Výsledky vyhledávání - "Michael J, Grey"

Akademický článek

p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP

Autor: Hanyue Ouyang, Shuang Wu, Wangji Li, Michael J. Grey, Wenchao Wu, Steen H. Hansen

Publikováno v: Cell Reports, Vol 42, Iss 12, Pp 113486- (2023)

Summary: ARHGAP35, which encodes p190A RhoGAP (p190A), is a major cancer gene. p190A is a tumor suppressor that activates the Hippo pathway. p190A was originally cloned via direct binding to p120 RasGAP (RasGAP). Here, we determine that interaction o

Externí odkaz: https://doaj.org/article/5984d7b2c84848beb239d1f7bdd79686

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Akademický článek

Gut microbiota regulation of P-glycoprotein in the intestinal epithelium in maintenance of homeostasis

Autor: Sage E. Foley, Christine Tuohy, Merran Dunford, Michael J. Grey, Heidi De Luca, Caitlin Cawley, Rose L. Szabady, Ana Maldonado-Contreras, Jean Marie Houghton, Doyle V. Ward, Randall J. Mrsny, Beth A. McCormick

Publikováno v: Microbiome, Vol 9, Iss 1, Pp 1-17 (2021)

Abstract Background P-glycoprotein (P-gp) plays a critical role in protection of the intestinal epithelia by mediating efflux of drugs/xenobiotics from the intestinal mucosa into the gut lumen. Recent studies bring to light that P-gp also confers a c

Externí odkaz: https://doaj.org/article/91d5522180234af2941f779d05d4a612

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Akademický článek

The epithelial-specific ER stress sensor ERN2/IRE1β enables host-microbiota crosstalk to affect colon goblet cell development

Autor: Michael J. Grey, Heidi De Luca, Doyle V. Ward, Irini A.M. Kreulen, Katlynn Bugda Gwilt, Sage E. Foley, Jay R. Thiagarajah, Beth A. McCormick, Jerrold R. Turner, Wayne I. Lencer

Publikováno v: The Journal of Clinical Investigation, Vol 132, Iss 17 (2022)

Epithelial cells lining mucosal surfaces of the gastrointestinal and respiratory tracts uniquely express ERN2/IRE1β, a paralogue of the most evolutionarily conserved endoplasmic reticulum stress sensor, ERN1/IRE1α. How ERN2 functions at the host-en

Externí odkaz: https://doaj.org/article/b6a3451037ac41be97dfd02c6d12fa5c

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Akademický článek

Functional Strength Training and Movement Performance Therapy for Upper Limb Recovery Early Poststroke—Efficacy, Neural Correlates, Predictive Markers, and Cost-Effectiveness: FAST-INdiCATE Trial

Autor: Susan M. Hunter, Heidi Johansen-Berg, Nick Ward, Niamh C. Kennedy, Elizabeth Chandler, Christopher John Weir, John Rothwell, Alan M. Wing, Michael J. Grey, Garry Barton, Nick Malachy Leavey, Claire Havis, Roger N. Lemon, Jane Burridge, Amy Dymond, Valerie M. Pomeroy

Publikováno v: Frontiers in Neurology, Vol 8 (2018)

BackgroundVariation in physiological deficits underlying upper limb paresis after stroke could influence how people recover and to which physical therapy they best respond.ObjectivesTo determine whether functional strength training (FST) improves upp

Externí odkaz: https://doaj.org/article/1d591b5d1483407888edbe06d8e8e7d2

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Akademický článek

The TMS Motor Map Does Not Change Following a Single Session of Mirror Training Either with Or without Motor Imagery

Autor: Mark van de Ruit, Michael J. Grey

Publikováno v: Frontiers in Human Neuroscience, Vol 11 (2017)

Both motor imagery and mirror training have been used in motor rehabilitation settings to promote skill learning and plasticity. As motor imagery and mirror training are suggested to be closely linked, it was hypothesized that mirror training augment

Externí odkaz: https://doaj.org/article/e6ec7d67a5f244449eda248cc5be5537

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Akademický článek

Intra and inter-session reliability of rapid Transcranial Magnetic Stimulation stimulus-response curves of tibialis anterior muscle in healthy older adults.

Autor: Elisabetta Peri, Emilia Ambrosini, Vera Maria Colombo, Mark van de Ruit, Michael J Grey, Marco Monticone, Giorgio Ferriero, Alessandra Pedrocchi, Giancarlo Ferrigno, Simona Ferrante

Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0184828 (2017)

The clinical use of Transcranial Magnetic Stimulation (TMS) as a technique to assess corticospinal excitability is limited by the time for data acquisition and the measurement variability. This study aimed at evaluating the reliability of Stimulus-Re

Externí odkaz: https://doaj.org/article/b6e56d7d2d3b4ea0b39d084371acbfb6

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