Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Michael J Mant"'
Autor:
Hemalatha Kuppusamy, Helga M Ogmundsdottir, Eva Baigorri, Amanda Warkentin, Hlif Steingrimsdottir, Vilhelmina Haraldsdottir, Michael J Mant, John Mackey, James B Johnston, Sophia Adamia, Andrew R Belch, Linda M Pilarski
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100691 (2014)
Genetic variations in the hyaluronan synthase 1 gene (HAS1) influence HAS1 aberrant splicing. HAS1 is aberrantly spliced in malignant cells from multiple myeloma (MM) and Waldenstrom macroglobulinemia (WM), but not in their counterparts from healthy
Externí odkaz:
https://doaj.org/article/3b3843e51fba436ebe244549f552ce0a
Autor:
Loree Larratt, Elena Liew, Nancy Zhu, Joseph Brandwein, Sunita Ghosh, Lauren Bolster, Anthea Peters, Robert Turner, Lalit Saini, Jeffery M. Patterson, Marlene Hamilton, Bruce Ritchie, Cynthia Wu, Irwindeep Sandhu, Michael J. Mant
Publikováno v:
European journal of haematology. 97(5)
We conducted a retrospective study assessing FLAG (fludarabine, cytarabine, and granulocyte colony-stimulating factor) as first-line treatment in 56 newly diagnosed acute myeloid leukemia patients considered ineligible for anthracycline-based treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ca8c8b82f274ef1ec63e793e586f2a
https://pubmed.ncbi.nlm.nih.gov/27028202
https://pubmed.ncbi.nlm.nih.gov/27028202
Autor:
Minakshi Taparia, Irwindeep Sandhu, Graeme R. Quest, Lalit Saini, Robert Turner, Elena Liew, Imran Mirza, Bruce Ritchie, Cynthia Wu, Loree Larratt, Sunita Ghosh, Michael J. Mant, Marlene Hamilton, Susan Nahirniak, Lauren Bolster, Jeffery M. Patterson, Nancy Zhu, Anthea Peters, Joseph Brandwein
Publikováno v:
Leukemia research. 45
Most guidelines suggest that only the bone marrow aspirate (BMA) is necessary to assess residual disease following intensive chemotherapy for Acute Myeloid Leukemia (AML) with the bone marrow trephine biopsy (BMTB) recommended in cases of a poor qual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962c7d5333145e1c79e20324a2039e5f
https://pubmed.ncbi.nlm.nih.gov/27092851
https://pubmed.ncbi.nlm.nih.gov/27092851
Autor:
Jitra Kriangkum, Michael J. Mant, Andrew Belch, Linda M. Pilarski, Brian J. Taylor, Tony Reiman, Julie A. Pittman
Publikováno v:
Blood. 112:1894-1903
Multiple myeloma (MM) is a cancer of plasma cells (PCs) expressing immunoglobulin heavy chain (IgH) postswitch isotypes. The discovery of earlier stage cells related to postswitch PCs, called preswitch clonotypic IgM (cIgM) cells led to the hypothesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b47a384db7be593cb0c3b281447368
https://doi.org/10.1182/blood-2008-01-129221
https://doi.org/10.1182/blood-2008-01-129221
Publikováno v:
Acta Orthopaedica. 79:794-799
Deep vein thrombosis (DVT), usually asymptomatic, is common after total hip arthroplasty (THA). Post-thrombotic syndrome (PTS) is a potential late complication of DVT, but there is limited data on its occurrence.This was a prospective cohort study of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd0c1ef9090635b2eca3fa71f47c859
https://doi.org/10.1080/17453670810016876
https://doi.org/10.1080/17453670810016876
Autor:
Jitra Kriangkum, Brian J. Taylor, Steven P. Treon, Michael J. Mant, Andrew R. Belch, Tony Reiman, Linda M. Pilarski
Publikováno v:
Clinical Cancer Research. 13:2005-2013
Purpose: Malignant B lineage cells in Waldenstrom's macroglobulinemia (WM) express a unique clonotypic IgM VDJ. The occurrence of biclonal B cells and their clonal relationships were characterized.Experimental Design: Bone marrow and blood from 20 WM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bcc9b93ac455d059e6127f724c0036
https://doi.org/10.1158/1078-0432.ccr-06-2788
https://doi.org/10.1158/1078-0432.ccr-06-2788
Publikováno v:
Clinical Gastroenterology and Hepatology. 4:451-454
Background & Aims: By using colorimetric tests, reports have indicated that occult gastrointestinal bleeding is common in celiac disease. These results suggest that bleeding is a significant contributor to iron deficiency in this disorder and imply a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd62acea800a7d84f8b30fe1ca7f5e4b
https://doi.org/10.1016/j.cgh.2005.12.010
https://doi.org/10.1016/j.cgh.2005.12.010
Autor:
Tony Reiman, Jitra Kriangkum, Linda M. Pilarski, Brian J. Taylor, Michael J. Mant, Andrew R. Belch, Erin Strachan
Publikováno v:
Blood. 107:2920-2927
Analysis of clonotypic isotype class switching (CSR) in Waldenström macroglobulinemia (WM) and IgM monoclonal gammopathy of undetermined significance (MGUS) reveals a normal initial phase of B-cell activation as determined by constitutive and induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20e9e231428e662b7be10bf22b26b44
https://doi.org/10.1182/blood-2005-09-3613
https://doi.org/10.1182/blood-2005-09-3613
Autor:
Sophia Adamia, Mary Crainie, Andrew R. Belch, Linda M. Pilarski, Tony Reiman, Michael J. Mant
Publikováno v:
Blood. 105:4836-4844
In this study, we show that the hyaluronan synthase 1 (HAS1) gene undergoes aberrant intronic splicing in multiple myeloma (MM). In addition to HAS1 full length (HAS1FL), we identify 3 novel splice variants of HAS1, HAS1Va, HAS1Vb, and HAS1Vc, detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528ed28035e9d2c314b3ce6f3a7a6e32
https://doi.org/10.1182/blood-2004-10-3825
https://doi.org/10.1182/blood-2004-10-3825
Autor:
Olivier Tournilhac, Tony Reiman, Linda M. Pilarski, Steven P. Treon, Michael J. Mant, Sophia Adamia, Andrew Belch, Carrie McQuarrie
Publikováno v:
Clinical Lymphoma. 5:253-256
The hyaluronan synthase 1 (HAS1) gene encodes a plasma membrane protein that synthesizes hyaluronan, an extracellular matrix molecule. Previously, in patients with Waldenstrom's macroglobulinemia (WM), we detected upregulation of HAS1 transcripts and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa3c8da61e522191c292a44ca612d933
https://doi.org/10.3816/clm.2005.n.010
https://doi.org/10.3816/clm.2005.n.010