Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michael J Asbury"'
Autor:
Geoffrey R Venning, Joan M Clarke, JR Shelton, Gordon T McInnes, Ian R Harrison, LE Ramsay, Michael J Asbury
Publikováno v:
Clinical pharmacology and therapeutics. 30(2)
The renal antimineralocorticoid activity of single oral doses of a new aldosterone antagonist OH OPC(ME)-K was compared to that of spironolactone in two studies in healthy men. OH OPC(ME)-K reversed the urinary electrolyte response to fludrocortisone
Autor:
JR Shelton, LE Ramsay, GT McInnes, RM Perkins, JM Clarke, IR Harrison, Michael J Asbury, GR Venning
Publikováno v:
British journal of clinical pharmacology. 13(3)
1 The renal antimineralocorticoid potency of single doses of thirteen compounds with properties in animals compatible with competitive aldosterone antagonism was compared to that of spironolactone in healthy men. 2 Twelve compounds showed significant
Publikováno v:
Clinical pharmacology and therapeutics. 21(5)
Relative dose ratios of the mineralocorticoid antagonists spironolactone (100 mg and 200 mg daily) and canrenoate-K (200 mg daily) at steady state were defined in six healthy subjects with fludrecortisone as the mineralocorticoid agonist. The urine l
Autor:
Michael J Asbury, LE Ramsay, Ian R Harrison, JR Shelton, Joan M Clarke, Geoffrey R Venning, Gordon T McInnes
Publikováno v:
Clinical pharmacology and therapeutics. 27(3)
The renal antimineralocorticoid activity of single administration of 2 sulfur-containing compounds, which are thought to be intermediate metabolites of spironolactone, was assessed in healthy subjects. They were each active in reversing the urinary e
Publikováno v:
British Journal of Clinical Pharmacology. 9:295P-296P
Publikováno v:
Journal of Steroid Biochemistry. 8:xx