Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Michael J, Tuvim"'
Autor:
Yongxing Wang, Vikram V Kulkarni, Jezreel Pantaleón García, Miguel M Leiva-Juárez, David L Goldblatt, Fahad Gulraiz, Lisandra Vila Ellis, Jichao Chen, Michael K Longmire, Sri Ramya Donepudi, Philip L Lorenzi, Hao Wang, Lee-Jun Wong, Michael J Tuvim, Scott E Evans
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011138 (2023)
Pneumonia is a worldwide threat, making discovery of novel means to combat lower respiratory tract infection an urgent need. Manipulating the lungs' intrinsic host defenses by therapeutic delivery of certain pathogen-associated molecular patterns pro
Externí odkaz:
https://doaj.org/article/b16611b4866742938bff92c35c629d1c
Autor:
David L. Goldblatt, Gabriella Valverde Ha, Shradha Wali, Vikram V. Kulkarni, Michael K. Longmire, Ana M. Jaramillo, Rosha P. Chittuluru, Adrienne Fouts, Margarita Martinez-Moczygemba, Jonathan T. Lei, David P. Huston, Michael J. Tuvim, Burton F. Dickey, Scott E. Evans
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Allergic asthma is a chronic inflammatory respiratory disease associated with eosinophilic infiltration, increased mucus production, airway hyperresponsiveness, and airway remodeling. Epidemiologic data reveal that the prevalence of allergic sensitiz
Externí odkaz:
https://doaj.org/article/dd1b05bdffe9477f901fdf3109e68501
Autor:
Ying Lai, Michael J. Tuvim, Jeremy Leitz, John Peters, Richard A. Pfuetzner, Luis Esquivies, Qiangjun Zhou, Barbara Czako, Jason B. Cross, Philip Jones, Burton F. Dickey, Axel T. Brunger
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The so-called primary interface between the SNARE complex and synaptotagmin-1 (Syt1) is essential for Ca2+-triggered neurotransmitter release in neuronal synapses. The interacting residues of the primary interface are conserved across different speci
Externí odkaz:
https://doaj.org/article/a5d10121e3a641d6bd7fa03f7507213a
Autor:
Henry Danahay, Roy Fox, Sarah Lilley, Holly Charlton, Kathryn Adley, Lee Christie, Ejaz Ansari, Camille Ehre, Alexis Flen, Michael J. Tuvim, Burton F. Dickey, Colin Williams, Sarah Beaudoin, Stephen P Collingwood, Martin Gosling
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 8, Pp 464-477 (2020)
Abstract The calcium‐activated chloride channel (CaCC) TMEM16A enables chloride secretion across several transporting epithelia, including in the airways. Additional roles for TMEM16A have been proposed, which include regulating mucus production an
Externí odkaz:
https://doaj.org/article/83ed811c2488412dac57b82211c99ada
Autor:
Sebastian L. Johnston, David L. Goldblatt, Scott E. Evans, Michael J. Tuvim, Burton F. Dickey
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Besides providing an essential protective barrier, airway epithelial cells directly sense pathogens and respond defensively. This is a frontline component of the innate immune system with specificity for different pathogen classes. It occurs in the c
Externí odkaz:
https://doaj.org/article/c1b95d1322db4000acdcfad1d0d43dc5
Autor:
Oanh N. Hoang, Anna Ermund, Ana M. Jaramillo, Dalia Fakih, Cory B. French, Jose R. Flores, Harry Karmouty-Quintana, Jesper M. Magnusson, Giorgio Fois, Michael Fauler, Manfred Frick, Peter Braubach, Joshua B. Hales, Richard C. Kurten, Reynold Panettieri, Leoncio Vergara, Camille Ehre, Roberto Adachi, Michael J. Tuvim, Gunnar C. Hansson, Burton F. Dickey
Publikováno v:
American journal of respiratory and critical care medicine. 206(9)
Autor:
Belinda J. Hernandez, Margo P. Cain, Anne M. Lynch, Jose R. Flores, Michael J. Tuvim, Burton F. Dickey, Jichao Chen
Publikováno v:
Am J Respir Cell Mol Biol
The lung epithelium forms the first barrier against respiratory pathogens and noxious chemicals; however, little is known about how more than 90% of this barrier, made of AT1 (alveolar type 1) cells, responds to injury. Using the Sendai virus to mode
Autor:
Carson T. Kirkpatrick, Yongxing Wang, Miguel M. Leiva Juarez, Pooja Shivshankar, Jezreel Pantaleón García, Alexandria K. Plumer, Vikram V. Kulkarni, Hayden H. Ware, Fahad Gulraiz, Miguel A. Chavez Cavasos, Gabriela Martinez Zayas, Shradha Wali, Andrew P. Rice, Hongbing Liu, James M. Tour, William K. A. Sikkema, Ana S. Cruz Solbes, Keith A. Youker, Michael J. Tuvim, Burton F. Dickey, Scott E. Evans
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
Externí odkaz:
https://doaj.org/article/df8541068a8445818a2d6e6013048203
Autor:
Yongxing Wang, Vikram V. Kulkarni, Jezreel Pantaleón García, Miguel M. Leiva-Juárez, David L. Goldblatt, Fahad Gulraiz, Jichao Chen, Sri Ramya Donepudi, Philip L. Lorenzi, Hao Wang, Lee-Jun Wong, Michael J. Tuvim, Scott E. Evans
Publikováno v:
bioRxiv
Pneumonia is a worldwide threat, making discovery of novel means to combat lower respiratory tract infections an urgent need. We have previously shown that manipulating the lungs’ intrinsic host defenses by therapeutic delivery of a unique dyad of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0816ffd156a236fe88c2d4d0cf296fe8
https://doi.org/10.1101/2023.01.19.524841
https://doi.org/10.1101/2023.01.19.524841
Autor:
Eduardo I. Cardenas, Keegan Breaux, Qi Da, Jose R. Flores, Marco A. Ramos, Michael J. Tuvim, Alan R. Burns, Rolando E. Rumbaut, Roberto Adachi
Publikováno v:
Haematologica, Vol 103, Iss 7 (2018)
Platelet degranulation is crucial for hemostasis and may participate in inflammation. Exocytosis in platelets is mediated by SNARE proteins and should be controlled by Munc13 proteins. We found that platelets express Munc13-2 and -4. We assessed plat
Externí odkaz:
https://doaj.org/article/7bb1b5d4b2e5449f9426ef5f0712b170