Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Michael J, Ricciardi"'
Autor:
Brandon C. Rosen, Kaitlin Sawatzki, Michael J. Ricciardi, Elise Smith, Inah Golez, Jack T. Mauter, Núria Pedreño-López, Aaron Yrizarry-Medina, Kim L. Weisgrau, Logan J. Vosler, Thomas B. Voigt, Johan J. Louw, Jennifer Tisoncik-Go, Leanne S. Whitmore, Christakis Panayiotou, Noor Ghosh, Jessica R. Furlott, Christopher L. Parks, Ronald C. Desrosiers, Jeffrey D. Lifson, Eva G. Rakasz, David I. Watkins, Michael Gale
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSpontaneous control of chronic-phase HIV/SIV viremia is often associated with the expression of specific MHC class I allotypes. HIV/SIV-specific CD8+ cytotoxic T lymphocytes (CTLs) restricted by these MHC class I allotypes appear to be cr
Externí odkaz:
https://doaj.org/article/a278c58415384153962a8239ac4c5dc6
Autor:
Fangzhu Zhao, Celina Keating, Gabriel Ozorowski, Namir Shaabani, Irene M. Francino-Urdaniz, Shawn Barman, Oliver Limbo, Alison Burns, Panpan Zhou, Michael J. Ricciardi, Jordan Woehl, Quoc Tran, Hannah L. Turner, Linghang Peng, Deli Huang, David Nemazee, Raiees Andrabi, Devin Sok, John R. Teijaro, Timothy A. Whitehead, Andrew B. Ward, Dennis R. Burton, Joseph G. Jardine
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104914- (2022)
Summary: The rapid spread of SARS-CoV-2 variants poses a constant threat of escape from monoclonal antibody and vaccine countermeasures. Mutations in the ACE2 receptor binding site on the surface S protein have been shown to disrupt antibody binding
Externí odkaz:
https://doaj.org/article/248cba15fce54b88a8bce360835a4e07
Autor:
Cássia G. T. Silveira, Diogo M. Magnani, Priscilla R. Costa, Vivian I. Avelino-Silva, Michael J. Ricciardi, Maria do Carmo S. T. Timenetsky, Raphaella Goulart, Carolina A. Correia, Mariana P. Marmorato, Lilian Ferrari, Zelinda B. Nakagawa, Claudia Tomiyama, Helena Tomiyama, Jorge Kalil, Ricardo Palacios, Alexander R. Precioso, David I. Watkins, Esper G. Kallás
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
An effective vaccine against the dengue virus (DENV) should induce a balanced, long-lasting antibody (Ab) response against all four viral serotypes. The burst of plasmablasts in the peripheral blood after vaccination may reflect enriched vaccine-spec
Externí odkaz:
https://doaj.org/article/f79ebe28522144e8bb445ccb7d47e353
Autor:
Nuria Pedreño-Lopez, Michael J. Ricciardi, Brandon C. Rosen, Ge Song, Raiees Andrabi, Dennis R. Burton, Eva G. Rakasz, David I. Watkins
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 781-790 (2020)
Simian immunodeficiency virus (SIV) infection of Indian rhesus macaques (RMs) is one of the best-characterized animal models for human immunodeficiency virus (HIV) infection. Monoclonal antibodies (mAbs) have shown promise for prevention and treatmen
Externí odkaz:
https://doaj.org/article/5a70f718f1e1409096c9cf4d050ebc8c
Autor:
Nuria Pedreño-Lopez, Christine M. Dang, Brandon C. Rosen, Michael J. Ricciardi, Varian K. Bailey, Martin J. Gutman, Lucas Gonzalez-Nieto, Matthias G. Pauthner, Khoa Le, Ge Song, Raiees Andrabi, Kim L. Weisgrau, Nicholas Pomplun, José M. Martinez-Navio, Sebastian P. Fuchs, Jens Wrammert, Eva G. Rakasz, Jeffrey D. Lifson, Mauricio A. Martins, Dennis R. Burton, David I. Watkins, Diogo M. Magnani
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 16, Iss , Pp 225-237 (2020)
