Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Michael Hugh Charlton"'
Autor:
Lindsay Bawden, Deborah Brotherton, Vanessa L. Clark, Richard Testar, Mcdermott Joanne, David Festus Charles Moffat, Yvonne McGovern, Stéphane Pintat, Graham M. A. Wells, Alan Hastings Drummond, Sanjay R. Patel, Alan H. Davidson, Jo Owen, Stephen Davies, Sam Bryant, David Krige, Andrew J. Belfield, Valérie Legris, Lindsey Ann Needham, Elisabeth A. Bone, Francesca Ann Day, Michael Hugh Charlton, A. Donald
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 339:132-142
The therapeutic and toxic effects of drugs are often generated through effects on distinct cell types in the body. Selective delivery of drugs to specific cells or cell lineages would, therefore, have major advantages, in particular, the potential to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99452f8f86d8124b12871827c8e5d797
https://doi.org/10.1124/jpet.111.183640
https://doi.org/10.1124/jpet.111.183640
Autor:
Deborah H. Brotherton, Michael Hugh Charlton, Jo Owen, Richard Testar, Stephen Davies, David Festus Charles Moffat, Vanessa L. Clark
Publikováno v:
MedChemComm. 3:1070
Appending appropriate esters to anti-inflammatory compounds leads to monocyte/macrophage selectivity. This has been demonstrated in p38α MAP kinase in which we observe differential inhibition of phosphorylation of the substrate MAPKAPK2 in stimulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::214ba3aa3925536846faee48d8135c8f
https://doi.org/10.1039/c2md20158e
https://doi.org/10.1039/c2md20158e