Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Michael Hewera"'
Publikováno v:
Heliyon, Vol 10, Iss 23, Pp e40562- (2024)
Aneurysmal subarachnoid hemorrhage (aSAH) is a highly fatal and morbid disease. Despite successful coiling or clipping of a ruptured aneurysm, the patients suffer post-aSAH complications, including early brain injury, cerebral vasospasm (CVS), delaye
Externí odkaz:
https://doaj.org/article/d8ffb5c3d1ac4b138e10316991f849b8
Publikováno v:
F1000Research, Vol 10 (2021)
Reports of non-replicable research demand new methods of research data management. Electronic laboratory notebooks (ELNs) are suggested as tools to improve the documentation of research data and make them universally accessible. In a self-guided appr
Externí odkaz:
https://doaj.org/article/f9f5ec6bd2a1478c9e3a670c7e852bf4
Publikováno v:
F1000Research, Vol 10 (2021)
Reports of non-replicable research demand new methods of research data management. Electronic laboratory notebooks (ELNs) are suggested as tools to improve the documentation of research data and make them universally accessible. In a self-guided appr
Externí odkaz:
https://doaj.org/article/b2589c24818a4c92b1930a86009dcbdf
Autor:
Michael Hewera, Ann-Christin Nickel, Nina Knipprath, Sajjad Muhammad, Xiaolong Fan, Hans-Jakob Steiger, Daniel Hänggi, Ulf Dietrich Kahlert
Publikováno v:
F1000Research, Vol 9 (2020)
Background: Increasing concerns emerge regarding the limited success in reproducing data and translating research results into applications. This is a major problem for science, society and economy. Driven by industry or scientific networks, several
Externí odkaz:
https://doaj.org/article/276bfaea3c8c4df7bb9aaccfdb826354
Autor:
Andres Vargas-Toscano, Dilaware Khan, Ann-Christin Nickel, Michael Hewera, Marcel Alexander Kamp, Igor Fischer, Hans-Jakob Steiger, Wei Zhang, Sajjad Muhammad, Daniel Hänggi, Ulf Dietrich Kahlert
Publikováno v:
CNS Oncology, Vol 9, Iss 2 (2020)
Aim: Glioblastoma is a heterogeneous lethal disease, regulated by a stem-cell hierarchy and the neurotransmitter microenvironment. The identification of chemotherapies targeting individual cancer stem cells is a clinical need. Methodology: A robotic
Externí odkaz:
https://doaj.org/article/32b88ec1ba78406b9585cff02a38557d
Autor:
Michael Hewera, Ann-Christin Nickel, Nina Knipprath, Sajjad Muhammad, Xiaolong Fan, Hans-Jakob Steiger, Daniel Hänggi, Ulf Dietrich Kahlert
Publikováno v:
F1000Research, Vol 9 (2020)
Background: Increasing concerns emerge regarding the limited success in reproducing research results. This is a major problem for science, society and economy. Driven by industry or scientific networks, several attempts to combat this crisis are init
Externí odkaz:
https://doaj.org/article/76e7eb13e6eb433b98ca9bd2f25b9346
Autor:
Dymphna Margriet Ouwens, Michael Hewera, Guanzhang Li, Wang Di, Sajjad Muhammad, Daniel Hänggi, Hans-Jakob Steiger, Claudia A. Dumitru, Erol Sandalcioglu, Roland S Croner, Wei Zhang, Or Kakhlon, Ulf D. Kahlert
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 1, p 035 (2022)
Background: The conserved stem cell signaling network canonical Wingless (WNT) plays important roles in development and disease. Aberrant activation of this pathway has been linked to tumor progression and resistance to therapy. Industry and academia
Externí odkaz:
https://doaj.org/article/f8a1d046683142e395b1c011f8831bc2
Autor:
Nadezhda Knauer, Valeria Arkhipova, Guanzhang Li, Michael Hewera, Ekaterina Pashkina, Phuong-Hien Nguyen, Maria Meschaninova, Vladimir Kozlov, Wei Zhang, Roland Croner, Anne-Marie Caminade, Jean-Pierre Majoral, Evgeny Apartsin, Ulf Kahlert
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5691
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (10), pp.5691. ⟨10.3390/ijms23105691⟩
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (10), pp.5691. ⟨10.3390/ijms23105691⟩
International audience; Tumor cells with stem cell properties are considered to play major roles in promoting the development and malignant behavior of aggressive cancers. Therapeutic strategies that efficiently eradicate such tumor stem cells are of
Autor:
Constanze Uhlmann, Ann‐Christin Nickel, Daniel Picard, Andrea Rossi, Guanzhang Li, Barbara Hildebrandt, Gabriele Brockerhoff, Farina Bendt, Ulrike Hübenthal, Michael Hewera, Hans‐Jakob Steiger, Dagmar Wieczorek, Aristoteles Perrakis, Wei Zhang, Marc Remke, Katharina Koch, Julia Tigges, Roland S. Croner, Ellen Fritsche, Ulf D. Kahlert
Publikováno v:
Biotechnology Journal. 17:2100693
Limitations in genetic stability and recapitulating accurate physiological disease properties challenge the utility of patient-derived (PD) cancer models for reproducible and translational research. A portfolio of isogenic human induced pluripotent s
Autor:
Ulf D. Kahlert, Or Kakhlon, Wei Zhang, Roland S Croner, Erol Sandalcioglu, Claudia A. Dumitru, Hans-Jakob Steiger, Daniel Hänggi, Sajjad Muhammad, Wang Di, Guanzhang Li, Michael Hewera, Dymphna Margriet Ouwens
Publikováno v:
Frontiers in Bioscience-Landmark. 27:1
The conserved stem cell signaling network canonical Wingless (WNT) plays important roles in development and disease. Aberrant activation of this pathway has been linked to tumor progression and resistance to therapy. Industry and academia have substa