Structural characterization of the HIV-1 Envelope (Env) glycoprotein has facilitated the development of Env probes to isolate HIV-specific monoclonal antibodies (mAbs). However, preclinical studies have largely evaluated these virus-specific mAbs aga
Externí odkaz:
https://doaj.org/article/583e2f5e1bdc4c94b11792ddc7103b3a
Publikováno v:
ACS Omega, Vol 4, Iss 4, Pp 6808-6818 (2019)
Externí odkaz:
https://doaj.org/article/27dd3b22d3394fd2a6298aa0cf7b7435
Autor:
Nuria Pedreño-Lopez, Brandon C. Rosen, Walter J. Flores, Matthew J. Gorman, Thomas B. Voigt, Michael J. Ricciardi, Kristin Crosno, Kim L. Weisgrau, Christopher L. Parks, Jeffrey D. Lifson, Galit Alter, Eva G. Rakasz, Diogo M. Magnani, Mauricio A. Martins, David I. Watkins
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The antiviral properties of broadly neutralizing antibodies against HIV are well-documented but no vaccine is currently able to elicit protective titers of these responses in primates. While current vaccine modalities can readily induce non-neutraliz
Externí odkaz:
https://doaj.org/article/953611f23bac4fb3b5b40dc083c6c0d6
Autor:
Brandon C. Rosen, Nuria Pedreño-Lopez, Michael J. Ricciardi, Jason S. Reed, Jonah B. Sacha, Eva G. Rakasz, David I. Watkins
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
CD8+ cytotoxic T lymphocytes (CTLs) exert potent antiviral activity after HIV/SIV infection. However, efforts to harness the antiviral efficacy of CTLs for HIV/SIV prophylaxis and therapy have been severely hindered by two major problems: viral escap
Externí odkaz:
https://doaj.org/article/134aa1a3a121485ab813ba24be22cd4c
Autor:
Diogo M. Magnani, Thomas F. Rogers, Nicholas J. Maness, Nathan D. Grubaugh, Nathan Beutler, Varian K. Bailey, Lucas Gonzalez-Nieto, Martin J. Gutman, Núria Pedreño-Lopez, Jaclyn M. Kwal, Michael J. Ricciardi, Tereance A. Myers, Justin G. Julander, Rudolf P. Bohm, Margaret H. Gilbert, Faith Schiro, Pyone P. Aye, Robert V. Blair, Mauricio A. Martins, Kathrine P. Falkenstein, Amitinder Kaur, Christine L. Curry, Esper G. Kallas, Ronald C. Desrosiers, Pascal J. Goldschmidt-Clermont, Stephen S. Whitehead, Kristian G. Andersen, Myrna C. Bonaldo, Andrew A. Lackner, Antonito T. Panganiban, Dennis R. Burton, David I. Watkins
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Zika virus (ZIKV) infection in pregnant women has been associated with fetal developmental defects. Here, the authors show that a Brazilian ZIKV isolate causes fetal demise in non-human primates and that antibody treatment at time of peak viremia is
Externí odkaz:
https://doaj.org/article/6ca8c5f99d854de99a13b95f4edccb07
Autor:
Lucas Gonzalez-Nieto, Isabelle M Castro, Georg F Bischof, Young C Shin, Michael J Ricciardi, Varian K Bailey, Christine M Dang, Nuria Pedreño-Lopez, Diogo M Magnani, Keisuke Ejima, David B Allison, Hwi Min Gil, David T Evans, Eva G Rakasz, Jeffrey D Lifson, Ronald C Desrosiers, Mauricio A Martins
Publikováno v:
PLoS Pathogens, Vol 15, Iss 9, p e1008015 (2019)
A prophylactic vaccine against human immunodeficiency virus (HIV) remains a top priority in biomedical research. Given the failure of conventional immunization protocols to confer robust protection against HIV, new and unconventional approaches may b
Externí odkaz:
https://doaj.org/article/7e6e831fadc24404a14cf0b3646c06d4