lower respiratory tract infection in infants, young children, and older adults. There is no licensed vaccine and prophylactic treatment options are limited. The RSV fusion (F) glycoprotein is a ta
Externí odkaz:
https://doaj.org/article/598d642f569b456488cf6ec1898051de
Autor:
Alyse D. Portnoff, Nita Patel, Michael J. Massare, Haixia Zhou, Jing-Hui Tian, Bin Zhou, Vivek Shinde, Gregory M. Glenn, Gale Smith
Publikováno v:
Vaccines, Vol 8, Iss 1, p 99 (2020)
Influenza vaccine effectiveness varies annually due to the fast evolving seasonal influenza A(H3N2) strain and egg-derived mutations—both of which can cause a mismatch between the vaccine and circulating strains. To address these limitations, we ha
Externí odkaz:
https://doaj.org/article/ecfaff4913b34e2888ceb5da44359788
Autor:
Nita Patel, Carolin Loos, Ann M. Greene, Douglas A. Lauffenburger, Erica Ollmann Saphire, Fatima Amanat, Ricardo Carrion, Alyse D. Portnoff, Sonia Maciejewski, Florian Krammer, Gale Smith, Caroline Atyeo, Krista M. Pullen, Matthew B. Frieman, Yenny Goez-Gazi, Dansu Yuan, Michael J. Massare, Bin Zhou, Matthew J. Gorman, David C. Montefiori, Marisa McGrath, Colin Mann, Kathryn Bowman, Jing-Hui Tian, Galit Alter, Alex Lee Zhu, Gregory M. Glenn, Mimi Guebre-Xabier, Sharon L. Schendel, Larry Ellingsworth, James Logue
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 9, Pp 100405-(2021)
Cell Reports Medicine
Cell Reports Medicine
Recently approved vaccines have shown remarkable efficacy in limiting SARS-CoV-2 associated disease. However, with the variety of vaccines, immunization strategies, and waning antibody titers, defining correlates of immunity across a spectrum of anti
Autor:
Galit Alter, Carolin Loos, Ann M. Greene, Colin Mann, Alex Lee Zhu, James Logue, Kathryn Bowman, Jing-Hui Tian, Sonia Maciejewski, Larry Ellingsworth, Matthew B. Frieman, Sharon L. Schendel, Marisa McGrath, Ricardo Carrion, Gregory M. Glenn, Alyse D. Portnoff, Michael J. Massare, Matthew J. Gorman, Florian Krammer, Bin Zhou, Dansu Yuan, E.O. Saphire, David C. Montefiori, Gale Smith, Douglas A. Lauffenburger, Fatima Amanat, Yenny Goez-Gazi, Mimi Guebre-Xabier, Caroline Atyeo, Nita Patel, Krista M. Pullen
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Recently approved vaccines have already shown remarkable protection in limiting SARS-CoV-2 associated disease. However, immunologic mechanism(s) of protection, as well as how boosting alters immunity to wildtype and newly emerging strains, remain inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c0a0da458a71a51787ac51bca4fa7a
https://doi.org/10.1101/2021.02.05.429759
https://doi.org/10.1101/2021.02.05.429759
Autor:
Carolin Loos, Gregory M. Glenn, Nita Patel, Ricardo Carrion, Kathryn Bowman, Michael J. Massare, Florian Krammer, Mimi Guebre-Xabier, Caroline Atyeo, Krista M. Pullen, Matthew B. Frieman, Larry Ellingsworth, Bin Zhou, Ann M. Greene, Douglas A. Lauffenburger, Dansu Yaun, Fatima Amanat, David C. Montefiori, Marisa McGrath, Jing-Hui Tian, Gale Smith, Yenny Goez-Gazi, Alex Lee Zhu, Alyse D. Portnoff, James Logue, Sonia Maciejewski, Sharon L. Schendel, Colin Mann, Erica Ollmann Saphire, Matthew J. Gorman, Galit Alter
Publikováno v:
Research Square
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Recently approved vaccines have shown remarkable protection in limiting SARS-CoV-2 associated disease. However, immunologic mechanism(s) of protection, and how boosting alters immunity to wildtype and newly emerging strains, remains incompletely unde
Autor:
Sonia Maciejewski, Louis Fries, Gale Smith, Holly L. Hammond, Robert Haupt, Alyse D. Portnoff, Nita Patel, C. Jason Wong, Kelsey Jacobson, Betty Ekechukwu, James Logue, James Norton, Bin Zhou, James F. Papin, Sarathi Boddapati, Matthew B. Frieman, Mimi Guebre-Xabier, Malgorzata Wisniewska, Stefanie Kluepfel-Stahl, Michael J. Massare, Stuart Weston, Will Moffitt, Haixia Zhou, Pedro A. Piedra, Gregory M. Glenn, Karin Lövgren Bengtsson, Jing Hui Tian, Larry Ellingsworth, Rafia Khatoon, Linda Stertman
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The COVID-19 pandemic continues to spread throughout the world with an urgent need for a safe and protective vaccine to effectuate herd protection and control the spread of SARS-CoV-2. Here, we report the development of a SARS-CoV-2 subunit vaccine (
NVX-CoV2373 vaccine protects cynomolgus macaque upper and lower airways against SARS-CoV-2 challenge
Autor:
Pedro A. Piedra, Sonia Maciejewski, Kristal Lam, Matthew B. Frieman, Gale Smith, Jing-Hui Tian, Mimi Guebre-Xabier, Bin Zhou, Gregory M. Glenn, Nita Patel, Alyse D. Portnoff, Michael J. Massare, Larry Ellingsworth
Publikováno v:
Vaccine
Highlights • Full-length SARS-CoV-2 prefusion spike with Matrix-M™ (NVX-CoV2373) vaccine. • Induced hACE2 receptor blocking and neutralizing antibodies in macaques. • Vaccine protected against SARS-CoV-2 replication in the nose and lungs. •
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee8d32055e3178457a3ed467d0515f3
https://doi.org/10.1101/2020.08.18.256578
https://doi.org/10.1101/2020.08.18.256578