Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Michael J Mallory"'
Autor:
Matthew G Thompson, Mark Dittmar, Michael J Mallory, Prasanna Bhat, Max B Ferretti, Beatriz MA Fontoura, Sara Cherry, Kristen W Lynch
Publikováno v:
eLife, Vol 9 (2020)
Viral infection induces the expression of numerous host genes that impact the outcome of infection. Here, we show that infection of human lung epithelial cells with influenza A virus (IAV) also induces a broad program of alternative splicing of host
Externí odkaz:
https://doaj.org/article/a84b06f84ac540deb0cf5b99ca91f58a
Autor:
Sarah A Smith, Debashish Ray, Kate B Cook, Michael J Mallory, Timothy R Hughes, Kristen W Lynch
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80701 (2013)
HnRNP (heterogeneous nuclear ribonucleoprotein) proteins are a large family of RNA-binding proteins that regulate numerous aspects of RNA processing. Interestingly, several paralogous pairs of hnRNPs exist that exhibit similar RNA-binding specificity
Externí odkaz:
https://doaj.org/article/666ae6998adb40649666e7000e53def5
Autor:
Laura M. Agosto, Michael J. Mallory, Max B. Ferretti, Davia Blake, Keegan S. Krick, Matthew R. Gazzara, Benjamin A. Garcia, Kristen W. Lynch
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112273- (2023)
Summary: Chromatin regulation and alternative splicing are both critical mechanisms guiding gene expression. Studies have demonstrated that histone modifications can influence alternative splicing decisions, but less is known about how alternative sp
Externí odkaz:
https://doaj.org/article/07b7255a22c54daf86da08fcb975ee19
Autor:
Matthew R. Gazzara, Rakesh Chatrikhi, Robert Jordan Ontiveros, Michael J. Mallory, Kristen W. Lynch, Sean P. McClory
Publikováno v:
Nucleic Acids Research
RNA binding proteins (RBPs) frequently regulate the expression of other RBPs in mammalian cells. Such cross-regulation has been proposed to be important to control networks of coordinated gene expression; however, much remains to be understood about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe54859fe030b812485e97e6a2b00e31
http://europepmc.org/articles/PMC7261192
http://europepmc.org/articles/PMC7261192
Autor:
Yoseph Barash, Rakesh Chatrikhi, David C. Schultz, Michael J. Mallory, Kristen W. Lynch, Martin Carroll, Osvaldo D. Rivera, Sara Cherry, Mathieu Quesnel-Vallières
Publikováno v:
Proc Natl Acad Sci U S A
Most genes associated with acute myeloid leukemia (AML) are mutated in less than 10% of patients, suggesting that alternative mechanisms of gene disruption contribute to this disease. Here, we find a set of splicing events that alter the expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296e4207b3bd8ea7703b36f3d91f61b9
https://pubmed.ncbi.nlm.nih.gov/33876749
https://pubmed.ncbi.nlm.nih.gov/33876749
Autor:
Michael J. Mallory, Max Ferretti, Mark Dittmar, Kristen W. Lynch, Matthew G. Thompson, Prasanna Bhat, Beatriz M. A. Fontoura, Sara Cherry
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Viral infection induces the expression of numerous host genes that impact the outcome of infection. Here we show that infection of human lung epithelial cells with Influenza A virus (IAV) also induces a broad program of alternative splicing of host g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7625f979e1ef3c552d35130fb1bb8ac
https://doi.org/10.7554/elife.55500
https://doi.org/10.7554/elife.55500
Autor:
Mark Dittmar, Sara Cherry, Beatriz M. A. Fontoura, Michael J. Mallory, Max Ferretti, Kristen W. Lynch, Matthew G. Thompson, Prasanna Bhat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd67881981878f4d1b7195cba2defc91
https://doi.org/10.7554/elife.55500.sa2
https://doi.org/10.7554/elife.55500.sa2
Autor:
Yoseph Barash, Martin Carroll, Sara Cherry, Mathieu Quesnel-Vallières, Michael J. Mallory, David C. Schultz, Kristen W. Lynch, Osvaldo D. Rivera
Most genes associated with Acute Myeloid Leukemia (AML) are mutated in less than 10% of patients, suggesting alternative mechanisms for gene disruption contribute to this disease. Here we find a set of splicing events that disrupt the expression of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::216d4b5a785069cd0d3d6685036697cb
https://doi.org/10.1101/2020.05.21.107557
https://doi.org/10.1101/2020.05.21.107557
Autor:
Jinsong Qiu, Iulia Tapescu, Xiang-Dong Fu, Michael J. Mallory, Brian S. Cole, Kristen W. Lynch, Samuel J. Allon, Hua-Ying Fan, Robert J. Lake
Publikováno v:
RNA. 21:2053-2066
HnRNP L is a ubiquitous splicing-regulatory protein that is critical for the development and function of mammalian T cells. Previous work has identified a few targets of hnRNP L-dependent alternative splicing in T cells and has described transcriptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc165ce00312b46f6dd00c6210774277
https://doi.org/10.1261/rna.052969.115
https://doi.org/10.1261/rna.052969.115
Autor:
Xiang-Dong Fu, Michael J. Mallory, Iulia Tapescu, Christopher A. Yarosh, Kristen W. Lynch, Matthew G. Thompson, Jinsong Qiu
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 43, iss 18
Nucleic acids research, vol 43, iss 18
PSF (a.k.a. SFPQ) is a ubiquitously expressed, essential nuclear protein with important roles in DNA damage repair and RNA biogenesis. In stimulated T cells, PSF binds to and suppresses the inclusion of CD45 exon 4 in the final mRNA; however, in rest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e526376f22a34c9d525a01539d59a6
http://europepmc.org/articles/PMC4605305
http://europepmc.org/articles/PMC4605305