Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Michael Hulse"'
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss , Pp 100415- (2024)
Externí odkaz:
https://doaj.org/article/cd6586de59a5478db37687aef6078703
Autor:
Sarah M. Morgan, Hideki Tanizawa, Lisa Beatrice Caruso, Michael Hulse, Andrew Kossenkov, Jozef Madzo, Kelsey Keith, Yinfei Tan, Sarah Boyle, Paul M. Lieberman, Italo Tempera
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Genome folding in the nucleus plays an important role in regulating gene expression. Here the authors show that 3D genome architecture also plays an important role for gene expression adaptability for the Epstein-Barr Virus (EBV), a virus that is ass
Externí odkaz:
https://doaj.org/article/424a49de5634470e8123f77694842c45
Autor:
Silvia Maifrede, Esteban Martinez, Margaret Nieborowska-Skorska, Daniela Di Marcantonio, Michael Hulse, Bac Viet Le, Huaqing Zhao, Katarzyna Piwocka, Italo Tempera, Stephen M. Sykes, Tomasz Skorski
Publikováno v:
Blood Advances, Vol 1, Iss 19, Pp 1467-1472 (2017)
Externí odkaz:
https://doaj.org/article/fd2fa2b89e564793b75fc27587200a22
Publikováno v:
PLoS Pathogens, Vol 14, Iss 11, p e1007394 (2018)
Latent membrane protein 1 (LMP1) is the major transforming protein of Epstein-Barr virus (EBV) and is critical for EBV-induced B-cell transformation in vitro. Poly(ADP-ribose) polymerase 1 (PARP1) regulates accessibility of chromatin, alters function
Externí odkaz:
https://doaj.org/article/9f28fa3c1e3544ba844a343ca89936aa
Autor:
Tomasz Skorski, Italo Tempera, Mariusz A. Wasik, Katarzyna Piwocka, Huaqing Zhao, Lena N. Lupey-Green, Margaret Nieborowska-Skorska, Daniel Gritsyuk, Michael Hulse, Yashodhara Dasgupta, Reza Nejati, Samantha K. Langer, Katherine Sullivan-Reed, Paulina Podszywalow-Bartnicka, Kayla Martin, Silvia Maifrede
Supplementary Figure S1. BL #1 cells display low HR activity. Supplementary Figure S2. BL #1 induced BL-like leukemia in NSG mice Supplementary Figure S3. IGH/MYC-positive cells are hypersensitive to RAD52 inhibitor. Supplementary Figure S4. IGH/MYC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307bac8ccbcd197c15d10e090a510479
https://doi.org/10.1158/1541-7786.22510833
https://doi.org/10.1158/1541-7786.22510833
Autor:
Tomasz Skorski, Italo Tempera, Mariusz A. Wasik, Katarzyna Piwocka, Huaqing Zhao, Lena N. Lupey-Green, Margaret Nieborowska-Skorska, Daniel Gritsyuk, Michael Hulse, Yashodhara Dasgupta, Reza Nejati, Samantha K. Langer, Katherine Sullivan-Reed, Paulina Podszywalow-Bartnicka, Kayla Martin, Silvia Maifrede
Burkitt lymphoma/leukemia cells carry t(8;14)(q24;q32) chromosomal translocation encoding IGH/MYC, which results in the constitutive expression of the MYC oncogene. Here, it is demonstrated that untreated and cytarabine (AraC)-treated IGH/MYC–posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138250a8532f13cdda3bb04fc0b4cd91
https://doi.org/10.1158/1541-7786.c.6539748
https://doi.org/10.1158/1541-7786.c.6539748
Autor:
