Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Michael Hiltensperger"'
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/5634015ad86e414f8ea43b9250478630
Autor:
Celina Tretter, Niklas de Andrade Krätzig, Matteo Pecoraro, Sebastian Lange, Philipp Seifert, Clara von Frankenberg, Johannes Untch, Gabriela Zuleger, Mathias Wilhelm, Daniel P. Zolg, Florian S. Dreyer, Eva Bräunlein, Thomas Engleitner, Sebastian Uhrig, Melanie Boxberg, Katja Steiger, Julia Slotta-Huspenina, Sebastian Ochsenreither, Nikolas von Bubnoff, Sebastian Bauer, Melanie Boerries, Philipp J. Jost, Kristina Schenck, Iska Dresing, Florian Bassermann, Helmut Friess, Daniel Reim, Konrad Grützmann, Katrin Pfütze, Barbara Klink, Evelin Schröck, Bernhard Haller, Bernhard Kuster, Matthias Mann, Wilko Weichert, Stefan Fröhling, Roland Rad, Michael Hiltensperger, Angela M. Krackhardt
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Systemic pan-tumor analyses may reveal the significance of common features implicated in cancer immunogenicity and patient survival. Here, we provide a comprehensive multi-omics data set for 32 patients across 25 tumor types for proteogenomi
Externí odkaz:
https://doaj.org/article/1b677a5e3e974d68b06b73bc60798d1c
Autor:
Celina Tretter, Niklas de Andrade Krätzig, Matteo Pecoraro, Sebastian Lange, Philipp Seifert, Clara von Frankenberg, Johannes Untch, Gabriela Zuleger, Mathias Wilhelm, Daniel P. Zolg, Florian S. Dreyer, Eva Bräunlein, Thomas Engleitner, Sebastian Uhrig, Melanie Boxberg, Katja Steiger, Julia Slotta-Huspenina, Sebastian Ochsenreither, Nikolas von Bubnoff, Sebastian Bauer, Melanie Boerries, Philipp J. Jost, Kristina Schenck, Iska Dresing, Florian Bassermann, Helmut Friess, Daniel Reim, Konrad Grützmann, Katrin Pfütze, Barbara Klink, Evelin Schröck, Bernhard Haller, Bernhard Kuster, Matthias Mann, Wilko Weichert, Stefan Fröhling, Roland Rad, Michael Hiltensperger, Angela M. Krackhardt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/6cae0f5158ae4314ac4ec8b239aa4306
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Adoptive cell therapy (ACT) has seen a steep rise of new therapeutic approaches in its immune-oncology pipeline over the last years. This is in great part due to the recent approvals of chimeric antigen receptor (CAR)-T cell therapies and their remar
Externí odkaz:
https://doaj.org/article/a26d1c6b0efb4953bd9fa3cc5f8b07dc
Autor:
Christina Noll, Michael Hiltensperger, Lilian Aly, Rebecca Wicklein, Ali Maisam Afzali, Christian Mardin, Christiane Gasperi, Achim Berthele, Bernhard Hemmer, Thomas Korn, Benjamin Knier
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundOptical coherence tomography angiography (OCT-A) is a novel technique allowing non-invasive assessment of the retinal vasculature. During relapsing remitting multiple sclerosis (RRMS), retinal vessel loss occurs in eyes suffering from acute
Externí odkaz:
https://doaj.org/article/c7a86caea8a545a1a7e986b441348dd5
Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation
Autor:
Garima Garg, Andreas Muschaweckh, Helena Moreno, Ajithkumar Vasanthakumar, Stefan Floess, Gildas Lepennetier, Rupert Oellinger, Yifan Zhan, Tommy Regen, Michael Hiltensperger, Christian Peter, Lilian Aly, Benjamin Knier, Lakshmi Reddy Palam, Reuben Kapur, Mark H. Kaplan, Ari Waisman, Roland Rad, Gunnar Schotta, Jochen Huehn, Axel Kallies, Thomas Korn
Publikováno v:
Cell Reports, Vol 26, Iss 7, Pp 1854-1868.e5 (2019)
