Zobrazeno 1 - 10
of 551
pro vyhledávání: '"Michael J, Kerin"'
Autor:
Patrick W Owens, Terri Patricia McVeigh, Nicola Miller, Carole Guerin, Frederic Sebag, Denis Quill, Marcia Bell, Michael J Kerin, Aoife J Lowery
Publikováno v:
Endocrine Oncology, Vol 1, Iss 1, Pp 1-8 (2023)
Objective: FOXE1 is an intronless gene on chromosome 9 which plays a significant role in thyroid morphogenesis. Mutations in FOXE1 are associated with thyroid phenotypes including congenital hypothyroidism, thyroid dysgenesis and thyroid cancer. This
Externí odkaz:
https://doaj.org/article/1f0d12821d494707922871d55dae5ffe
Autor:
Peter McAnena, Brian M. Moloney, Robert Browne, Niamh O’Halloran, Leon Walsh, Sinead Walsh, Declan Sheppard, Karl J. Sweeney, Michael J. Kerin, Aoife J. Lowery
Publikováno v:
BMC Medical Imaging, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Medical image analysis has evolved to facilitate the development of methods for high-throughput extraction of quantitative features that can potentially contribute to the diagnostic and treatment paradigm of cancer. There is a nee
Externí odkaz:
https://doaj.org/article/bb207985a9364540a4bd797036b73cf4
Autor:
Eoin P. Kerin, Matthew G. Davey, Ray P. McLaughlin, Karl J. Sweeney, Michael K. Barry, Carmel M. Malone, Sami Abd Elwahab, Aoife J. Lowery, Michael J. Kerin
Publikováno v:
Breast, Vol 66, Iss , Pp 227-235 (2022)
Introduction: Traditionally, Nottingham prognostic index (NPI) informed prognosis in patients with estrogen receptor positive, human epidermal growth factor receptor-2 negative, node negative (ER+/HER2-/LN-) breast cancer. At present, OncotypeDX© Re
Externí odkaz:
https://doaj.org/article/6d36598accc84767a1ca1b4ac71d4b3f
Autor:
Amirhossein Jalali, David Miresse, Matthew R. Fahey, Niamh Ni Mhaonaigh, Andrew McGuire, Emer Bourke, Michael J. Kerin, James A. L. Brown
Publikováno v:
Current Oncology, Vol 29, Iss 10, Pp 7512-7523 (2022)
Breast cancer represents a heterogeneous condition in which the interaction between host immune response and primary oncogenic events can impact disease progression. Ratios of systemic blood-based immunocytes have emerged as clinically-relevant progn
Externí odkaz:
https://doaj.org/article/91167e5e32da448fb6ed12c82562938d
Autor:
Matthew G. Davey, Gerard Feeney, Heidi Annuk, Maxwell Paganga, Emma Holian, Aoife J. Lowery, Michael J. Kerin, Nicola Miller
Publikováno v:
Gastrointestinal Disorders, Vol 4, Iss 3, Pp 190-204 (2022)
Introduction: One-third of colorectal cancer (CRC) patients present with advanced disease, and establishing control remains a challenge. Identifying novel biomarkers to facilitate earlier diagnosis is imperative in enhancing oncological outcomes. We
Externí odkaz:
https://doaj.org/article/dbdefd9ff9ee4daabe3c6218c3e1136c
Autor:
Matthew G. Davey, Ciara M. Davey, Luis Bouz, Eoin Kerin, Carson McFeetors, Aoife J. Lowery, Michael J. Kerin
Publikováno v:
Breast, Vol 64, Iss , Pp 41-46 (2022)
Introduction: The 21-gene assay provides prognostication for estrogen receptor positive, human epidermal growth factor receptor-2 negative (ER+/HER2-) early female breast cancer patients. This signature has not been validated in male breast cancer (M
Externí odkaz:
https://doaj.org/article/b593074ff6694140a3278072c11969e5
Autor:
Matthew G. Davey, John P.M. O'Donnell, Michael R. Boland, Éanna J. Ryan, Stewart R. Walsh, Michael J. Kerin, Aoife J. Lowery
Publikováno v:
Breast, Vol 62, Iss , Pp 103-113 (2022)
Purpose: Mammographic screening programmes have increased detection rates of non-palpable breast cancers. In these cases, wire-guided localization (WGL) is the most common approach used to guide breast conserving surgery (BCS). Several RCTs have comp
Externí odkaz:
https://doaj.org/article/ca6fa897877040b0ba32f7a9c64dc4c8
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-17 (2022)
Abstract Breast cancer continues to be a major global problem with significant mortality associated with advanced stage and metastases at clinical presentation. However, several findings suggest that metastasis is indeed an early occurrence. The stan
Externí odkaz:
https://doaj.org/article/1340c1a947b14acb9885b963a442f5f3
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 3007 (2023)
Breast cancer is a heterogeneous disease highlighted by the presence of multiple tumor variants and the basal-like breast cancer (BLBC) is considered to be the most aggressive variant with limited therapeutics and a poor prognosis. Though the absence
Externí odkaz:
https://doaj.org/article/0393f55a43b346bd81d9b8f46e080f31
Publikováno v:
Breast, Vol 61, Iss , Pp 1-10 (2022)
Meta-analysis of >87,000 patients demonstrates that patients with invasive lobular carcinoma of the breast are far less likely to achieve pCR of the breast or axilla compared to their ductal counterparts, receive less BCS and more frequently return p
Externí odkaz:
https://doaj.org/article/a5f6026ac12d4487a2bdc790bef67ce5