Tomasz Skorski, Grant A. Challen, Neil Johnson, Katarzyna Piwocka, Italo Tempera, George S. Vassiliou, Giovanni Martinelli, Jian Huang, Mark D. Minden, Mark R. Litzow, Hugo F. Fernandez, Martin S. Tallman, Elisabeth M. Paietta, Peter Valent, Stephen M. Sykes, Georg Greiner, Giorgia Simonetti, Daniela Di Marcantonio, Ksenia Matlawska-Wasowska, Boris A. Bartholdy, Kumaraswamy N. Chitrala, Antonella Padella, Zhaorui Lian, Zachary Gazze, Lisa Beatrice Caruso, Jozef Madzo, Kelsey Keith, Michael Hulse, Joseph Nacson, Wangisa M.B. Dunuwille, Katherine Sullivan-Reed, Konstantin Golovine, Margaret Nieborowska-Skorska, Bac Viet Le, Silvia Maifrede
Somatic variants in TET2 and DNMT3A are founding mutations in hematological malignancies that affect the epigenetic regulation of DNA methylation. Mutations in both genes often co-occur with activating mutations in genes encoding oncogenic tyrosine k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbb1df0a7c02d673032e64a0cd119330
https://doi.org/10.1158/0008-5472.c.6513157.v1
https://doi.org/10.1158/0008-5472.c.6513157.v1
Autor:
Tomasz Skorski, Grant A. Challen, Neil Johnson, Katarzyna Piwocka, Italo Tempera, George S. Vassiliou, Giovanni Martinelli, Jian Huang, Mark D. Minden, Mark R. Litzow, Hugo F. Fernandez, Martin S. Tallman, Elisabeth M. Paietta, Peter Valent, Stephen M. Sykes, Georg Greiner, Giorgia Simonetti, Daniela Di Marcantonio, Ksenia Matlawska-Wasowska, Boris A. Bartholdy, Kumaraswamy N. Chitrala, Antonella Padella, Zhaorui Lian, Zachary Gazze, Lisa Beatrice Caruso, Jozef Madzo, Kelsey Keith, Michael Hulse, Joseph Nacson, Wangisa M.B. Dunuwille, Katherine Sullivan-Reed, Konstantin Golovine, Margaret Nieborowska-Skorska, Bac Viet Le, Silvia Maifrede
Supplementary Methods and Results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef655f58c103814cc748c3a244a0498
https://doi.org/10.1158/0008-5472.22428823
https://doi.org/10.1158/0008-5472.22428823
Autor:
Chris De Savi, Celina D'Cruz, Anne Marie Mazzola, Ermira Pazolli, Brendon Ladd, Graham Richmond, Claire Sadler, Steve Powell, Rachel Rowlinson, Zena Wilson, Graeme E. Walker, Gareth Davies, Michael Tonge, Stuart E. Pearson, Richard A. Norman, Thomas Moss, Philip MacFaul, Galith Karoutchi, Lyman J.L. Feron, Craig S. Donald, Michael Hulse, Peter Ballard, Camila de Almeida, Jon O. Curwen, Rowena J. Callis, David Buttar, Alfred A. Rabow, Mandy Lawson, Robert H. Bradbury, Hazel M. Weir
Legends for Supplementary Figures 1 - 7.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f2ea8b1988f522a97b4476bc1bfb489
https://doi.org/10.1158/0008-5472.22409537.v1
https://doi.org/10.1158/0008-5472.22409537.v1
Autor:
Chris De Savi, Celina D'Cruz, Anne Marie Mazzola, Ermira Pazolli, Brendon Ladd, Graham Richmond, Claire Sadler, Steve Powell, Rachel Rowlinson, Zena Wilson, Graeme E. Walker, Gareth Davies, Michael Tonge, Stuart E. Pearson, Richard A. Norman, Thomas Moss, Philip MacFaul, Galith Karoutchi, Lyman J.L. Feron, Craig S. Donald, Michael Hulse, Peter Ballard, Camila de Almeida, Jon O. Curwen, Rowena J. Callis, David Buttar, Alfred A. Rabow, Mandy Lawson, Robert H. Bradbury, Hazel M. Weir
Supplementary Figure 1 contains a Western blot showing the amount of estrogen receptor remaining after treatment of MCF-7 cells with AZD9496, fulvestrant and estradiol alongside GAPDH protein levels as an internal gel loading control; Supplementary F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c5919450d0037769dc8885c171e5d8
https://doi.org/10.1158/0008-5472.22409534.v1
https://doi.org/10.1158/0008-5472.22409534.v1