Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Michael J, DiMartino"'
Autor:
William M. Reiff, Charles DeBrosse, Joyce E Wawro, Elizabeth D Matz, Anvarhusein A. Isab, David T. Hill, C. Frank Shaw, James W. Webb, Michael J. DiMartino, Benjamin M. Jones, R. C. Elder, Don E. Griswold, Angel L Figueroa
Publikováno v:
Inorganic Chemistry. 49:7663-7675
Seleno-auranofin (SeAF), an analogue of auranofin (AF), the orally active antiarthritic gold drug in clinical use, was synthesized and has been characterized by an array of physical techniques and biological assays. The Mossbauer and extended X-ray a
Autor:
G. Stroup, W. A. Galloway, W. High, S. Hoffman, C. Wolff, M. Davis, Michael J. DiMartino, D. Bertolini, S. Davies, J. C. Lee, J. Laydon, M. J. Crimmin
Publikováno v:
Inflammation Research. 46:211-215
Objective and Design: The effects of two hydroxamate inhibitors of metalloproteinase and tumor necrosis factor α (TNFα) processing on endotoxin-induced plasma TNFα and arthritic lesions in adjuvant-induced arthritic (AA) rats were determined.¶Mat
Autor:
Elaine Nicholas Cheeseman, Alison M. Badger, Fontaine C. Bradley, Donald H. Picker, Michael J. DiMartino, David A. Schwartz, James Woodrow Dorman, Christopher K. Mirabelli, Nabil Hanna
Publikováno v:
ChemInform. 22
Spirogermanium (1; 8,8-diethyl-N,N-dimethyl-2-aza-8- germaspiro[4.5]decane-2-propanamine dihydrochloride) is a potent cytotoxic agent in vitro which has demonstrated limited activity in experimental animal tumor models. Subsequently, it has been repo
Autor:
David T, Hill, Anvarhusein A, Isab, Don E, Griswold, Michael J, DiMartino, Elizabeth D, Matz, Angel L, Figueroa, Joyce E, Wawro, Charles, DeBrosse, William M, Reiff, Richard C, Elder, Benjamin, Jones, James W, Webb, C Frank, Shaw
Publikováno v:
Inorganic chemistry. 49(17)
Seleno-auranofin (SeAF), an analogue of auranofin (AF), the orally active antiarthritic gold drug in clinical use, was synthesized and has been characterized by an array of physical techniques and biological assays. The Mössbauer and extended X-ray
Autor:
Nabil Hanna, Robert A. Gabel, G. K. Campbell, Richard A. Macia, Michael J. DiMartino, Anthony C. Silver
Publikováno v:
Toxicology and Applied Pharmacology. 102:117-127
SK&F 101926, a synthetic peptide, is a potent antagonist of vasopressin at both the V2 and the V1 receptors. Following intravenous administration of SK&F 101926 (5 mg/kg), mean arterial pressure (MAP) immediately fell 75 mm Hg. Heart rate increased a
Publikováno v:
Cellular Immunology. 103:54-64
Disease-associated alterations in macrophage functions were assessed by investigating the stages of activation of peritoneal macrophages obtained from adjuvant-induced arthritic rats. The stages of activation were established by defining several func
Autor:
Michael J. DiMartino, Alison M. Badger, Christopher K. Mirabelli, Barbara A. Swift, Thomas C. Schmitt
Publikováno v:
International Journal of Immunopharmacology. 9:621-630
Spirogermanium is a metal-containing compound reported to have antitumor, antiarthritic, antimalarial and immunoregulatory activity. In this study we have demonstrated that spirogermanium inhibited antibody sytnhesis to sheep red blood cells in BDF1
Autor:
Don E. Griswold, George Poste, Michael J. DiMartino, J F Newton, Henry M. Sarau, Paul J. Marshall, John G. Gleason, E. F. Webb, Richard W. Godfrey, Nabil Hanna
Publikováno v:
Biochemical Pharmacology. 36:3463-3470
The effects of SK&F 86002 [5-(4-pyridyl)-6 (4-fluorophenyl)-2,3-dihydroimidazo (2,1-b) thiazole] on the generation of eicosanoids in vitro and on inflammatory responses in vivo are described and compared to other non-steroidal anti-inflammatory drugs
Publikováno v:
Arthritis & Rheumatism. 31:1406-1412
The dual inhibitors of arachidonic acid metabolism, Smith KlineFrench (SKF) 86002, SKF 104351, and phenidone; the corticosteroid, dexamethasone; and the selective cyclooxygenase inhibitors, ibuprofen, indomethacin, naproxen, and piroxicam were evalua
Publikováno v:
Inorganica Chimica Acta. 166:141-146
A series of four tetraalkylammonium gold(III) salts, [R 4 N] + [AuX 4 ] − (R Et, Bu; X Cl,Br) and five tetraalkylammonium gold(I) salts, [R 4 N] + - [AuX 2 ] − [R Et, Bu; X Cl, Br, C 6 H 5 S, S-Glucose- (OAc) 4 ] were prepared, to