Zobrazeno 1 - 10
of 406
pro vyhledávání: '"Michael J, Strong"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
The progressive degeneration of motor neurons in amyotrophic lateral sclerosis (ALS) is accompanied by the formation of a broad array of cytoplasmic and nuclear neuronal inclusions (protein aggregates) largely containing RNA-binding proteins such as
Externí odkaz:
https://doaj.org/article/f05e58e2e4c44623952c03fca6ab3b68
Autor:
Erin Santandrea, Farhang Aliakbari, Emily Truscott, Lynda McCaig, Neil S. Donison, Danielle Graham, Michael J. Strong, Kathryn Volkening
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-6 (2024)
Abstract Ethical animal use follows the 3R’s: Replacement, Reduction and Refinement. Here, we present the use of simultaneous jugular vein and cisterna magna catheterization via a port system in rats for repeated fluid sampling for 14 consecutive d
Externí odkaz:
https://doaj.org/article/3a60acbbf2c14d86bd7a9e0e73227a25
Autor:
Joseph R. Linzey, Varun G. Kathawate, Michael J. Strong, Kayla Roche, Peyton E. Goethe, Lila R. Tudrick, Johan Lee, Arushi Tripathy, Sravanthi Koduri, Ayobami L. Ward, Oludotun Ogunsola, Mark M. Zaki, Rushikesh S. Joshi, Grant Weyburne, Charles S. Mayo, Joseph R. Evans, William C. Jackson, Nicholas J. Szerlip
Publikováno v:
Cancer Medicine, Vol 12, Iss 19, Pp 20177-20187 (2023)
Abstract Background As cancer therapies have improved, spinal metastases are increasingly common. Resulting complications have a significant impact on patient's quality of life. Optimal methods of surveillance and avoidance of neurologic deficits are
Externí odkaz:
https://doaj.org/article/2dc5d62a929943719618737080a66a75
Publikováno v:
Non-Coding RNA, Vol 10, Iss 2, p 23 (2024)
Paraspeckles are nuclear condensates formed by NEAT1_2 lncRNA and different RNA-binding proteins. In general, these membraneless organelles function in the regulation of gene expression and translation and in miRNA processing, and in doing this, they
Externí odkaz:
https://doaj.org/article/a3019715d73248829d0ffb1c224bd259
Autor:
Neil Donison, Matthew Hintermayer, Maegha Subramaniam, Erin Santandrea, Kathryn Volkening, Michael J. Strong
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Phosphorylated microtubule-associated protein tau (tau) aggregates are a pathological hallmark of various neurodegenerative diseases, including chronic traumatic encephalopathy and amyotrophic lateral sclerosis with cognitive impairment. While there
Externí odkaz:
https://doaj.org/article/2299cbd01d6043df929240c2af22b231
Autor:
Xiaoyun Xu, Matthew Cowan, Flavio Beraldo, Amy Schranz, Patrick McCunn, Nicole Geremia, Zalman Brown, Maitray Patel, Karen L. Nygard, Reza Khazaee, Lihong Lu, Xingyu Liu, Michael J. Strong, Gregory A. Dekaban, Ravi Menon, Robert Bartha, Mark Daley, Haojie Mao, Vania Prado, Marco A. M. Prado, Lisa Saksida, Tim Bussey, Arthur Brown
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-27 (2021)
Abstract We have previously reported long-term changes in the brains of non-concussed varsity rugby players using magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI) and functional magnetic imaging (fMRI). Others have reported cogni
Externí odkaz:
https://doaj.org/article/8a4b058cb2f44d0f99bb08a4296f09b7
Autor:
Qinyan Yin, Michael J. Strong, Yan Zhuang, Erik K. Flemington, Naftali Kaminski, Joao A. de Andrade, Joseph A. Lasky
Publikováno v:
BMC Pulmonary Medicine, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Numerous publications suggest an association between herpes virus infection and idiopathic pulmonary fibrosis (IPF). These reports have employed immunohistochemistry, in situ hybridization and/or PCR, which are susceptible to spec
Externí odkaz:
https://doaj.org/article/c0d9633dd7e040e2b1a124f8a42f37e3
Autor:
Aqila A Ahmed, Michael J Strong, Xiaofeng Zhou, Tyler Robinson, Sabrina Rocco, Geoffrey W Siegel, Gregory A Clines, Bethany B Moore, Evan T Keller, Nicholas J Szerlip
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0267642 (2022)
Roughly 400,000 people in the U.S. are living with bone metastases, the vast majority occurring in the spine. Metastases to the spine result in fractures, pain, paralysis, and significant health care costs. This predilection for cancer to metastasize
Externí odkaz:
https://doaj.org/article/a60036ad42f9468994f662df7dc31962
Autor:
Cristian A. Droppelmann, Danae Campos-Melo, Alexander J. Moszczynski, Hind Amzil, Michael J. Strong
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract Amyotrophic lateral sclerosis (ALS) is a devastating progressive neurodegenerative disease with no known etiology. The formation of pathological protein inclusions, including RNA-binding proteins such as TDP-43 and rho guanine nucleotide exc
Externí odkaz:
https://doaj.org/article/8e05139623084174b31f8c9097aface9
Autor:
Shuai Liang, Derek Beaton, Stephen R. Arnott, Tom Gee, Mojdeh Zamyadi, Robert Bartha, Sean Symons, Glenda M. MacQueen, Stefanie Hassel, Jason P. Lerch, Evdokia Anagnostou, Raymond W. Lam, Benicio N. Frey, Roumen Milev, Daniel J. Müller, Sidney H. Kennedy, Christopher J. M. Scott, The ONDRI Investigators, Stephen C. Strother, Angela Troyer, Anthony E. Lang, Barry Greenberg, Chris Hudson, Dale Corbett, David A. Grimes, David G. Munoz, Douglas P. Munoz, Elizabeth Finger, J. B. Orange, Lorne Zinman, Manuel Montero-Odasso, Maria Carmela Tartaglia, Mario Masellis, Michael Borrie, Michael J. Strong, Morris Freedman, Paula M. McLaughlin, Richard H. Swartz, Robert A. Hegele, Sandra E. Black, William E. McIlroy
Publikováno v:
Frontiers in Neuroinformatics, Vol 15 (2021)
Despite the wide application of the magnetic resonance imaging (MRI) technique, there are no widely used standards on naming and describing MRI sequences. The absence of consistent naming conventions presents a major challenge in automating image pro
Externí odkaz:
https://doaj.org/article/b987f8f10e054d3e9bc11ba9f80a144f