Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Michael Heisig"'
Publikováno v:
Mathematics and Mechanics of Solids. 25:1046-1059
In-silico methods are valuable tools for understanding the barrier function of the skin. The key benefit is that mathematical modelling allows the interplay between cell shape and function to be elucidated. This study focuses on the viable (living) e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::092a1b6c5f7339e722bfe78ce67d2dad
https://doi.org/10.1177/1081286517743297
https://doi.org/10.1177/1081286517743297
Autor:
Detlef Ehlert, Michael Heisig
Publikováno v:
Computers and Electronics in Agriculture. 93:10-16
In past years, research was conducted to investigate the potential of laser rangefinders and scanners for vehicle-based measuring of crop stand physical parameters. High coefficients of determination (R^2>0.90) were found between the crop biomass and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0ea237bc758ead46ff1424008ce5ddf
https://doi.org/10.1016/j.compag.2013.01.002
https://doi.org/10.1016/j.compag.2013.01.002
Autor:
Johanna M. Brandner, Michael Heisig, Katja Bäsler, Arne Naegel, Sophia Bergmann, Michaela Zorn-Kruppa
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 242
The skin protects our body from external assaults like pathogens, xenobiotics or UV irradiation. In addition, it prevents the loss of water and solutes. To fulfill these important tasks, a complex barrier system has developed which comprises the stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2c4df927cdb63cbee0d4be8f3f447e
https://pubmed.ncbi.nlm.nih.gov/27521894
https://pubmed.ncbi.nlm.nih.gov/27521894
Autor:
Michael Heisig, Ulrich F. Schaefer, Arne Naegel, Gabriel Wittum, Claus-Michael Lehr, Tsambika Hahn
Publikováno v:
Computing and Visualization in Science. 14:327-339
In this paper we present a mathematical diffusion model describing the transient transdermal penetration of two non-volatile substances, the lipophilic flufenamic acid and the hydrophilic caffeine, after finite dosing in an aqueous vehicle system. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8422b3a82bb6fdc2cf9735c44dbb25e9
https://doi.org/10.1007/s00791-012-0186-8
https://doi.org/10.1007/s00791-012-0186-8
Publikováno v:
Precision Agriculture. 11:650-663
In recent years, laser rangefinder sensors have been introduced to the practice and research of agricultural engineering. In research, laser rangefinders have been investigated in horticulture and agriculture. For vehicle-based determination of crop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f4a49fba10c976d4d81ec6663330b7f
https://doi.org/10.1007/s11119-010-9191-4
https://doi.org/10.1007/s11119-010-9191-4
Publikováno v:
Precision Agriculture. 9:321-337
Yield maps derived from yield mapping systems are often erroneous not only due to limitations in measuring the yield precisely but due to insufficient consideration of the requirements of yield mapping systems in practice as well. Aerial images of cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30c2c76be9110ad90ec25185faef3cbd
https://doi.org/10.1007/s11119-008-9076-y
https://doi.org/10.1007/s11119-008-9076-y
Autor:
Andreas Henning, Gabriel Wittum, Ulrich F. Schaefer, Claus-Michael Lehr, Karl-Heinz Kostka, Dirk Neumann, Jarmila Zbytovská, Arne Naegel, Steffi Hansen, Michael Heisig
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 68:352-367
Mathematical modeling of skin transport is considered a valuable alternative of in-vitro and in-vivo investigations especially considering ethical and economical questions. Mechanistic diffusion models describe skin transport by solving Fick's 2nd la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41893f20a4cebca174177b2bc309e49b
https://doi.org/10.1016/j.ejpb.2007.05.012
https://doi.org/10.1016/j.ejpb.2007.05.012
Publikováno v:
Computing and Visualization in Science. 9:117-130
We present a three-dimensional geometry model with tetrakaidecahedra for the biphasic model stratum corneum (SC) membrane ΩSC consisting of corneocytes embedded in a lipid matrix. Two practical domains for ΩSC are realized: the simple model SC-memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d95286090824015b17a1de44d3f9ce2e
https://doi.org/10.1007/s00791-006-0017-x
https://doi.org/10.1007/s00791-006-0017-x
Publikováno v:
Computational Biophysics of the Skin ISBN: 9789814463843
Computational Biophysics of the Skin
Computational Biophysics of the Skin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d571f54d7e1d4d1e956b960c498f079c
https://doi.org/10.1201/b17205-12
https://doi.org/10.1201/b17205-12
Publikováno v:
Pharmaceutical Research. 13:421-426
Purpose. The diffusion equation should be solved for the non-steady-state problem of drug diffusion within a two-dimensional, biphasic stratum corneum membrane having homogeneous lipid and corneocyte phases. Methods. A numerical method was developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bacf86c7029ceb48a0a35edb8808aadc
https://doi.org/10.1023/a:1016048710880
https://doi.org/10.1023/a:1016048710880