Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Michael J Booth"'
Autor:
Denis Hartmann, Michael J. Booth
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-8 (2023)
Light-activated antisense oligonucleotides have been developed to induce gene knockdown in living cells, however, their synthesis remains challenging and application in cell-free systems is underexplored. Here, the authors report a one-step method fo
Externí odkaz:
https://doaj.org/article/0d84e3fda91a47cbae6150ab2ac6801c
Publikováno v:
BMC Rheumatology, Vol 5, Iss 1, Pp 1-10 (2021)
Abstract Objective Immune-mediated inflammatory diseases (IMID) are characterized by systemic inflammation affecting the joints and bodily organs. Studies examining the association between individual IMIDs and the risk of Alzheimer’s disease (AD) h
Externí odkaz:
https://doaj.org/article/0f4c6c186888433099890d523dc53996
Publikováno v:
BMC Rheumatology, Vol 5, Iss 1, Pp 1-8 (2021)
Abstract Background Studies suggest an increased prevalence of cognitive impairment (CI) among people with rheumatoid arthritis (RA). However, most prior studies have used convenience samples which are subject to selection biases or have failed to ad
Externí odkaz:
https://doaj.org/article/89de03e45b29419eabdc7b02ee8c6fd1
Publikováno v:
ACR Open Rheumatology, Vol 3, Iss 4, Pp 239-249 (2021)
Objective To determine the validity of self‐reported physician diagnosis of rheumatoid arthritis (RA) using multiple gold‐standard measures based on Medicare claims in a nationally representative sample of older adults and to verify whether addit
Externí odkaz:
https://doaj.org/article/7816ed92e1894b36a1cbfda3c3e2abc7
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2022)
Synthetic cells, which mimic cellular function within a minimal compartment, are finding wide application, for instance in studying cellular communication and as delivery devices to living cells. However, to fully realise the potential of synthetic c
Externí odkaz:
https://doaj.org/article/10c759f5938644b78bf551cac4d5ef37
Publikováno v:
Journal of the American Chemical Society. 145:9471-9480
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e829d871b2ad9959d8fd7fb000a13b9
https://doi.org/10.1021/jacs.3c02350
https://doi.org/10.1021/jacs.3c02350
Autor:
Denis Hartmann, Michael J. Booth
Publikováno v:
Chemical Communications. 59:5685-5688
Topologically constraining antisense oligonucleotides (ASOs) into a handcuff structure, via photocages, silences their activity and opens up the possibility of precise light-controlled regulation of biological systems.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de71947013196f7311621dd9f4d2afeb
https://doi.org/10.1039/d3cc01374j
https://doi.org/10.1039/d3cc01374j
Autor:
Khoa Chung, Michael J Booth
Plasmids are ubiquitous in biology, where they are used to study gene-function relationships and intricate molecular networks, and hold potential as therapeutic devices. Developing methods to control their function will advance their application in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff4a7ce0c39a4acd05795da83aa36ffb
https://doi.org/10.1101/2023.05.26.542478
https://doi.org/10.1101/2023.05.26.542478
Autor:
Layla Malouf, Diana A. Tanase, Giacomo Fabrini, Miguel Paez-Perez, Adrian Leathers, Michael J. Booth, Lorenzo Di Michele
Synthetic cells, like their biological counterparts, require internal compartments with distinct chemical and physical properties where different functionalities can be localised. Inspired by membrane-less compartmentalisation in biological cells, he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e40832670d17e6a51216cb2af330a65c
https://doi.org/10.1101/2023.03.17.533162
https://doi.org/10.1101/2023.03.17.533162
Autor:
Adrian Leathers, Michal Walczak, Ryan A. Brady, Assala Al Samad, Jurij Kotar, Michael J. Booth, Pietro Cicuta, Lorenzo Di Michele
Biological cells display complex internal architectures, with distinct micro environments that establish the chemical heterogeneity needed to sustain cellular functions. The continued efforts to create advanced cell mimics –artificial cells– dema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3daa703822fc1d50a8e351466b57eb7