Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Michael Henrich"'
Autor:
Götz Schmidt, Isabelle Greif, Sabrina Müller, Melanie Markmann, Fabian Edinger, Michael Sander, Christian Koch, Michael Henrich
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundThe unique ability of the respiratory tract to protect the integrity of the airways by removing potentially harmful substances is defined as mucociliary clearance. This complex physiological mechanism protects the lower airways by ridding t
Externí odkaz:
https://doaj.org/article/b67ffe1de48a4706a3dfefa15a42ce87
Autor:
Götz Schmidt, Gerrit Rienas, Sabrina Müller, Katrin Richter, Michael Sander, Christian Koch, Michael Henrich
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Mucociliary clearance is a pivotal physiological mechanism that protects the lung by cleaning the airways from pollution and colonization, thereby preventing infection. Ciliary function is influenced by various signal transduction cascades,
Externí odkaz:
https://doaj.org/article/2d89770185d846a1907836fa244a7e4e
Autor:
Götz Schmidt, Gerrit Rienas, Sabrina Müller, Fabian Edinger, Michael Sander, Christian Koch, Michael Henrich
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Mucociliary clearance is a pivotal physiological mechanism that protects the lung by ridding the lower airways of pollution and colonization by pathogens, thereby preventing infections. The fixed 20:1 combination of cafedrine and theodren
Externí odkaz:
https://doaj.org/article/c714c8d7ea784515bf8495c5cf207108
Publikováno v:
The Scientific World Journal, Vol 10, Pp 917-923 (2010)
Externí odkaz:
https://doaj.org/article/52d7d7ab4d6a4fe6a7349c717c9988d5
Autor:
Sebastian Weiterer, Thomas Kohlen, Florian Veit, Lydia Sachs, Florian Uhle, Christoph Lichtenstern, Markus A Weigand, Michael Henrich
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143163 (2015)
BackgroundCiliary beating by respiratory epithelial cells continuously purges pathogens from the lower airways. Here we investigated the effect of the fungal cell wall polysaccharides Galactomannan (GM) and Zymosan (Zym) on the adrenergic activated p
Externí odkaz:
https://doaj.org/article/8c9299c517a6417f92a7f30cca350a28
Autor:
Sebastian Weiterer, Dagmar Schulte, Sabrina Müller, Thomas Kohlen, Florian Uhle, Markus A Weigand, Michael Henrich
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91705 (2014)
The tracheal epithelium prevents via its highly effective clearance mechanism the contamination of the lower airways by pathogens. This mechanism is driven by ciliary bearing cells which are not only in contact with the gas phase; in addition they ar
Externí odkaz:
https://doaj.org/article/773460d3af954ce2ba74aa9bac2bc32e
Autor:
Christian Koch, Michael Sander, Michael Henrich, Sebastian Weiterer, Maximilian Carl Droll, Markus A. Weigand, Sabrina Müller
Publikováno v:
Antimicrobial Agents and Chemotherapy
The mucociliary clearance of lower airways is modulated by different physiologic stimuli and also by pathophysiologic agents like polluting substances or pharmaceutical molecules. In the present investigation, we measured the particle transport veloc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb923165bfeff5db4c0c6c1d5a6b04a1
https://doi.org/10.1128/aac.00669-21
https://doi.org/10.1128/aac.00669-21
Autor:
Michael Henrich, Melanie Markmann, Emmanuel Schneck, Michael Sander, Markus A. Weigand, Christoph Lichtenstern, Christoph Arens, Christian Koch
Publikováno v:
International Journal of Clinical Pharmacy. 42:72-79
Background Echinocandins are well-established agents for the treatment of patients with fungal infections, but growing evidence questions their safety in special patient populations prone to systemic inflammatory responses. Objective The study aimed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f693759f8dd0c03a32859886c8d7e1dd
https://doi.org/10.1007/s11096-019-00939-8
https://doi.org/10.1007/s11096-019-00939-8
Autor:
Markus A. Weigand, Christian Koch, Sabrina Müller, Sebastian Weiterer, Michael Henrich, Michael Sander
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
The antimycotic drug caspofungin is known to alter the cell function of cardiomyocytes and the cilia-bearing cells of the tracheal epithelium. The objective of this study was to investigate the homeostasis of intracellular Ca2+ concentration ([Ca2+]i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d153ac7839f4277b4836145eb23900
http://europepmc.org/articles/PMC7367263
http://europepmc.org/articles/PMC7367263
Publikováno v:
Annals of Medicine and Surgery
Amiodarone-induced pulmonary toxicity (APT) is a severe side effect that can lead to lung fibrosis or fatal respiratory failure. Usually APT occurs during long term therapy after administration of prolonged loading doses or high cumulative doses. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc01433e800092a3cac6cbd7a0bb4c8
http://europepmc.org/articles/PMC5537372
http://europepmc.org/articles/PMC5537372