Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Michael J Dagley"'
Autor:
Jiyoti Verma-Gaur, Yue Qu, Paul F Harrison, Tricia L Lo, Tara Quenault, Michael J Dagley, Matthew Bellousoff, David R Powell, Traude H Beilharz, Ana Traven
Publikováno v:
PLoS Genetics, Vol 11, Iss 10, p e1005590 (2015)
The yeast Candida albicans is a human commensal and opportunistic pathogen. Although both commensalism and pathogenesis depend on metabolic adaptation, the regulatory pathways that mediate metabolic processes in C. albicans are incompletely defined.
Externí odkaz:
https://doaj.org/article/26d369bd1bb9478b876a665e3593e08e
Publikováno v:
PLoS Pathogens, Vol 11, Iss 2, p e1004683 (2015)
Information on the growth rate and metabolism of microbial pathogens that cause long-term chronic infections is limited, reflecting the absence of suitable tools for measuring these parameters in vivo. Here, we have measured the replication and physi
Externí odkaz:
https://doaj.org/article/ac267e0f616f4038bcbfe85880fcc2ec
Autor:
Pavel Dolezal, Michael J Dagley, Maya Kono, Peter Wolynec, Vladimir A Likić, Jung Hock Foo, Miroslava Sedinová, Jan Tachezy, Anna Bachmann, Iris Bruchhaus, Trevor Lithgow
Publikováno v:
PLoS Pathogens, Vol 6, Iss 3, p e1000812 (2010)
Several essential biochemical processes are situated in mitochondria. The metabolic transformation of mitochondria in distinct lineages of eukaryotes created proteomes ranging from thousands of proteins to what appear to be a much simpler scenario. I
Externí odkaz:
https://doaj.org/article/953953f7b9624adf836cb8eaec47afad
Autor:
Erica Wynne-Jones, Kylie M. Quinn, Lisa M Assmus, Kim L. Good-Jacobson, Laura K. Mackay, Carolien E. van de Sandt, Georg Ramm, Wai K Lam, Tabinda Hussain, Michael J Dagley, Nicole L. La Gruta, Liyen Loh, Malcolm J. McConville, Katherine Kedzierska, Michael T. Ryan, Lucy Cooper, Felix Kraus, Luke E. Formosa, Eleanor C Saunders
Publikováno v:
Nature communications, 11(1):2857. Nature Publishing Group
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Virtual memory T (TVM) cells are antigen-naïve CD8+ T cells that exist in a semi-differentiated state and exhibit marked proliferative dysfunction in advanced age. High spare respiratory capacity (SRC) has been proposed as a defining metabolic chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b9d439a40478ff5044380707195fc4
https://doi.org/10.1038/s41467-020-16633-7
https://doi.org/10.1038/s41467-020-16633-7
Autor:
Michael J Dagley, Erica Wynne-Jones, Laura K. Mackay, Felix Kraus, Georg Ramm, Wai K Lam, Kylie M. Quinn, Lisa M Assmus, Malcolm J. McConville, Luke E. Formosa, Michael T. Ryan, Katherine Kedzierska, Liyen Loh, Carolien E. van de Sandt, Nicole L. La Gruta, Lucy Cooper, Eleanor C Saunders, Tabinda Hussain, Kim L. Good-Jacobson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature Communications
Nature Communications
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2256706f494b8474fb75db00a16a51
http://link.springer.com/article/10.1038/s41467-020-17441-9
http://link.springer.com/article/10.1038/s41467-020-17441-9
Publikováno v:
ASSAY and Drug Development Technologies. 13:389-401
Leishmania species are sandfly-transmitted protozoan parasites that cause a spectrum of diseases, ranging from localized skin lesions to fatal visceral disease, in more than 12 million people worldwide. These parasites primarily target macrophages in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9dfe1166aa580e74104887fc7cf21b1
https://doi.org/10.1089/adt.2015.652
https://doi.org/10.1089/adt.2015.652
Publikováno v:
Bioinformatics
Summary Stable isotope directed metabolomics is increasingly being used to measure metabolic fluxes in microbial, plant and animal cells. Incorporation of 13C/15N isotopes into a wide range of metabolites is typically determined using gas chromatogra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32158570eb7edbf25bc852c8fa7d844
https://pubmed.ncbi.nlm.nih.gov/29360933
https://pubmed.ncbi.nlm.nih.gov/29360933
Autor:
Martin Blume, Michael J Dagley, Joachim Kloehn, Malcolm J. McConville, Simon A. Cobbold, Eleanor C Saunders
Publikováno v:
Current opinion in microbiology. 32
Protozoan parasites have evolved diverse growth and metabolic strategies for surviving and proliferating within different extracellular and intracellular niches in their mammalian hosts. Metabolomic approaches, including high coverage metabolite prof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8866c6b5ce3f331f7f35c82dc7cf512f
https://pubmed.ncbi.nlm.nih.gov/27200489
https://pubmed.ncbi.nlm.nih.gov/27200489
Autor:
Traude H. Beilharz, Thusitha Rupasinghe, Trevor Lithgow, Julianne T. Djordjevic, Filomena Pettolino, Michael J Dagley, Cécile Beaurepaire, Aaron P. Mitchell, Malcolm J. McConville, Ana Traven, Ian E Gentle, Nathalie Uwamahoro, Dedreja L. Tull, Tricia L. Lo, André Nantel
Publikováno v:
Molecular Microbiology. 79:968-989
The cell wall is essential for viability of fungi and is an effective drug target in pathogens such as Candida albicans. The contribution of post-transcriptional gene regulators to cell wall integrity in C. albicans is unknown. We show that the C. al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::441ef809b5cfd1d24f83d2a0b9301c0b
https://doi.org/10.1111/j.1365-2958.2010.07503.x
https://doi.org/10.1111/j.1365-2958.2010.07503.x
Autor:
Anthony W. Purcell, Trevor Lithgow, Vladimir A Likic, Ondrej Smid, Jan Tachezy, Pavel Dolezal, Susan K. Buchanan, Michael J Dagley
Publikováno v:
Molecular Biology and Evolution. 26:1941-1947
The identification of mitosomes in Giardia generated significant debate on the evolutionary origin of these organelles, whether they were highly reduced mitochondria or the product of a unique endosymbiotic event in an amitochondrial organism. As the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae08ebbb5d9b5efb28016be135bdce4
https://doi.org/10.1093/molbev/msp117
https://doi.org/10.1093/molbev/msp117