Summary: Foxp3+ regulatory T (Treg) cells restrict immune pathology in inflamed tissues; however, an inflammatory environment presents a threat to Treg cell identity and function. Here, we establish a transcriptional signature of central nervous syst
Externí odkaz:
https://doaj.org/article/1003c933a1db470eb7a891336e58a0bb
Adoptive cell therapy (ACT) has seen a steep rise of new therapeutic approaches in its immune-oncology pipeline over the last years. This is in great part due to the recent approvals of chimeric antigen receptor (CAR)-T cell therapies and their remar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8afb0fa5e81f88ada1ec745deca88f0
https://mediatum.ub.tum.de/doc/1704570/document.pdf
https://mediatum.ub.tum.de/doc/1704570/document.pdf
Autor:
Paulien Baeten, Ibrahim Hamad, Cindy Hoeks, Michael Hiltensperger, Bart Van Wijmeersch, Veronica Popescu, Lilian Aly, Veerle Somers, Thomas Korn, Markus Kleinewietfeld, Niels Hellings, Bieke Broux
In many autoimmune diseases, FOXP3+regulatory T cells (Tregs) skew towards a pro-inflammatory and non-suppressive phenotype and are therefore unable to control the exaggerated autoimmune response. This may largely impact the success of autologous Tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7181f3d74bc7fc174e5735ad8f680daa
https://doi.org/10.1101/2022.10.21.513147
https://doi.org/10.1101/2022.10.21.513147
Autor:
Celina Tretter, Niklas de Andrade Krätzig, Matteo Pecoraro, Sebastian Lange, Philipp Seifert, Clara von Frankenberg, Johannes Untch, Florian S Dreyer, Eva Bräunlein, Mathias Wilhelm, Daniel P Zolg, Thomas Engleitner, Sebastian Uhrig, Melanie Boxberg, Katja Steiger, Julia Slotta-Huspenina, Sebastian Ochsenreither, Nikolas von Bubnoff, Sebastian Bauer, Melanie Boerries, Philipp J Jost, Kristina Schenck, Iska Dresing, Florian Bassermann, Helmut Friess, Daniel Reim, Konrad Grützmann, Katrin Pfütze, Barbara Klink, Evelin Schrock, Bernhard Haller, Bernhard Kuster, Matthias Mann, Wilko Weichert, Stefan Fröhling, Roland Rad, Michael Hiltensperger, Angela M Krackhardt
Systemic pan-tumor analyses may reveal the significance of common features implicated in cancer immunogenicity and patient survival. Here, we provide a comprehensive multi-omics data set for 32 patients across 25 tumor types by combining proteogenomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::072f8796b2b6cbe9530be5f0fd79436c
https://doi.org/10.1101/2022.09.17.508207
https://doi.org/10.1101/2022.09.17.508207
Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal
Autor:
Sainitin Donakonda, Bettina Lorenz-Depiereux, Thomas Misgeld, Andreas Dunkel, Sabine Schmitt, Corinna Dawid, Tina Wang, Kilian Eyerich, Vibor Laketa, Thomas Korn, Kerstin Lohr, David Spiegel, Christian Schmid, Matthew D. Streeter, Percy A. Knolle, Stefanie Eyerich, Luca Simeoni, Norbert Hüser, Annkristin Heine, Caroline Fecher, Jan E. Heil, Michael Hiltensperger, Nina Körber, Daniel Hartmann, Farhah Assaad, Tanja Bauer, Mathias Heikenwalder, Uwe Ahting, Martina Anton, Burkhart Schraven, Hans Zischka, Bastian Höchst, Melanie Laschinger, Thomas Hofmann, Peter J. Murray, Tobias Baumann, Johann Schredelseker
Publikováno v:
Nature Immunology
Nat. Immunol. 21, 555-566 (2020)
Nature immunology 21(5), 555-566 (2020). doi:10.1038/s41590-020-0666-9
Nat. Immunol. 21, 555-566 (2020)
Nature immunology 21(5), 555-566 (2020). doi:10.1038/s41590-020-0666-9
Regulatory myeloid immune cells, such as myeloid-derived suppressor cells (MDSCs), populate inflamed or cancerous tissue and block immune cell effector functions. The lack of mechanistic insight into MDSC suppressive activity and a marker for their i