Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Michael I. Treshalin"'
Autor:
Michael I. Treshalin, E. V Neborak
Publikováno v:
Russian Journal of Oncology. 23:60-70
Introduction. Topoisomerases influence on DNA topology and are capable of running down their super spiraling molecules by importation of one- or two-chained ruptures with the subsequent restitution and also the negative super rounds or catenae’s. T
Autor:
Michael I. Treshalin, Dominique Schols, Alexander A. Shtil, Dmitry N. Kaluzhny, Yulia L. Volodina, Anastasia A. Kalinina, Yves Pommier, Maria N. Preobrazhenskaya, Vladimir B. Tsvetkov, Lyubov G. Dezhenkova, Helen M. Treshalina, Andrey E. Shchekotikhin, Yuri N. Luzikov, Vladimir I. Romanenko, Michael H.G. Kubbutat, Victor V. Tatarskiy
Publikováno v:
Eur J Med Chem
Anthraquinones and their analogues, in particular heteroarene-fused anthracendiones, are prospective scaffolds for new compounds with improved antitumor characteristics. We herein report the use of a ‘scaffold hopping’ approach for the replacemen
Autor:
Helen M. Treshalina, Dmitry N. Kaluzhny, Andrey E. Shchekotikhin, Aleksey Nikitin, Alexander S. Tikhomirov, Vladimir I. Romanenko, Michael I. Treshalin
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 109
To improve the water solubility of the anticancer drug candidate LCTA-2034 (A1), we investigated the formation of complexes of this anthrax[2,3-b]furan congener with the solubilizing 2-hydroxypropyl derivative of β-cyclodextrin HP-βCD (Cavitron®).