Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Michael J, Morowitz"'
Autor:
Matthew B. Rogers, Ashley Harner, Megan Buhay, Brian Firek, Barbara Methé, Alison Morris, Octavia M. Peck Palmer, Susan B. Promes, Robert L. Sherwin, Lauren Southerland, Alexandre R. Vieira, Sachin Yende, Michael J. Morowitz, David T. Huang
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/27ed1be248d349bba86119c4b837a437
Publikováno v:
Cells, Vol 13, Iss 9, p 733 (2024)
Self-renewal and differentiation are two characteristics of hematopoietic stem cells (HSCs). Under steady physiological conditions, most primitive HSCs remain quiescent in the bone marrow (BM). They respond to different stimuli to refresh the blood s
Externí odkaz:
https://doaj.org/article/968601e8d79a45c38cbbbd0f266069e9
Autor:
Yue Clare Lou, Jordan Hoff, Matthew R. Olm, Jacob West-Roberts, Spencer Diamond, Brian A. Firek, Michael J. Morowitz, Jillian F. Banfield
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Background Metagenomics analyses can be negatively impacted by DNA contamination. While external sources of contamination such as DNA extraction kits have been widely reported and investigated, contamination originating within the study itse
Externí odkaz:
https://doaj.org/article/08a002dbee094fb5b2ab39b7a014e7e3
Autor:
Elizabeth A. Novak, Erin C. Crawford, Heather L. Mentrup, Brian D. Griffith, David M. Fletcher, Meredith R. Flanagan, Corinne Schneider, Brian Firek, Matthew B. Rogers, Michael J. Morowitz, Jon D. Piganelli, Qian Wang, Kevin P. Mollen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionWe have previously demonstrated that a pathologic downregulation of peroxisome proliferator-activated receptor–gamma coactivator 1-alpha (PGC1α) within the intestinal epithelium contributes to the pathogenesis of inflammatory bowel dis
Externí odkaz:
https://doaj.org/article/5b88d11b8ec04e81b726e0f4d2e82ab3
Autor:
Samantha L. Peters, Adair L. Borges, Richard J. Giannone, Michael J. Morowitz, Jillian F. Banfield, Robert L. Hettich
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-7 (2022)
Previous bioinformatic analyses have indicated that bacteriophages can use genetic codes different from those of their host bacteria. Here, Peters et al. use metaproteomics to provide experimental evidence of reassignment of stop codon TAG to glutami
Externí odkaz:
https://doaj.org/article/cab0dea2128d4a5ead2a5e0cb6ee48a9
Autor:
Michael J. Morowitz, Anup C. Katheria, Richard A. Polin, Elizabeth Pace, David T. Huang, Chung-Chou H. Chang, Johathan G. Yabes
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Early-onset sepsis is an important cause of neonatal morbidity and mortality in the preterm population. Infants perceived to be at increased risk for early-onset sepsis are often treated empirically with broad-spectrum antibiotics
Externí odkaz:
https://doaj.org/article/7c7e8ddc200241528d043023689d5e9c
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
While prompt initiation of antibiotics at birth due to concerns for early onset sepsis is common, it often leads to many preterm infants being exposed to treatment despite negative blood cultures. Such exposure to early antibiotics can impact the dev
Externí odkaz:
https://doaj.org/article/9a0a6683c83a461e9b651a7949c944df
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The human gut microbiome, which develops and stabilizes during the early stages of infant life, plays an essential role in host health through the production of metabolic resources and the stimulation and training of the immune system. To study colon
Externí odkaz:
https://doaj.org/article/d1d84b971ee34b809a7d8b61222b2160
Autor:
Patrick T. West, Samantha L. Peters, Matthew R. Olm, Feiqiao B. Yu, Haley Gause, Yue Clare Lou, Brian A. Firek, Robyn Baker, Alexander D. Johnson, Michael J. Morowitz, Robert L. Hettich, Jillian F. Banfield
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Background Candida parapsilosis is a common cause of invasive candidiasis, especially in newborn infants, and infections have been increasing over the past two decades. C. parapsilosis has been primarily studied in pure culture, leaving gaps
Externí odkaz:
https://doaj.org/article/613fb6973098467990e4a5ad5b678134
Autor:
Yue Clare Lou, Matthew R. Olm, Spencer Diamond, Alexander Crits-Christoph, Brian A. Firek, Robyn Baker, Michael J. Morowitz, Jillian F. Banfield
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 9, Pp 100393- (2021)
Summary: Gut microbiome succession affects infant development. However, it remains unclear what factors promote persistence of initial bacterial colonizers in the developing gut. Here, we perform strain-resolved analyses to compare gut colonization o
Externí odkaz:
https://doaj.org/article/2ca86e77c5c748c4acd1cc126bd935ec