Zobrazeno 1 - 10 of 202 pro vyhledávání: '"Michael J Barnett"'
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Akademický článek
NlpC/P60 peptidoglycan hydrolases of Trichomonas vaginalis have complementary activities that empower the protozoan to control host-protective lactobacilli.
Autor: Michael J Barnett, Jully Pinheiro, Jeremy R Keown, Jacob Biboy, Joe Gray, Ioana-Wilhelmina Lucinescu, Waldemar Vollmer, Robert P Hirt, Augusto Simoes-Barbosa, David C Goldstone
Publikováno v: PLoS Pathogens, Vol 19, Iss 8, p e1011563 (2023)
Trichomonas vaginalis is a human protozoan parasite that causes trichomoniasis, a prevalent sexually transmitted infection. Trichomoniasis is accompanied by a shift to a dysbiotic vaginal microbiome that is depleted of lactobacilli. Studies on co-cul
Externí odkaz: https://doaj.org/article/1fa6536ce56e459b8ef360e8d10f2ff6
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2
Outpatient Autologous Stem Cell Transplants for Multiple Myeloma: Analysis of Safety and Outcomes in a Tertiary Care Center
Autor: Raewyn Broady, Michael J. Barnett, Stephen H. Nantel, Cynthia L. Toze, Kevin W. Song, Heather J. Sutherland, Wasithep Limvorapitak, Shruthi Kodad, Maryse M. Power, Alina S. Gerrie, Yasser Abou Mourad, David Sanford, Thomas J. Nevill, Donna E. Hogge, Donna L. Forrest, Jennifer White, Sujaatha Narayanan
Publikováno v: Clinical Lymphoma Myeloma and Leukemia. 19:784-790
Background Autologous stem cell transplant (ASCT) is the preferred consolidation strategy to treat eligible patients with multiple myeloma (MM) and related plasma cell dyscrasias. Given the increasing volume of patients and longer wait time, outpatie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744f6a7dfa9fb1d5e843db21f95e3d97
https://doi.org/10.1016/j.clml.2019.09.619
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3
Akademický článek
Germ-line GATA2 p.THR354MET mutation in familial myelodysplastic syndrome with acquired monosomy 7 and ASXL1 mutation demonstrating rapid onset and poor survival
Autor: Csaba Bödör, Aline Renneville, Matthew Smith, Aurélie Charazac, Sameena Iqbal, Pascaline Étancelin, Jamie Cavenagh, Michael J Barnett, Karolina Kramarzová, Biju Krishnan, András Matolcsy, Claude Preudhomme, Jude Fitzgibbon, Carolyn Owen
Publikováno v: Haematologica, Vol 97, Iss 6 (2012)
While most myelodysplastic syndrome/acute myeloid leukemia cases are sporadic, rare familial cases occur and provide some insight into leukemogenesis. The most clearly defined familial cases result from inherited mutations in RUNX1 or CEBPA. Recently
Externí odkaz: https://doaj.org/article/2536ea5e3e664fa4b4b5c5c7d32e8dc6
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5
Excellent real-world outcomes of adults with Burkitt lymphoma treated with CODOX-M/IVAC plus or minus rituximab
Autor: Katie Y. Zhu, Khaled M. Ramadan, Tracy Tucker, Maryse M. Power, Heather A. Leitch, Donna L. Forrest, David Sanford, Graham W. Slack, Stephen H. Nantel, Sujaatha Narayanan, Yasser Abou Mourad, Joseph M. Connors, Heather J. Sutherland, Michael J. Barnett, Raewyn Broady, Cynthia L. Toze, Donna E. Hogge, Kevin W. Song, Alina S. Gerrie, Thomas J. Nevill, Laurie H. Sehn
Publikováno v: British Journal of Haematology. 181:782-790
Treatment of Burkitt lymphoma (BL) with intensive, multi-agent chemotherapy with aggressive central nervous system (CNS) prophylaxis results in high cure rates, although no regimen is standard of care. We examined population-based survival outcomes o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac1860a9da81a35fd6107207c7b7999
https://doi.org/10.1111/bjh.15262
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6
A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5α and mammalian autophagy-related ATG8 proteins
Autor: Moyra M. Black, F. Grant Pearce, Jonathan P. Stoye, J.R. Keown, David C. Goldstone, Aaron K W Ferron, Melvyn W. Yap, Michael J. Barnett
Publikováno v: The Journal of Biological Chemistry
The retroviral restriction factor tripartite motif-containing 5α (Trim5α) acts during the early postentry stages of the retroviral life cycle to block infection by a broad range of retroviruses, disrupting reverse transcription and integration. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a44d354947bf75fca64d39e4c376504
https://ora.ox.ac.uk/objects/uuid:091b9027-22f7-4ab9-af38-2661a0309b2f
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8
Allogeneic Hematopoietic Stem Cell Transplantation Is an Effective Salvage Therapy for Patients with Chronic Myeloid Leukemia Presenting with Advanced Disease or Failing Treatment with Tyrosine Kinase Inhibitors
Autor: Sujaatha Narayanan, Michael J. Barnett, Maryse M. Power, Raewyn Broady, Stephen H. Nantel, Anish Puliyayil Nair, Alina S. Gerrie, Donna L. Forrest, Yasser Abou Mourad, Donna E. Hogge, Heather J. Sutherland, Thomas J. Nevill, Kevin W. Song, Cynthia L. Toze
Publikováno v: Biology of Blood and Marrow Transplantation. 21(8):1437-1444
Allogeneic hematopoietic stem cell transplantation (HSCT) remains the only known curative therapy for chronic myeloid leukemia (CML); however, it is rarely utilized given the excellent long-term results with tyrosine kinase inhibitor (TKI) treatment.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa83e1663167342d4c0bcc1e72422c0b
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9
Targeting Primitive Chronic Myeloid Leukemia Cells by Effective Inhibition of a New AHI-1–BCR-ABL–JAK2 Complex
Autor: Ashley Ringrose, Xiaoyan Jiang, Ralph B. Arlinghaus, James Paul, Heather G. Jørgensen, Jon Stobo, Damian Lai, Ali G. Turhan, Kyi Min Saw, Tessa L. Holyoake, Karen Lambie, Connie J. Eaves, Donna DeGeer, Ivan Sloma, Donna L. Forrest, Matthew T. V. Chan, Min Chen, Hui Mi Wang, Helen Nakamoto, Allen C. Eaves, Paolo Gallipoli, Michael J. Barnett
Publikováno v: JNCI Journal of the National Cancer Institute
The defining hallmark of chronic myeloid leukemia (CML) is the BCR-ABL fusion gene originating in a hematopoietic stem cell (1–4). The BCR-ABL oncoprotein (p210BCR-ABL) encoded by this gene displays constitutively elevated tyrosine kinase (TK) acti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daa7508f42b96ff3887f8c85440246f6
http://europepmc.org/articles/PMC3601953
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