Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Michael J Gale"'
Autor:
Amy E L Stone, Angela Mitchell, Jessica Brownell, Daniel J Miklin, Lucy Golden-Mason, Stephen J Polyak, Michael J Gale, Hugo R Rosen
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e95627 (2014)
Plasmacytoid Dendritic Cells (pDCs) represent a key immune cell population in the defense against viruses. pDCs detect viral pathogen associated molecular patterns (PAMPs) through pattern recognition receptors (PRR). PRR/PAMP interactions trigger sig
Externí odkaz:
https://doaj.org/article/60497fd4ff8e4c45bce47e4059ad1892
Autor:
Michael J. Gale, Hope E. Titus, Gareth A. Harman, Talal Alabduljalil, Anna Dennis, Jenny L. Wilson, David M. Koeller, Erika Finanger, Peter A. Blasco, Pei-Wen Chiang, Daniel J. Karr, Paul Yang
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 10, Iss , Pp 244-248 (2018)
Purpose: We present the first detailed ophthalmic description of a child with Helsmoortel-Van der Aa Syndrome (HVDAS), including longitudinal follow-up and analysis. Observations: After extensive workup, a young child with poor visual behavior, hypot
Externí odkaz:
https://doaj.org/article/5509eb93e5144c8faea09c0a6efe526d
Autor:
Kellyn N. Bellsmith, Michael J. Gale, Sen Yang, Isabelle B. Nguyen, Christa J. Prentiss, Luan T. Nguyen, Sam Mershon, Allison I. Summers, Merina Thomas
Publikováno v:
JAMA ophthalmology. 140(5)
Visual acuity (VA) is one of the most important clinical data points in ophthalmology. However, few options for validated at-home VA assessments are currently available.To validate 3 at-home visual acuity tests in comparison with in-office visual acu
Autor:
Paul K. Drain, Ronit R. Dalmat, Linhui Hao, Meagan J. Bemer, Elvira Budiawan, Jennifer F. Morton, Renee C. Ireton, Tien-Ying Hsiang, Zarna Marfatia, Roshni Prabhu, Claire Woosley, Adanech Gichamo, Elena Rechkina, Daphne Hamilton, Michalina Montaño, Jason L. Cantera, Alexey S. Ball, Inah Golez, Elise Smith, Alexander L. Greninger, M. Juliana McElrath, Matthew Thompson, Benjamin D. Grant, Allison Meisner, Geoffrey S. Gottlieb, Michael J. Gale
Publikováno v:
Journal of Clinical Virology. 161:105420
BackgroundGuidelines for SARS-CoV-2 have relied on limited data on duration of viral infectiousness and correlation with COVID-19 symptoms and diagnostic testing.MethodsWe enrolled ambulatory adults with acute SARS-CoV-2 infection and performed seria
Publikováno v:
The Journal of Immunology. 204:68.3-68.3
RIG-I-like receptors (RLRs) are DEAD-box helicases and cytoplasmic pathogen recognition receptors that recognize and bind to nonself/viral RNA and trigger innate antiviral immunity. RLRs are essential for the detection of RNA virus infection and incl
Publikováno v:
The Journal of Immunology. 200:115.8-115.8
The NLRP3 protein is a key initiator of inflammation in humans. NLRP3 becomes activated by a multitude of danger signals, including pathogens, markers of metabolic dysfunction, and internalized particulates. Upon activation, NLRP3 nucleates formation
Publikováno v:
Advances in experimental medicine and biology. 854
The purpose of this study was to correlate features on flood-illuminated adaptive optics (AO) images with color fundus, fundus autofluorescence (FAF) and spectral domain optical coherence tomography (SD-OCT) images in patients with retinitis pigmento
Publikováno v:
The Journal of Immunology. 198:148.13-148.13
RIG-I-Like Receptors (RLRs) include RIG-I, MDA5, and LGP2. RLRs are vital pathogen recognition receptors in the defense against RNA viruses. West Nile Virus (WNV) is an emerging, neurotropic flavivirus that infects the central nervous system to cause
Autor:
Jessica B Graham, Jessica Swarts, Sunil Thomas, Courtney Wilkins, Martin Ferris, Michael J Gale, Jennifer M Lund
Publikováno v:
The Journal of Immunology. 196:79.11-79.11
West Nile Virus (WNV) is a cytopathic neurotropic flavivirus that causes a wide range of infection states in humans, ranging from asymptomatic to severe neuroinvasive disease. This variation supports the idea that host genetics play an important role
Autor:
Daniela Giordano, Kevin E Draves, Marianne A Bryan, Christiane Dresch, Lucy B Young, Kelsey Roe, Justin M Richner, Michael S Diamond, Michael J Gale, Edward A Clark
Publikováno v:
The Journal of Immunology. 196:146.13-146.13
BAFFR−/− mice are a model of humoral immunodeficiency since they lack mature B cells. We found that in contrast to WT mice BAFFR−/− mice were highly susceptible to WNV. BAFFR−/− mice infected with 100pfu WNV succumbed to infection between