Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michael J Gerst"'
Autor:
Karen B. Young, Evangelia G. Kranias, Michael J Gerst, James Gulick, Jeffrey Robbins, Qiujing Song, Guoxiang Chu, Ingrid L. Grupp
Publikováno v:
The FASEB Journal. 18:974-976
The relative amount of sarcoplasmic reticulum Ca2+-ATPase (SERCA2a) and its crucial inhibitor phospholamban (PLN) are closely regulated and play a pivotal role in maintaining muscle function. The functional importance of PLN has been intensively inve
Autor:
Vivek J. Kadambi, Rajesh Dash, Evangelia G. Kranias, Anand Pathak, Danuta Biniakiewicz, Michael J Gerst, Albrecht Schmidt, Brian D. Hoit, William T. Abraham
Publikováno v:
Cardiovascular research. 57(3)
Objective: Exogenous catecholamine exposure has been associated with p38 mitogen-activated protein kinase (MAPK) and cardiac hypertrophy. In this study, we investigated the regulation of p38 MAPK in cardiac remodeling elicited by endogenous adrenergi
Autor:
Evangelia G. Kranias, Muthu Periasamy, Michael J Gerst, Yong Ji, Albrecht Schmidt, Konrad Frank, Wen Zhao, Guoxiang Chu
Publikováno v:
Cardiovascular research. 57(1)
Objective: Phospholamban ablation or ectopic expression of SERCA1a in the heart results in significant increases in cardiac contractile parameters. The aim of the present study was to determine whether a combination of these two genetic manipulations
Autor:
Helen Kiriazis, Yoji Sato, Evangelia G. Kranias, Brian D. Hoit, Albrecht Schmidt, Michael J Gerst, Vivek J. Kadambi
Publikováno v:
Cardiovascular research. 53(2)
Objective: To determine whether the hyperdynamic phospholamban-knockout hearts are capable of withstanding a chronic aortic stenosis. Methods: The transverse section of the aorta was banded in phospholamban-knockout and their isogenic wild-type mice,
Autor:
Danuta Biniakiewicz, Michael J. Gerst, Stephen B. Liggett, Gerald W. Dorn, Vivek J. Kadambi, Rajesh Dash, Evangelia G. Kranias, John N. Lorenz, William T. Abraham, Nicole M. Tepe, Brian D. Hoit, Amy M. Canning, Albrecht Schmidt
Publikováno v:
Circulation. 103(6)
Background —Relieving the inhibition of sarcoplasmic reticular function by phospholamban is a major target of β-adrenergic stimulation. Chronic β-adrenergic receptor activity has been suggested to be detrimental, on the basis of transgenic overex
Autor:
Qiujing Song, Jeffrey Robbinst, Ingrid L. Grupp, Evangelia G. Kranias, Karen B. Young, Guoxiang Chu, Michael J Gerst
Publikováno v:
Journal of Molecular and Cellular Cardiology. 33:A135