Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Michael J, Gebhardt"'
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Acinetobacter baumannii is an important pathogen of nosocomial infection. Recently, a group of genes, named “gig” (for Growth in Galleria), have been identified in a contemporary multi-drug resistant clinical isolate of A. baumannii—strain AB50
Externí odkaz:
https://doaj.org/article/302028e951ec4aa5b60cbc1ac87d6ad8
Autor:
Alyssa C Walker, Rohan Bhargava, Alfonso S Vaziriyan-Sani, Christine Pourciau, Emily T Donahue, Autumn S Dove, Michael J Gebhardt, Garrett L Ellward, Tony Romeo, Daniel M Czyż
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009510 (2021)
Protein conformational diseases are characterized by misfolding and toxic aggregation of metastable proteins, often culminating in neurodegeneration. Enteric bacteria influence the pathogenesis of neurodegenerative diseases; however, the complexity o
Externí odkaz:
https://doaj.org/article/b18eceb2fd084df1bd4b043669a19555
Autor:
Michael J. Gebhardt, Elizabeth A. Farland, Pallabi Basu, Keven Macareno, Sahar Melamed, Simon L. Dove
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The RNA chaperone Hfq plays important regulatory roles in many bacteria by facilitating the base pairing between small RNAs (sRNAs) and their cognate mRNA targets. In the gram-negative opportunistic pathogen Pseudomonas aeruginosa , over a hundred pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a468f99ced2d322055953fcb9e0b04b
https://doi.org/10.1073/pnas.2218407120
https://doi.org/10.1073/pnas.2218407120
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(46)
Although the mechanism by which the cyclic AMP receptor protein (CRP) regulates global gene transcription has been intensively studied for decades, new discoveries remain to be made. Here, we report that, during rapid growth, CRP associates with both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05acc4f136e677403d5f0230a3535ddf
https://pubmed.ncbi.nlm.nih.gov/36343262
https://pubmed.ncbi.nlm.nih.gov/36343262
Autor:
Jacob A. Gibson, Michael J. Gebhardt, Renato E. R. S. Santos, Simon L. Dove, Paula I. Watnick
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Although the mechanism by which the cyclic AMP receptor protein (CRP) regulates global gene transcription has been intensively studied for decades, new discoveries remain to be made. Here, we report that, during rapid growth, CRP associates with both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bab9168b940925875d7b91cbdbd762d
https://doi.org/10.1073/pnas.2210115119
https://doi.org/10.1073/pnas.2210115119
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173116 (2017)
The development of plasmid-mediated gene expression control in bacteria revolutionized the field of bacteriology. Many of these expression control systems rely on the addition of small molecules, generally metabolites or non-metabolized analogs there
Externí odkaz:
https://doaj.org/article/a124dbe27afb4faca81549e9dd56414b
Publikováno v:
Mol Microbiol
The H-NS-like proteins MvaT and MvaU act coordinately as global repressors in Pseudomonas aeruginosa by binding to AT-rich regions of the chromosome. Although cells can tolerate loss of either protein, identifying their combined regulatory effects ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fa9b70dcd03e1d5a2e94d56a7fc35b
https://doi.org/10.1111/mmi.14656
https://doi.org/10.1111/mmi.14656
Publikováno v:
Proc Natl Acad Sci U S A
In the opportunistic pathogen Pseudomonas aeruginosa , RsmA is an RNA-binding protein that plays critical roles in the control of virulence, interbacterial interactions, and biofilm formation. Although RsmA is thought to exert its regulatory effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33dc53affb7e0efb4c647df8ffec489
https://doi.org/10.1073/pnas.1917587117
https://doi.org/10.1073/pnas.1917587117
Autor:
Michael J. Gebhardt, Larry A. Gallagher, Rachael K. Jacobson, Elena A. Usacheva, Lance R. Peterson, Daniel V. Zurawski, Howard A. Shuman
Publikováno v:
mBio, Vol 6, Iss 6 (2015)
ABSTRACT The increasing emergence of antibiotic-resistant bacterial pathogens represents a serious risk to human health and the entire health care system. Many currently circulating strains of Acinetobacter baumannii exhibit resistance to multiple an
Externí odkaz:
https://doaj.org/article/adaa6ebb120140d7b347b39fe1bbc406
Autor:
Michael J. Gebhardt, Larry A. Gallagher, Joseph D. Mougous, Pia A. Andrade, FoSheng Hsu, S. Brook Peterson, Paul A. Wiggins, Kelsi Penewit, Stephen J. Salipante, Víctor de Lorenzo, Thomas LaFramboise, Jennifer Kim, James C. Charity, Matthew C. Radey, Elena Velazquez, Marcos H. de Moraes, Simon L. Dove
DNA–protein interactions (DPIs) are central to such fundamental cellular processes as transcription and chromosome maintenance and organization. The spatiotemporal dynamics of these interactions dictate their functional consequences; therefore, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e7081a458391e2a6881c707225d75ea
https://doi.org/10.1101/2021.08.01.454665
https://doi.org/10.1101/2021.08.01.454665
