Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Michael J Hansbury"'
Autor:
Aidan G. Gilmartin, James D. Winkler, Michael J Hansbury, A. Colombo, Jeffrey R. Jackson, Paola Zaratin, Boyd B Scott, C. Belpasso
Publikováno v:
Biochemical and Biophysical Research Communications. 328:409-414
Angiopoietin-1 (Ang-1) is one of a family of ligands for the Tie-2 receptor which has been demonstrated to be involved in angiogenesis. Little is known about the regulation of Ang-1 gene expression. We have previously demonstrated that TNF-alpha is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba6b8c395faf307093bd167c9e52e33
https://doi.org/10.1016/j.bbrc.2004.12.180
https://doi.org/10.1016/j.bbrc.2004.12.180
Autor:
Beverly A Tinkelenberg, Sal Caradonna, Michael J Hansbury, Robert D. Ladner, Imane Elateri, Susan Muller-Weeks
Publikováno v:
DNA Repair. 2:315-323
There are at least four distinct families of enzymes that recognize and remove uracil from DNA. Family-3 (SMUG1) enzymes have recently been identified and have a preference for uracil in single-stranded DNA when assayed in vitro. Here we investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e82129dded03fa4037cb5d6d2ec4051
https://doi.org/10.1016/s1568-7864(02)00221-5
https://doi.org/10.1016/s1568-7864(02)00221-5
Publikováno v:
Angiogenesis. 4:29-36
The Tie2 receptor and its known ligands, the angiopoietins, play a critical role in endothelial cell differentiation during the process of angiogenesis. Recent experimental observations indicate that the agonistic ligand, angiopoietin-1, can stimulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe456d3d0cbec95d9ca8d75e0b7c8524
https://doi.org/10.1023/a:1016678828930
https://doi.org/10.1023/a:1016678828930
Autor:
Lisa A. Marshall, Michael J. Hansbury, Brian J. Bolognese, Rebecca J. Gum, Peter R. Young, Ruth J. Mayer
Publikováno v:
The Journal of Immunology. 161:6005-6013
CD23, the low affinity IgE receptor, is up-regulated on the surface of IL-4-treated B cells and monocytes and is immediately proteolytically processed, releasing soluble fragments of CD23. Here, we report that inhibitors of the p38 mitogen-activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20ad8842a693db444317ffd3cd018808
https://doi.org/10.4049/jimmunol.161.11.6005
https://doi.org/10.4049/jimmunol.161.11.6005
Autor:
Kevin Moulder, Lisa Marshall, Gregory P. Harper, Ruth J. Mayer, Michael J. Hansbury, Vivienne M. Spackman, Gary Christie, Brian Bolognese, Derek R. Buckle, Sheila M. Seal, Aisling Barton, Mark McCord, Richard M. Cook, Paul R. Murdock, Beverley Jane Weston
Publikováno v:
European Journal of Immunology. 27:3228-3235
CD23, the low-affinity IgE receptor, is up-regulated on interleukin (IL)-4-stimulated B cells and monocytes, with a concomitant increase in the release of soluble fragments of CD23 (sCD23) into the medium by proteolytic processing of the surface-boun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd02c239fef7410a3eaebd99098144ef
https://doi.org/10.1002/eji.1830271221
https://doi.org/10.1002/eji.1830271221
Autor:
Susan J. Muller, Mary C. Kosciuk, Robert D. Ladner, Frank Lynch, Sal Caradonna, Michael J Hansbury
Publikováno v:
Experimental Cell Research. 222:345-359
Evidence is presented on two forms of uracil-DNA glycosylase (UDG1 and UDG2) that exist in human cells. We have developed an affinity technique to isolate uracil-DNA glycosylases from HeLa cells. This technique relies on the use of a uracil-DNA glyco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e84815435b60352a097feb69ab8e17
https://doi.org/10.1006/excr.1996.0044
https://doi.org/10.1006/excr.1996.0044
Publikováno v:
Biochemical and Biophysical Research Communications. 171:525-530
Molecular analysis of the induction of the lutropin/choriogonadotropin receptor during the process of luteinization of the rat ovary was performed. The appearance of receptor binding activity and an immunological analysis of the receptor using Triton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509cfd4e900118718e920aa2fb76f60e
https://doi.org/10.1016/0006-291x(90)91177-t
https://doi.org/10.1016/0006-291x(90)91177-t
Autor:
Scott K. Thompson, Randall K. Johnson, Thau F. Ho, Keith W. Ward, Lara S. Kallander, Thaddeus A. Tomaszek, Cheryl A. Janson, Kyung O. Johanson, Robert B. Kirkpatrick, Ward W. Smith, Guang Yang, Michael R. Mattern, Gui-Feng Zhang, Christina K. Schulz-Pritchard, Michael J Hansbury, Ryan M Dominic, Wenfang Chen, James D. Winkler, Thomas D. Meek, Daniel F. Veber, David G. Tew, Qing Lu, P.W. Fisher, Glenn A. Hofmann
Publikováno v:
Journal of medicinal chemistry. 48(18)
Inhibitors of human methionine aminopeptidase type 2 (hMetAP2) are of interest as potential treatments for cancer. A new class of small molecule reversible inhibitors of hMetAP2 was discovered and optimized, the 4-aryl-1,2,3-triazoles. Compound 24, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1be748eb5e7ee3f51352eb14a0c3d0
https://pubmed.ncbi.nlm.nih.gov/16134930
https://pubmed.ncbi.nlm.nih.gov/16134930
Publikováno v:
Cancer research. 62(17)
The thymidylate synthase reaction remains an important target for widely used anticancer agents; however, the clinical utility of these drugs is limited by the occurrence of cellular resistance. Despite the considerable amount of information availabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::361a869da611f541df678d9229e8c322
https://pubmed.ncbi.nlm.nih.gov/12208740
https://pubmed.ncbi.nlm.nih.gov/12208740
Autor:
Boyd B, Scott, Paola F, Zaratin, Antonio, Colombo, Michael J, Hansbury, James D, Winkler, Jeffrey R, Jackson
Publikováno v:
The Journal of rheumatology. 29(2)
Angiopoietin- I (Ang-1) and Ang-2 are ligands for the receptor tyrosine kinase, Tie-2. Ang-1, a Tie-2 agonist, may have a vascular stabilizing role in angiogenesis, while Ang-2, an endogenous antagonist of Tie-2, may have an early role in angiogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d64a10e38ff147b39ed61155cad5155
https://pubmed.ncbi.nlm.nih.gov/11838839
https://pubmed.ncbi.nlm.nih.gov/11838839